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🧪Data Scientist

Staff / Sr. Staff Data Scientist, Statistical Genetics

Valo Health · Remote
// classified as
Data Scientist (Modeling, experiments, research.)
posted
51d ago
location
Remote
languages
python, r
tools
> stack
pythonr
> education
msphd
> description
<div class="content-intro"><h3 class="x_MsoNormal">About Us</h3> <p class="x_MsoNormal">Valo Health is a human-centric, AI-enabled biotechnology company working to make new drugs for patients faster. The company’s Opal Computational Platform transforms drug discovery and development through a unique combination of&nbsp;real-world data, AI, human translational models and predictive chemistry.&nbsp;</p> <p class="x_MsoNormal">Our talented team of biologists, chemists and engineers, armed with advanced AI/ML tools, work together to break down traditional R&amp;D silos and accelerate the speed and scale of drug discovery and development.&nbsp;</p> <p class="x_MsoNormal">Valo is committed to hiring diverse talent, prioritizing growth and development, fostering an inclusive environment, and creating opportunities to bring together a group of different experiences, backgrounds, and voices to work together. We embrace new ways of learning, solve complex problems and welcome diverse perspectives that can help us advance patient-centric innovation.&nbsp;</p> <p class="x_MsoNormal">Valo is headquartered in Lexington, MA, with additional offices in New York, NY and Tel Aviv, Israel. &nbsp;To learn more, visit <u><a href="http://www.valohealth.com/" data-outlook-id="5b38894b-e5d7-4841-bcf8-af9440ad7230" data-auth="NotApplicable" data-linkindex="0">www.valohealth.com</a></u>. &nbsp;</p></div><p><strong>About the Role</strong></p> <p><span data-contrast="none">As a <strong>Staff / Sr.&nbsp;Staff Da</strong></span><strong><span data-contrast="none">ta Scientist&nbsp;</span></strong><span data-contrast="none">on the Statistical Genetics team in the Translation Data Science Group, you will lead teams in applying Valo’s Opal computational platform to&nbsp;identify&nbsp;and&nbsp;validate&nbsp;drug targets. You will work in a multidisciplinary environment alongside data scientists, biologists, software engineers, and clinical development experts in building a powerful computational platform for advancing the discovery and development of new medicines. Using unique and diverse human-centric datasets, we will solve challenging problems at the interface of scientific discovery,&nbsp;methodology, technology, and software. We are looking for data scientists who can match scientific breadth with technical excellence.</span><span data-ccp-props="{&quot;335559685&quot;:-20,&quot;335559737&quot;:-20}">&nbsp;</span></p> <p><span data-contrast="none">In this role, you will&nbsp;be responsible for&nbsp;leading the application of&nbsp;cutting-edge&nbsp;genetics approaches to discover and develop drug targets using genetic, multi-omic, and clinical data. Successful candidates will lead in matrixed settings, composed of diverse sets of scientists, entrepreneurs, and domain experts in ways that cut across traditional industry boundaries.</span><span data-ccp-props="{&quot;335559685&quot;:-20,&quot;335559737&quot;:-20}">&nbsp;</span></p> <p><strong><span data-contrast="none">What&nbsp;You’ll&nbsp;Do…</span></strong><span data-ccp-props="{}">&nbsp;</span></p> <ul> <li>Apply robust, generalizable computational solutions to core scientific problems in statistical genetics, working closely with senior team members.</li> <li>Work with a diverse set of stakeholders to support project plans that address program needs, and contribute to prioritization of analytical tasks under guidance.</li> <li>Work with an array of data types using R or Python in cloud environments.</li> <li>Be comfortable with scientific uncertainty and embrace curiosity and creative solutions. Many of the challenges we're trying to address don't have known solutions or clear processes to arrive at answers.</li> <li>Collaborate with drug discovery and clinical development teams to help ensure the relevance and impact of the insights you generate.</li> <li>Be a dynamic and active team member, championing shared coding standards, participating in code review, and providing regular updates of your work and input into the work of your colleagues.