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&lt;p&gt;&lt;strong&gt;Company Summary: &lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;What if…&lt;/strong&gt;you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?&lt;/p&gt;
&lt;p&gt;Montai Health is a privately held, early-stage biotechnology company developing a platform for understanding and leveraging complex molecular interactions within organisms to solve global challenges in human health and sustainability. The company leverages a multidisciplinary approach that integrates tools ranging from machine learning and big data to multi-omics and high-throughput screening.&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&amp;nbsp;&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;em&gt;Montai&lt;/em&gt;&amp;nbsp;Health is seeking a creative, motivated&amp;nbsp;&lt;strong&gt;Scientist, Analytics Development&lt;/strong&gt;&amp;nbsp;to play a role in the Delivery team’s efforts to identify and characterize natural products, and formulations. S/he will be an expert in various analytical processes needed for oral delivery systems of small molecules, natural products, and related samples. The candidate will contribute critically to shaping the vision and strategy of the Delivery team. S/he will bring a strong entrepreneurial orientation, demonstrate strong communication skills, and be comfortable working in and contributing to a very dynamic and cross-functional team environment. As a member of this early team of scientists, you can expect to engage deeply in interdisciplinary research. Employees will enjoy a dynamic, rapidly expanding organization that will have a broad impact on human health. We offer a competitive starting salary and benefits.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Develop and implement novel biochemical and biophysical analysis methodology to characterize natural products, novel delivery formulations, and&amp;nbsp;&lt;em&gt;in vivo&lt;/em&gt;&amp;nbsp;pharmacokinetics of small molecules&lt;/li&gt;
&lt;li&gt;Develop and contribute to pre-formulation and formulation analysis of natural products and small molecules&lt;/li&gt;
&lt;li&gt;Oversee in-house instruments, including maintenance, troubleshooting, and method development/optimization&lt;/li&gt;
&lt;li&gt;Identify and collaborate with CROs to fulfill analytical needs of the projects&lt;/li&gt;
&lt;li&gt;Collaborate closely with other computational and wet lab scientists – wear multiple hats as needed in a fast-paced environment&lt;/li&gt;
&lt;li&gt;Report results to scientific team and management.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Ph.D. focusing on Analytical Chemistry, Natural Product Chemistry, Biochemistry, Biological Engineering and/or related field or equivalent experience.&lt;/li&gt;
&lt;li&gt;2-5+ years of industry experience with natural products and/or small molecule analysis with diverse analytical chemistry techniques, including HPLC, LC-MS/MS, etc.&lt;/li&gt;
&lt;li&gt;Experience with analytical development on lipid-based formulations and oral delivery systems is a plus&lt;/li&gt;
&lt;li&gt;Ability to learn cross-team scientific functions and wear multiple hats in a small company setting&lt;/li&gt;
&lt;li&gt;Excellent communication and presentation skills, capable of conveying technical information in a clear and thorough manner&lt;/li&gt;
&lt;li&gt;Self-driven and demonstrated ability in working with highly skilled teams in a fast-paced, entrepreneurial setting&lt;/li&gt;
&lt;/ul&gt;
&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;&amp;nbsp;&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;Flagship Pioneering and our ecosystem companies are &lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;&amp;nbsp;&lt;/div&gt;
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&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

Senior Scientist/Scientist, Analytics Development

&lt;p&gt;&lt;strong&gt;Company Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Laronde is pioneering a platform that offers a completely novel way of modulating human biology via Endless RNA™ (eRNA). eRNA is a uniquely engineered RNA that can be programmed to express diverse proteins inside the body. Laronde is rapidly scaling to support the development of multiple programs across many disease areas.&amp;nbsp;&lt;/p&gt;
&lt;p&gt;Laronde was founded in 2017 by Flagship Labs, the innovation foundry of Flagship Pioneering. Laronde has a highly collaborative, dedicated culture, driven to achieve our vision of “making eRNA an essential class of medicines to everyone, everywhere”. To learn more, please visit the company’s website at https://www.laronde.bio.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Laronde is seeking an outstanding Drug Delivery Scientist to join Laronde’s Targeted Delivery team that is pushing the boundaries and potential of a new class of RNA therapeutics. The position will play an integral role in a multidisciplinary team that seeks to push the possibilities of endless RNA therapeutics.&amp;nbsp;&lt;br&gt;&lt;br&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Bioconjugation of targeting motifs for development of novel eRNA&lt;/li&gt;
&lt;li&gt;Purification of synthetic biologics and downstream analytical methods&lt;/li&gt;
&lt;li&gt;Protein conjugation and other biochemical linkage techniques&lt;/li&gt;
&lt;li&gt;Running of gels of different formats for the analysis of nucleic acids and proteins&lt;/li&gt;
&lt;li&gt;Critical data analysis skills, attention to details and troubleshooting abilities.&lt;/li&gt;
&lt;li&gt;Maintain detailed records of experimental protocols and data in electronic laboratory notebook in accordance with company policy.&lt;/li&gt;
&lt;li&gt;Effectively collaborate with a fully integrated research team to facilitate the success of projects.&lt;/li&gt;
&lt;li&gt;Excellent organizational skills and documentation practices.&lt;/li&gt;
&lt;li&gt;Additional duties and responsibilities as required.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;PhD in Chemistry, Biochemistry, Cell Biology or a related field, or MS with 8+ years, or BS with 12+ years’ experience in industry or academia is required&lt;/li&gt;
&lt;li&gt;Experience with conjugation /strategies of ligands for drug delivery&lt;/li&gt;
&lt;li&gt;Chemistry experience such as organic synthesis, HPLC, purification methods, NMR and/or LCMS&lt;/li&gt;
&lt;li&gt;Experience with linker chemistry or antibody-drug conjugates (ADCs)&lt;/li&gt;
&lt;li&gt;Demonstrated ability in working with highly skilled teams in a fast-paced, entrepreneurial, and technical environment&lt;/li&gt;
&lt;li&gt;Excellent communication, scientific writing, and presentation skills&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Additional helpful experience:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Experience with tissue culture, transfections, biochemical assays, or protein characterization&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;em&gt;Laronde is &lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;&lt;/em&gt;&lt;em&gt;: Laronde does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Laronde or its employees is strictly prohibited unless contacted directly by Laronde’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Laronde, and Laronde will not owe any referral or other fees with respect thereto&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;

Scientist I , Targeted Delivery Bioconjugation

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&lt;p&gt;&lt;strong&gt;Company Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;FL87, Inc. is a privately held, early-stage biotechnology company developing a novel approach to gene therapy that can address currently untreatable diseases.&lt;/p&gt;
&lt;p&gt;FL87 was founded by Flagship Pioneering, an innovation enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Seres Therapeutics (NASDAQ:MCRB), Moderna (MRNA), Syros Pharmaceuticals (SYRS), Rubius Therapeutics (RUBY), Axcella Health, Evelo Biosciences (EVLO), and Indigo Agriculture.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;The Sr. Research Associate will be primarily responsible for testing new gene therapy technology in mammalian cells. This individual will join a dynamic, rapidly growing, and highly collaborative team that combines significant biologic drug discovery experience with pioneering discoveries driving a novel biological platform.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Performs research and/or development in collaboration with others&lt;/li&gt;
&lt;li&gt;Makes detailed observations, analyzes data and interprets results&lt;/li&gt;
&lt;li&gt;Exercises technical discretion in the design, execution and interpretation of experiments that contribute to project goals&lt;/li&gt;
&lt;li&gt;Prepares technical reports, summaries, protocols, and quantitative analyses.&lt;/li&gt;
&lt;li&gt;Investigates, creates and develops new methods and technologies for project advancement&lt;/li&gt;
&lt;li&gt;Maintains high level of professional expertise through familiarity with scientific literature and novel technologies&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Preferred Qualifications (one or more): &lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Mammalian biology: cell culture, transfection and/or transduction, flow cytometry analysis, rtPCR, next generation sequencing, fluorescent and bioluminescent microscopy, western blotting, ELISA.&lt;/li&gt;
&lt;li&gt;Gene editing experience: using Cas9 or other approach therapeutically and quantitatively assaying editing efficiency and accuracy with state of the art technology.&lt;/li&gt;
&lt;li&gt;Gene therapy experience: AAV, liposome-mediated delivery of DNA or mRNA.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Basic Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;M.S. or B.S. in Biological Engineering, Genetics, Molecular Biology, Immunology or related field.&lt;/li&gt;
&lt;li&gt;2+ years of industry experience is preferred.&lt;/li&gt;
&lt;li&gt;A strong self-starter, independent thinker, with a strong attention to detail.&lt;/li&gt;
&lt;li&gt;Demonstrated industry experience or academic achievement, as evidenced by publications in high impact journals or drug development is required&lt;/li&gt;
&lt;li&gt;Proven hands-on experience with cell-based and molecular biology assays with a variety of readout technologies, such as, but not limited to: flow cytometry, microscopy, mRNA expression analysis, western blotting.&lt;/li&gt;
&lt;li&gt;Excellent communication and presentation skills, capable of conveying technical information in a clear and thorough manner.&lt;/li&gt;
&lt;li&gt;Eager to work with highly-skilled and dynamic teams in a fast-paced, entrepreneurial and technical setting.&lt;/li&gt;
&lt;li&gt;Confident, execution focused, team oriented, with an ability to thrive in an entrepreneurial environment.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;More About Flagship Pioneering&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;We are creative optimists and we would love for you to consider joining our team!&amp;nbsp; See &lt;a href=&quot;https://www.flagshippioneering.com/join/roles&quot;&gt;all our open opportunities&lt;/a&gt; across Flagship Pioneering’s Ecosystem!&lt;/p&gt;
&lt;p&gt;&lt;a href=&quot;https://www.flagshippioneering.com/&quot;&gt;Flagship Pioneering&lt;/a&gt; conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, the firm has applied a unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $34 billion in aggregate value. To date, Flagship is backed by more than $4.4 billion of aggregate capital commitments, of which over $1.9 billion has been deployed toward the founding and growth of its pioneering companies alongside more than $10 billion of follow-on investments from other institutions. The current Flagship ecosystem comprises 41 transformative companies, including:&amp;nbsp; Axcella Health (NASDAQ: AXLA), Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO),&amp;nbsp; Foghorn Therapeutics, Indigo Ag, Kaleido Biosciences (NASDAQ: KLDO), Moderna (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology, Seres Therapeutics (NASDAQ: MCRB), and Syros Pharmaceuticals (NASDAQ: SYRS).&lt;/p&gt;
&lt;p&gt;We believe pioneering is best done by teams, and that it is a process that can be taught, learned, and replicated.&amp;nbsp; Learn more about our &lt;a href=&quot;https://www.flagshippioneering.com/process&quot;&gt;Company Creation Model&lt;/a&gt;.&lt;/p&gt;
&lt;p&gt;Can Breakthrough Innovations Be Made Systematically&lt;a href=&quot;https://www.flagshippioneering.com/stories/can-innovations-be-made-systematically-a-conversation-with-noubar-afeyan&quot;&gt;? A Conversation With Noubar Afeyan&lt;/a&gt;, Flagship Pioneering’s CEO.&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt;Flagship Pioneering and our ecosystem companies are committed to &lt;strong&gt;equal employment opportunity&lt;/strong&gt;&amp;nbsp;regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies:&lt;/strong&gt;&amp;nbsp; Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates.&amp;nbsp; The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team.&amp;nbsp;&amp;nbsp; Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/p&gt;
&lt;/div&gt;