</li> </ul> <p><strong><span data-contrast="none">What You Bring…</span></strong><span data-ccp-props="{&quot;335559739&quot;:0}">&nbsp;</span></p> <ul> <li>BS + 5-8, MS + 3-5 or PhD + <strong>1-3 years of experience</strong> in statistical genetics, computational sciences (e.g., computational biology, molecular biology), or a related field</li> <li>Experience in performing and working with results of genetically anchored studies:</li> <li>Experience conducting genome-wide association studies (GWAS) and follow-up analyses including computing and using (omic)QTL for Mendelian randomization and colocalization</li> <li>Experience with the computation and application of rare genetic variation analyses (LoF analysis, burden testing, identity-by-descent detection, functional variant annotation)</li> <li>Experience working with UKBiobank data or similar datasets, integrating genomics, multi-omics, and clinical information</li> <li>Experience with statistical genetics, exploratory data analysis, and data visualization</li> <li>Experience researching cardiometabolic disease</li> <li>Proficient in Python or R programming and at least basic knowledge of the other</li> <li>Proficient in a command line interface</li> <li>Familiarity with version control (e.g., git) and collaborative code writing practices such as code review</li> <li>Experience developing analysis pipelines</li> </ul> <p><strong>You May Also Bring...</strong></p> <ul> <li data-leveltext="" data-font="Symbol" data-listid="1" data-list-defn-props="{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}" data-aria-posinset="16" data-aria-level="1"><span data-contrast="none">Experience in machine learning, probabilistic graphical modeling, and/or causal inference</span></li> <li data-leveltext="" data-font="Symbol" data-listid="1" data-list-defn-props="{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}" data-aria-posinset="16" data-aria-level="1">Experience with working with electronic health record data, personally identifiable information (PII), protected health information (PHI) data, or HIPAA compliance </li> <li data-leveltext="" data-font="Symbol" data-listid="1" data-list-defn-props="{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}" data-aria-posinset="16" data-aria-level="1">Experience in drug discovery and development<span data-ccp-props="{&quot;335559739&quot;:0}">&nbsp;</span></li> </ul> <p>&nbsp; &nbsp;</p><div class="content-pay-transparency"><div class="pay-input"><div class="title">Remote Salary Range</div><div class="pay-range"><span>$170,000</span><span class="divider">&mdash;</span><span>$215,000 USD</span></div></div><div class="pay-input"><div class="title">CA Salary Range</div><div class="pay-range"><span>$200,600</span><span class="divider">&mdash;</span><span>$253,500 USD</span></div></div></div><div class="content-conclusion"><p></p> <h3><span data-contrast="none"><span class="LineBox SCXP134197409 BCX0"><span class="TextRun SCXP134197409 BCX0" lang="EN-US" data-usefontface="false" data-contrast="none"><span class="NormalTextRun SCXP134197409 BCX0"></span></span></span></span></h3> <h3><span data-contrast="none"><span class="LineBox SCXP134197409 BCX0"><span class="TextRun SCXP134197409 BCX0" lang="EN-US" data-usefontface="false" data-contrast="none"><span class="NormalTextRun SCXP134197409 BCX0"></span></span></span></span></h3> <p><span data-contrast="none"><strong><span class="LineBox SCXP134197409 BCX0"><span class="TextRun SCXP134197409 BCX0" lang="EN-US" data-usefontface="false" data-contrast="none"><span class="NormalTextRun SCXP134197409 BCX0">Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Valo Health</span></span></span><span class="LineBox SCXP134197409 BCX0"><span class="TextRun SCXP134197409 BCX0" lang="EN-US" data-usefontface="false" data-contrast="none"><span class="NormalTextRun SCXP134197409 BCX0"> currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Valo Health's</span></span></span><span class="LineBox SCXP134197409 BCX0"><span class="TextRun SCXP134197409 BCX0" lang="EN-US" data-usefontface="false" data-contrast="none"><span class="NormalTextRun SCXP134197409 BCX0"> good faith estimate as of the date of publication and may be modified in the future.</span></span></span></strong></span></p> <p><strong><span data-contrast="none"><span class="LineBox SCXP134197409 BCX0"><span class="TextRun SCXP134197409 BCX0" lang="EN-US" data-usefontface="false" data-contrast="none"><span class="NormalTextRun SCXP134197409 BCX0"></span></span></span></span></strong></p> <p><strong><em><span data-contrast="none">Please note: At this time, we are only able to consider candidates who&nbsp;</span></em><span data-contrast="none"><strong data-stringify-type="bold">currently</strong></span><span data-contrast="none"><strong data-stringify-type="bold">&nbsp;</strong></span><em><span data-contrast="none">have permanent US work authorization without the need for immediate or future sponsorship.</span></em></strong></p> <p><span data-contrast="none"><span class="LineBox SCXP134197409 BCX0"><span class="TextRun SCXP134197409 BCX0" lang="EN-US" data-usefontface="false" data-contrast="none"><span class="NormalTextRun SCXP134197409 BCX0"></span></span></span></span></p> <p></p></div>