Senior Research Associate, Cell Biology 

&lt;div class=&quot;content-intro&quot;&gt;&lt;p&gt;Vizgen, Inc. – Cambridge, MA&lt;/p&gt;
&lt;p&gt;&lt;br&gt;Vizgen is a rapidly growing company developing the next generation of spatially resolved genomic profiling tools that enable researchers to gain new insight into the biological systems that underlie human health and disease. The company&#x27;s groundbreaking MERFISH spatial transcriptomics technology images RNA molecules with high accuracy and unrivaled detection efficiency at subcellular resolution. MERFISH provides transformative insight into a wide range of tissue-scale basic research and translational medicine in oncology, immunology, neuroscience, infectious disease, developmental biology, and regenerative medicine. For more information, go to www.vizgen.com&lt;/p&gt;&lt;/div&gt;&lt;p&gt;&lt;strong&gt;Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;We are seeking a Senior Bioinformatics Applications Scientist with a proven track record of establishing standardized bioinformatics analysis procedures to address diverse biological applications using genomics data. The Bioinformatics Applications Scientist will be responsible for leading the evaluation of available tools and standardizing analysis frameworks for users of Vizgen’s MERSCOPE platform. As a Bioinformatics Applications Scientist at Vizgen, you will drive successful engagement with Vizgen’s spatial transcriptomic data among the research community through establishing a comprehensive analysis framework that enables researchers to identify the best analysis for their biological question. The ideal candidate will have experience analyzing data from single-cell gene expression, immunofluorescence, FISH, and/or spatial gene expression experiments. This is an exciting opportunity for an experienced and driven individual to become an expert on the next generation of genomics technologies while working in a fast-paced, dynamic company.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;What will you be doing:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Lead development of an analysis framework for reaching biologically relevant conclusions from data generated by Vizgen’s MERSCOPE platform.&lt;/li&gt;
&lt;li&gt;Document and track analysis trends from emerging spatial transcriptomics demonstrations and publications.&lt;/li&gt;
&lt;li&gt;Plan and execute validation testing plans for Vizgen’s new bioinformatics tools to ensure biological results from the tools are robust and valid.&lt;/li&gt;
&lt;li&gt;Help the product development group compile customer bioinformatics requirements for new Vizgen-developed analysis tools.&lt;/li&gt;
&lt;li&gt;Serve as an externally-facing expert on Vizgen software, data, and bioinformatics products.&lt;/li&gt;
&lt;li&gt;Facilitate integration with bioinformatics tools developed by external partners or academic groups.&lt;/li&gt;
&lt;li&gt;Provide timely and expert resolutions to escalated issues and questions.&lt;/li&gt;
&lt;li&gt;Consolidate and represent customer and partner feedback to communicate to the internal R&amp;amp;D teams to refine user experience and ensure Vizgen customers are able to easily perform the analysis that is needed for their research.&lt;/li&gt;
&lt;li&gt;Build accessible software training material and tutorials for internal and external customers running MERSCOPE measurements and partners interested in integrating MERSCOPE output into their 3&lt;sup&gt;rd&lt;/sup&gt; party tools.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Lead internal bioinformatics training for the sales, field support, and lab services groups.&lt;/li&gt;
&lt;li&gt;Travel to meet with customers and field teams at trade shows, seminars, and technical meetings.&amp;nbsp;&amp;nbsp;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;To be successful in this role, you must have:&lt;/strong&gt;&amp;nbsp;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;5+ years of Bioinformatics experience&lt;/li&gt;
&lt;li&gt;PhD in Biology, Bioinformatics, Computer Science, or similar discipline or equivalent work experience&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Strong background in statistics&lt;/li&gt;
&lt;li&gt;Demonstrated experience implementing, troubleshooting and supporting bioinformatics software and pipelines.&lt;/li&gt;
&lt;li&gt;Demonstrated experience establishing and maintaining successful collaborations and partnerships&lt;/li&gt;
&lt;li&gt;Strong scripting and programming experience.&lt;/li&gt;
&lt;li&gt;Experience with Amazon AWS, GCP, Linux, and high performance computing.&lt;/li&gt;
&lt;li&gt;Demonstrated ability to help wetlab scientist understand their data.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Nice to have skills &amp;amp; experience:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Experience analyzing spatial transcriptomic data&lt;/li&gt;
&lt;li&gt;Experience leading a bioinformatics group&lt;/li&gt;
&lt;li&gt;Expertise in neuroscience or oncology&lt;/li&gt;
&lt;li&gt;Experience contributing to open source software projects&lt;/li&gt;
&lt;li&gt;Experience with image processing and spatial analysis&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;#LI-DNI&lt;/p&gt;&lt;div class=&quot;content-conclusion&quot;&gt;&lt;p&gt;If you aren&#x27;t sure you meet every requirement but are excited about what you read here, please consider applying! We believe diversity drives innovation.&amp;nbsp; Above all, we&#x27;re looking for the right person with skills and talent to grow the company together all while enriching your professional and scientific experience.&lt;/p&gt;
&lt;p&gt;We offer a competitive salary, meaningful stock ownership, 401K, health benefits, a great work environment and the opportunity to enter a high-growth startup company. We are recruiting candidates who have demonstrated leadership and excellence throughout their careers and are excited by the prospect of tackling challenging technical problems.&lt;/p&gt;
&lt;p&gt;&lt;em&gt;This position may be subject to pre-employment checks, including driving history check, drug screening and a background check for any convictions directly related to its duties and responsibilities. All pre-employment checks will comply with all applicable federal, state, and local laws.&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;WE ARE AN EQUAL OPPORTUNITY/AFFIRMATIVE ACTION EMPLOYER&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Vizgen affords equal employment opportunity to all qualified persons regardless of race, color, religious creed, national origin, age, military status, sexual orientation, disability, genetic information, gender identity, gender expression or gender unless based upon a bona fide occupational qualification.&lt;/p&gt;&lt;/div&gt;

Senior Bioinformatics Applications Scientist 

&lt;p&gt;&lt;strong&gt;Company Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Laronde is pioneering a platform that offers a completely novel way of modulating human biology. Endless RNA™ (eRNA), is a uniquely engineered RNA that can be programmed to express diverse proteins inside the body. It is long lasting, non-immunogenic, allows for repeat dosing, and offers flexibility in formulation and delivery.&lt;/p&gt;
&lt;p&gt;Laronde was founded in 2017 by Flagship Labs, the innovation foundry of Flagship Pioneering. Laronde has raised a record breaking $440 Million in a Series B Financing to advance the development of its eRNA platform. There is a broad pipeline across therapeutic categories with the goal of 100 medicines in 10 years. To learn more, please visit the company’s website at https://www.laronde.bio/about.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;The Position:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;We are seeking an experienced and driven data engineer who shares our vision of data as a strategic asset in enabling cutting-edge research. In this role you will design and develop cloud-based solutions to advance our goals by ensuring that the data that drives our science is Findable, Accessible, Interoperable, and Reusable. The ideal candidate will have a background working with life science organizations, experience with a variety of scientific data types, and expertise in cloud computing. It’s also essential to be a strong data modeler and coder, with an exceptional ability to deliver near-term value while helping companies plan for the future.&lt;/p&gt;
&lt;p&gt;The successful candidate will act as the glue between wet and dry labs within the company, ensuring that digital solutions meet the needs of bench scientists, computational/data/ML scientists and senior management while aligning with long term strategic objectives. As an early member of a privately held, well-funded, early-stage platform biotechnology company, you will have an opportunity to contribute to building our digital strategy and have significant influence on technology platform development, with many options to apply your skills and talent as the company continues to expand.&lt;/p&gt;
&lt;p&gt;This role is based at our Somerville, MA site. Role can be hybrid onsite 2-3 days per week.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Specific Responsibilities&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Create and maintain process maps of all the ways data accumulates and flows into and throughout the company&lt;/li&gt;
&lt;li&gt;Create automated pipelines for various workloads, including raw instrument data processing, computational workflows, and information reporting&lt;/li&gt;
&lt;li&gt;Organize and manage all structured and unstructured scientific data used by the company&lt;/li&gt;
&lt;li&gt;Design data models for entities, assays, and results from scientific experiments and analyses&lt;/li&gt;
&lt;li&gt;Drive consensus and implement standards around scientific research metadata&lt;/li&gt;
&lt;li&gt;Implement scalable, cloud-based solutions to support dramatic increases in data and analysis demands&lt;/li&gt;
&lt;li&gt;Integrate data and metadata from a variety of internal and external sources&lt;/li&gt;
&lt;li&gt;Deliver data products and visualizations to stakeholders&lt;/li&gt;
&lt;li&gt;Establish engineering standards around languages, DevOps and Agile project management&lt;/li&gt;
&lt;li&gt;Assist in the management and administration of our AWS environment&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Minimum Qualifications &lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;MS degree (or BS with equivalent experience) in Bioinformatics, Informatics, Computer Science, Data Science or other related discipline&lt;/li&gt;
&lt;li&gt;3+ years’ experience in data engineering/research informatics in the life sciences&lt;/li&gt;
&lt;li&gt;Demonstrated proficiency with cloud development (AWS strongly preferred) using infrastructure-as-code frameworks&lt;/li&gt;
&lt;li&gt;Proficiency in with modeling and using data stored in relational and NoSQL databases&lt;/li&gt;
&lt;li&gt;Experience integrating multi-omic datasets&lt;/li&gt;
&lt;li&gt;Experience building processes supporting data transformation, data structures, metadata, dependency, and workload management&lt;/li&gt;
&lt;li&gt;Strong DevOps, project management and organization skills&lt;/li&gt;
&lt;li&gt;A people person with an exceptional ability to collaborate with scientists of different backgrounds&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Preferred Qualifications&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Experience with workflow orchestration software (Nextflow, SnakeMake, etc) and deploying it in cloud environments such as AWS Batch&lt;/li&gt;
&lt;li&gt;Experience with ELN/LIMS (Benchling preferred)&lt;/li&gt;
&lt;li&gt;Experience supporting and working with cross-functional teams in a fast-paced environment&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;em&gt;Laronde is &lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;&lt;/em&gt;&lt;em&gt;: Laronde does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Laronde or its employees is strictly prohibited unless contacted directly by Laronde’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Laronde, and Laronde will not owe any referral or other fees with respect thereto&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;

Data Engineer / Senior Data Engineer

&lt;p&gt;&lt;strong&gt;What if…&lt;/strong&gt; you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies to transform human health and sustainability?&lt;/p&gt;
&lt;p&gt;Flagship Pioneering&#x27;s venture creation engine has conceived and created companies such as Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology (NASDAQ: SANA), Generate Biomedicines, and Tessera Therapeutics. Since its launch in 2000, Flagship has applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $212 billion in aggregate value. To date, Flagship has deployed over $2.5 billion in capital toward the founding and growth of its pioneering companies alongside more than $19 billion of follow-on investments from other institutions. In 2021, Flagship Pioneering was ranked 12thglobally on Fortune’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;The Company:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;FL86, Inc. is a privately held, early-stage company developing a novel genomics platform and therapeutics for diseases with a large unmet need.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Drive and generate proof of concept data in cell-based and pharmacology models aimed at establishing the translational science of FL86 mosaics genetics&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Develop and apply novel disease specific cell-based and in vivo pharmacological models to generate robust data package leading towards go/no go decisions&lt;/li&gt;
&lt;li&gt;Execute cell-based assays to assess intracellular signaling pathways, the biological activity of small molecules and biologics in disease relevant tissue specific cells&lt;/li&gt;
&lt;li&gt;Conduct proof of concept translational studies in primary tissues (fresh and fixed) to confirm target rationale, target engagement and biological response&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;B.S./M.S. in cell biology, molecular biology, pharmacology or similar technical fields&lt;/li&gt;
&lt;li&gt;3-5 years of experience in a biotech or pharmaceutical company (the title will be adjusted for the level of experience)&lt;/li&gt;
&lt;li&gt;Extensive hands-on experience in mammalian cell culture including primary cells&lt;/li&gt;
&lt;li&gt;Experience in translational models, e.g., precision cut slices is a plus&lt;/li&gt;
&lt;li&gt;Execution focused, team oriented, and highly motivated&lt;/li&gt;
&lt;li&gt;Experience with the following techniques is highly preferred: Northern and Western blotting, RT-qPCR, RNA-seq, cloning, cell culture, immunohistochemistry&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Preferred Attributes:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Critical data analysis, attention to detail, and troubleshooting abilities&lt;/li&gt;
&lt;li&gt;Cell biologist with pharmacology background&lt;/li&gt;
&lt;/ul&gt;
&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;&amp;nbsp;&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;&lt;strong&gt;Location:&lt;/strong&gt; Cambridge, MA&amp;nbsp;&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;&amp;nbsp;&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;Flagship Pioneering and our ecosystem companies are&amp;nbsp;&lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt;&amp;nbsp;regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;&amp;nbsp;&lt;/div&gt;
&lt;/div&gt;
&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/div&gt;
&lt;/div&gt;

Sr. Research Associate/Associate Scientist, Cell Biology 

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&lt;p&gt;&lt;strong&gt;Company Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Ring Therapeutics Inc. is a privately held, early-stage biotechnology company pioneering a completely novel form of gene therapy by exploiting a family of naturally occurring commensal viruses to create the first redosable and targetable DNA medicines. This approach enables a powerful new class of tropic, persistent, non-integrating vectors that overcome the immunogenicity, and limited tropism of existing gene therapy vectors. Ring Therapeutics is leveraging this versatile technology to develop a broad pipeline of novel, targeted medicines for disease with high unmet medical need.&lt;br&gt;&lt;br&gt;Ring Therapeutics was founded by Flagship Pioneering, focused on launching breakthrough companies based on internally conceived innovations and insights. Flagship Pioneering has created over 40 groundbreaking companies over the past fifteen years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Seres Therapeutics (NASDAQ: MCRB), Moderna (MRNA), Syros Pharmaceuticals (SYRS), Rubius Therapeutics (RUBY), Axcella Health (AXLA), Evelo Biosciences (EVLO), and Indigo Agriculture.&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;The&amp;nbsp;Scientist/Sr. Scientist in Analytical Development of Technical Operations team supports multiple preclinical and early development phase platforms with advanced separation and biophysics technologies. The successful candidate will be a subject matter expert and key contributor to a highly technical, diverse, and collaborative team of scientists and engineers. The position offers the opportunity to interface with Process Development, Quality Control, Manufacturing, Regulatory, and external research institutes, and contract development manufacturing organizations. We are searching for an innovative, independent, and motivated scientist with high level of scientific curiosity and critical thinking to join our team and contribute to various aspects of the platform research and development.&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Develop and qualify analytical/biophysical assays related to purity, empty/full ratio, and physical/chemical properties to support viral vector testing and characterization. Techniques include SEC-MALS, CE-SDS, cIEF, AUC, and mass photometry.&lt;/li&gt;
&lt;li&gt;Planning, designing, and conducting the experiments and data analysis to support development and qualification of analytical/biophysical methods, generation, and interpretation of high-quality data.&lt;/li&gt;
&lt;li&gt;Author, review and/or approve technical documents (protocols, reports, test methods, etc) or regulatory filings ensuring high technical standards and compliance with applicable regulatory guidelines to support analytical/biophysical methods.&lt;/li&gt;
&lt;/ul&gt;
&lt;ul&gt;
&lt;li&gt;Collaborate with process development team members to ensure timely delivery of high-quality data of routine analytical testing.&lt;/li&gt;
&lt;/ul&gt;
&lt;ul&gt;
&lt;li&gt;Be a technical resource for junior staff and use expertise in laboratory technology as a functional resource/trainer.&lt;/li&gt;
&lt;/ul&gt;
&lt;ul&gt;
&lt;li&gt;Understand project timelines and deliverables and plan/prioritize project work with departmental, functional, and external stakeholders to support multiple programs.&lt;/li&gt;
&lt;li&gt;Represent biophysics team to provide project update and advice to cross-functional teams and contribute scientific insights into multiple platforms.&lt;/li&gt;
&lt;/ul&gt;
&lt;ul&gt;
&lt;li&gt;Participate analytical working group meetings to evaluate analytical strategy and implement new technologies related to analytical/biophysical methods.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;PhD degree in analytical chemistry, biophysics, or related field 0+ years relevant industry experience for Scientist position, and 3+ years of relevant industry experience for Sr. Scientist position.&lt;/li&gt;
&lt;li&gt;Master’s degree in analytical chemistry, biophysics, or related field with 3+ years relevant industry experience for Scientist position, and minimum 6+ of relevant industry experience for Sr. Scientist position.&lt;/li&gt;
&lt;li&gt;Experience working with biotherapeutics, viral vector, and payload is preferred. Experience managing research associate is preferred for Sr. Scientist position.&lt;/li&gt;
&lt;li&gt;Demonstrated expertise developing separation and biophysical methods (eg. CE, cIEF, HPLC, sub-vis particle, AUC, and Octet protein binding assays) is essentially preferred&lt;/li&gt;
&lt;li&gt;Demonstrated hands-on experiences with Sciex PA800 Plus, Protein Simple Maurice, Wyatt MALS, and Agilent 1260 HPLC.&lt;/li&gt;
&lt;/ul&gt;
&lt;ul&gt;
&lt;li&gt;Experience in analytical assay development, qualification, and tech transfer to comply with current regulatory standards is preferred.&lt;/li&gt;
&lt;li&gt;Author and review technical documents such as protocols, reports, internal presentations, method development and qualification reports.&lt;/li&gt;
&lt;li&gt;Proven record of technical expertise and ability to gain in-depth understanding of new technologies and scientific concepts. Independently design and implement scientifically sound and creative solutions.&lt;/li&gt;
&lt;li&gt;Understanding of project timelines and deliverables and plan and coordinate project work with departmental and cross functional peers (process development and QC).&lt;/li&gt;
&lt;/ul&gt;
&lt;ul&gt;
&lt;li&gt;Excellent communication skills and ability to work effectively both independently and in a collaborative cross-functional environment with internal and external partners is essential&lt;/li&gt;
&lt;/ul&gt;
&lt;ul&gt;
&lt;li&gt;Ability to work in a fast-paced, startup environment with demonstrated capacity to multi-task and independently prepare, execute, and document lab experiments.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;Flagship Pioneering and our ecosystem companies are&amp;nbsp;&lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt;&amp;nbsp;regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;&lt;em&gt;Recruitment &amp;amp; Staffing Agencies&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;/div&gt;

Scientist/Sr. Scientist, Analytical development, Biophysics

&lt;p&gt;&lt;strong&gt;What if…&lt;/strong&gt; you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies to transform human health and sustainability?&lt;/p&gt;
&lt;p&gt;Flagship Pioneering&#x27;s venture creation engine has conceived and created companies such as Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology (NASDAQ: SANA), Generate Biomedicines, and Tessera Therapeutics. Since its launch in 2000, Flagship has applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $212 billion in aggregate value. To date, Flagship has deployed over $2.5 billion in capital toward the founding and growth of its pioneering companies alongside more than $19 billion of follow-on investments from other institutions. In 2021, Flagship Pioneering was ranked 12thglobally on Fortune’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;The Company:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;FL86, Inc. is a privately held, early-stage company developing a novel genomics platform and therapeutics for diseases with a large unmet need.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Responsible for the translational validation of discovery platform targets in cell-based and in disease-relevant pharmacological models&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;The successful candidate will work both independently and as part of a team to design, plan and execute high-quality biochemical, cell-based and translational assays&lt;/li&gt;
&lt;li&gt;Lead the development and execution of cell-based assays to assess biological signaling pathways, the biological activity of small molecules, biologics or nucleotide-based compounds&lt;/li&gt;
&lt;li&gt;Define tissue and disease-specific target engagement levels, establish, and run biomarker plans and translational PK/PD assessment&lt;/li&gt;
&lt;li&gt;Critical data analysis, attention to detail, and troubleshooting abilities&lt;/li&gt;
&lt;li&gt;Mentor and train research associates as needed&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Ph.D. in Cell Biology, Molecular Biology, Biochemistry, Bioengineering or related discipline with &amp;gt; 5 years of experience in a biotech or pharmaceutical company (the title will be adjusted for the level of experience)&lt;/li&gt;
&lt;li&gt;Deep knowledge and understanding of cell biology. Proficient in experimental design, assay execution, troubleshooting, data analysis, and data interpretation&lt;/li&gt;
&lt;li&gt;Extensive hands-on experience in mammalian cell culture including primary cells and in handling tissues&lt;/li&gt;
&lt;li&gt;The ideal candidate has previous experience in RNA biochemistry and structural biology, cell-based genetic manipulations (e.g., siRNA, ASO) and RNA/DNA delivery&lt;/li&gt;
&lt;li&gt;Experience in the following techniques is a plus: FACS, RT-qPCR, RNA-seq, cloning, cell culture, IHC and quantitative image analysis, Meso Scale Discovery, HALO image analysis software.&lt;/li&gt;
&lt;li&gt;Strong written and oral presentation skills&lt;/li&gt;
&lt;li&gt;Execution focused, team oriented, and highly motivated&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Preferred Attributes:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Experience with translational cell-based and pharmacology models&amp;nbsp;&lt;/li&gt;
&lt;/ul&gt;
&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;&amp;nbsp;&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;&lt;strong&gt;Location:&lt;/strong&gt; Cambridge, MA&amp;nbsp;&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;&amp;nbsp;&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;Flagship Pioneering and our ecosystem companies are&amp;nbsp;&lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt;&amp;nbsp;regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;&amp;nbsp;&lt;/div&gt;
&lt;/div&gt;
&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/div&gt;
&lt;/div&gt;

Principal/Senior Scientist, Cell Biology 

&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;dhkj5-0-0&quot;&gt;
&lt;p&gt;&lt;strong&gt;Position: &lt;/strong&gt;Associate Scientist/Scientist I, RNA Biochemistry (leveling flexible based on experience)&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Location: &lt;/strong&gt;Cambridge, MA&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;What if…&lt;/strong&gt;you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?&lt;/p&gt;
&lt;p&gt;Radial Therapeutics Inc. is a privately held, well-funded, early-stage biotechnology company leveraging novel insights in RNA biology. Radial Therapeutics’s proprietary platform identifies novel disease targets and develops new therapeutic modalities targeting RNA, providing new strategies to treat or cure a range of diseases including rare genetic diseases, neurological diseases, and cancers.&lt;/p&gt;
&lt;p&gt;Radial Therapeutics, Inc. was founded in Flagship’s venture creation engine, where companies such as Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), and Editas Medicines (NASDAQ: EDIT) were conceived and created.&amp;nbsp; Since Flagship’s founding in 2000, the firm has originated and fostered the development of more than 100 scientific ventures, resulting in over $180 billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents.&amp;nbsp;&amp;nbsp;&lt;/p&gt;
&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;We are seeking an RNA biochemist/screening scientist to join our passionate team. The individual will be responsible for synthesizing RNA reagents for biochemical and biophysical assays across a number of technologies to discover and dissect interactions between RNA-small molecules, and RNA-proteins. This role offers the unique opportunity to collaborate with colleagues across Drug Discovery, RNA Platform, and Target Biology. In addition, this role offers enormous growth potential to impact the build of Radial’s proprietary discovery platform. Successful candidates will be creative self-starters who thrive in a fast-paced, action-oriented team environment and display a clear passion for science and impact. The individual will have demonstrated agility and nimbleness to progress scientific discoveries with an overt attitude of positivity when facing challenges.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Responsibilities: &lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Design and produce high quality RNA reagents for &lt;em&gt;in vitro&lt;/em&gt; studies to drive Radial’s discovery platform&lt;/li&gt;
&lt;li&gt;Execute plate-based screening assays to interrogate RNA-small molecule, RNA-protein, and protein-small molecule interactions&lt;/li&gt;
&lt;li&gt;Analyze, interpret, document, and present data to the scientific and leadership teams&lt;/li&gt;
&lt;li&gt;Work closely with an entrepreneurial, highly-collaborative, and interdisciplinary team&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;B.S./M.S. in Biochemistry, Biology or related field plus 5 years of industry experience or equivalent education (Ph.D)&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Hands-on experience with &lt;em&gt;in vitro&lt;/em&gt; protein or RNA production, purification, and quality assessment assays required&lt;/li&gt;
&lt;li&gt;Experience with &lt;em&gt;in vitro&lt;/em&gt; RNA techniques including &lt;em&gt;in vitro&lt;/em&gt; transcription (IVT), RNA purification, and RNA labeling highly desirable&lt;/li&gt;
&lt;li&gt;Hands-on experience with plate-based assay platforms such as FP, HTRF, Alpha a plus&lt;/li&gt;
&lt;li&gt;Experience with laboratory automation and semi-automated workflows a plus&lt;/li&gt;
&lt;li&gt;Detailed oriented, team-focused mentality and drive to overcome challenges in creative ways&lt;/li&gt;
&lt;/ul&gt;
&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;Flagship Pioneering and our ecosystem companies are &lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;&amp;nbsp;&lt;/div&gt;
&lt;/div&gt;
&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

Associate Scientist/Scientist I, RNA Biochemistry

&lt;p&gt;&lt;strong&gt;Company Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Laronde is pioneering a platform that offers a completely novel way of modulating human biology. Endless RNA™ (eRNA), is a uniquely engineered RNA that can be programmed to express diverse proteins inside the body. It is long lasting, non-immunogenic, allows for repeat dosing, and offers flexibility in formulation and delivery.&lt;/p&gt;
&lt;p&gt;Laronde was founded in 2017 by Flagship Labs, the innovation foundry of Flagship Pioneering. Laronde has raised a record breaking $440 Million in a Series B Financing to advance the development of its eRNA platform. There is a broad pipeline across therapeutic categories with the goal of 100 medicines in 10 years. To learn more, please visit the company’s website at https://www.laronde.bio/about.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Laronde is seeking an outstanding Scientist/Senior Research Associate, RNA Molecular Biology to join a multidisciplinary team of experimental and computational synthetic biologists and engineers responsible for study, design and optimization of novel endless RNA (eRNA) therapeutics. The ideal candidate will lead experimental efforts to characterize eRNA structure in vitro and inside living cells in a high-throughput manner through applying the world-class chemical probing tools coupled with next-generation sequencing (NGS) technologies. If you are a passionate and purposeful scientist keen on testing your hypotheses and learning from some of the best synthetic biologists and engineers whilst getting to work with complex multidimensional data sets, then we are looking for you.&lt;/p&gt;
&lt;p&gt;&lt;br&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Perform NGS library preparation from eRNA samples using plate-based molecular biology techniques including PCR, reverse transcription, and nucleic acid ligation.&lt;/li&gt;
&lt;li&gt;Develop and apply novel NGS library preparation methods to enable assays of eRNA structure in a variety of contexts and help the team to understand the eRNA sequence-structure-function relationships.&lt;/li&gt;
&lt;li&gt;Work with automated liquid handlers for high throughput NGS library preparation.&lt;/li&gt;
&lt;li&gt;Carefully document experiments in an electronic lab notebook and communicate results to collaborators.&lt;/li&gt;
&lt;li&gt;Work closely with an interdisciplinary team of experimental and computational biologists to design experiments, analyze data, interpret, and present your results at department meetings.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;B.S. or M.S. in Molecular Biology, Biochemistry or Biology with 5+ (B.S.) or 3+ years (M.S.) of relevant industry experience.&lt;/li&gt;
&lt;li&gt;Demonstrated ability to establish NGS methods and perform sequencing-based assays.&lt;/li&gt;
&lt;li&gt;Extensive experience with Illumina NGS library preparation, including RNA-Seq library preparation.&lt;/li&gt;
&lt;li&gt;Strong molecular biology skills, including cell culture, total RNA extraction, qRT-PCR, and gel electrophoresis.&lt;/li&gt;
&lt;li&gt;Experience with Pacbio SMRTbell library preparation and sequencing is desired.&lt;/li&gt;
&lt;li&gt;Experience with NGS data analysis is a strong plus.&lt;/li&gt;
&lt;li&gt;Demonstrated ability in working with highly collaborative teams in a fast-paced, entrepreneurial and technical environment.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;em&gt;Laronde is &lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;&lt;/em&gt;&lt;em&gt;: Laronde does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Laronde or its employees is strictly prohibited unless contacted directly by Laronde’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Laronde, and Laronde will not owe any referral or other fees with respect thereto&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;

Scientist / Senior Research Associate RNA Molecular Biology and NGS

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&lt;p&gt;&lt;strong&gt;Bioinformatics Scientist / Senior Scientist&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Harbinger Health, a Flagship-founded company, is pioneering early cancer detection. Harbinger aims to detect cancer, at the earliest stages, to save lives. Our platform leverages proprietary biological insights and artificial intelligence to enable high-resolution, molecular views on cancer from blood. We are a highly dynamic, entrepreneurial, and innovation-driven organization seeking collaborative, passionate, and dedicated people to join our team.&lt;/p&gt;
&lt;p&gt;Flagship Pioneering conceives, creates, resources, and develops first-in-category bioplatform companies to transform human health and sustainability. Since its launch in 2000, the firm has, through its Flagship Labs unit, applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in more than $200 billion in aggregate value. To date, Flagship has deployed over $2.5 billion in capital toward the founding and growth of its pioneering companies alongside more than $19 billion of follow-on investments from other institutions. The current Flagship ecosystem comprises 42 transformative companies, including Axcella Health (Nasdaq: AXLA), Codiak BioSciences (Nasdaq: CDAK) Denali Therapeutics (Nasdaq: DNLI), Evelo Biosciences (Nasdaq: EVLO), Foghorn Therapeutics (Nasdaq: FHTX), Indigo Ag, Kaleido Biosciences (Nasdaq: KLDO), Moderna (Nasdaq: MRNA), Omega Therapeutics (Nasdaq: OMGA), Rubius Therapeutics (Nasdaq: RUBY), Sana Biotechnology (Nasdaq: SANA), Seres Therapeutics (Nasdaq: MCRB), and Sigilon Therapeutics (Nasdaq: SGTX).&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Harbinger Health is seeking an innovative and highly motivated Scientist/Senior Scientist in the bioinformatics department.&amp;nbsp; The candidate will be responsible for R&amp;amp;D of bioinformatics algorithms and drawing insights from explorations of the genomics data.&lt;/p&gt;
&lt;p&gt;The successful candidate should have significant experience in data science in genomics, demonstrated via first author publications and conference presentations.&amp;nbsp; Also demonstrating ability to write high quality code is needed, as the algorithms will transition from R&amp;amp;D into production pipeline in a regulated environment.&amp;nbsp; Additionally, the candidate will need to demonstrate strong communication skills, especially with teams who closely collaborate with bioinformatics.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Develop and perform bioinformatics analyses of NGS data, with emphasis on bisulfite sequencing&lt;/li&gt;
&lt;li&gt;Analyze internal and external data sets to address biological questions critical to Harbinger’s core mission.&lt;/li&gt;
&lt;li&gt;Apply rigorous statistical methods for extracting and summarizing biological insight that live in high dimensionality space&lt;/li&gt;
&lt;li&gt;Work closely with other computational and experimental scientists to design experiments&lt;/li&gt;
&lt;li&gt;Effectively communicate findings to stakeholders&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Required Skills:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Ph.D. in bioinformatics, computational biology, biostatistics, or a related quantitative field; or M.S. with relevant work experience&lt;/li&gt;
&lt;li&gt;3+ years experience in analysis of complex biological datasets, demonstrable via publications, presentations, and/or patents&lt;/li&gt;
&lt;li&gt;Strong scientific programming experience in Python (preferred) or R or Matlab, demonstrated via github or publications&lt;/li&gt;
&lt;li&gt;Experienced and proficient with experimental design, data processing, statistical analysis, and bioinformatics analysis/reporting of next-generation sequencing (DNA, bisulfite, RNAseq, single-cell NGS, and/or exome sequencing) and microarray platforms.&lt;/li&gt;
&lt;li&gt;Comfortable in working with a Linux environment, using high performance computing in a cloud&lt;/li&gt;
&lt;li&gt;Motivated and team oriented, with track record to thrive in a fast-paced and multi-tasking environment.&lt;/li&gt;
&lt;li&gt;Strong communication and presentation skills.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;Flagship Pioneering and our ecosystem companies are&amp;nbsp;&lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt;&amp;nbsp;regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/p&gt;
&lt;p&gt;&lt;em&gt;Recruitment &amp;amp; Staffing Agencies:&amp;nbsp; Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates.&amp;nbsp; The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team.&amp;nbsp;&amp;nbsp; Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

Bioinformatics Scientist/Senior Scientist

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&lt;p&gt;&lt;strong&gt;Company Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;FL87, Inc. is a privately held, early-stage biotechnology company developing a novel approach to gene therapy that can address currently untreatable diseases.&lt;/p&gt;
&lt;p&gt;FL87 was founded by Flagship Pioneering, an innovation enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Seres Therapeutics (NASDAQ:MCRB), Moderna (MRNA), Syros Pharmaceuticals (SYRS), Rubius Therapeutics (RUBY), Axcella Health, Evelo Biosciences (EVLO), and Indigo Agriculture.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;The Research Associate or Sr. Research Associate will be primarily responsible for testing new gene therapy technology in mammalian cells. This individual will join a dynamic, rapidly growing, and highly collaborative team that combines significant biologic drug discovery experience with pioneering discoveries driving a novel biological platform.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Performs research and/or development in collaboration with others&lt;/li&gt;
&lt;li&gt;Makes detailed observations, analyzes data and interprets results&lt;/li&gt;
&lt;li&gt;Exercises technical discretion in the design, execution and interpretation of experiments that contribute to project goals&lt;/li&gt;
&lt;li&gt;Prepares technical reports, summaries, protocols, and quantitative analyses.&lt;/li&gt;
&lt;li&gt;Investigates, creates and develops new methods and technologies for project advancement&lt;/li&gt;
&lt;li&gt;Maintains high level of professional expertise through familiarity with scientific literature and novel technologies&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Preferred Qualifications (one or more): &lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Mammalian biology: cell culture, transfection and/or transduction, flow cytometry analysis, rtPCR, next generation sequencing, fluorescent and bioluminescent microscopy, western blotting, ELISA.&lt;/li&gt;
&lt;li&gt;Gene editing experience: using Cas9 or other approach therapeutically and quantitatively assaying editing efficiency and accuracy with state of the art technology.&lt;/li&gt;
&lt;li&gt;Gene therapy experience: AAV, liposome-mediated delivery of DNA or mRNA.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Basic Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;M.S. or B.S. in Biological Engineering, Genetics, Molecular Biology, Immunology or related field.&lt;/li&gt;
&lt;li&gt;2+ years of industry experience is preferred.&lt;/li&gt;
&lt;li&gt;A strong self-starter, independent thinker, with a strong attention to detail.&lt;/li&gt;
&lt;li&gt;Demonstrated industry experience or academic achievement, as evidenced by publications in high impact journals or drug development is required&lt;/li&gt;
&lt;li&gt;Proven hands-on experience with cell-based and molecular biology assays with a variety of readout technologies, such as, but not limited to: flow cytometry, microscopy, mRNA expression analysis, western blotting.&lt;/li&gt;
&lt;li&gt;Excellent communication and presentation skills, capable of conveying technical information in a clear and thorough manner.&lt;/li&gt;
&lt;li&gt;Eager to work with highly-skilled and dynamic teams in a fast-paced, entrepreneurial and technical setting.&lt;/li&gt;
&lt;li&gt;Confident, execution focused, team oriented, with an ability to thrive in an entrepreneurial environment.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;More About Flagship Pioneering&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;We are creative optimists and we would love for you to consider joining our team!&amp;nbsp; See &lt;a href=&quot;https://www.flagshippioneering.com/join/roles&quot;&gt;all our open opportunities&lt;/a&gt; across Flagship Pioneering’s Ecosystem!&lt;/p&gt;
&lt;p&gt;&lt;a href=&quot;https://www.flagshippioneering.com/&quot;&gt;Flagship Pioneering&lt;/a&gt; conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, the firm has applied a unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $34 billion in aggregate value. To date, Flagship is backed by more than $4.4 billion of aggregate capital commitments, of which over $1.9 billion has been deployed toward the founding and growth of its pioneering companies alongside more than $10 billion of follow-on investments from other institutions. The current Flagship ecosystem comprises 41 transformative companies, including:&amp;nbsp; Axcella Health (NASDAQ: AXLA), Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO),&amp;nbsp; Foghorn Therapeutics, Indigo Ag, Kaleido Biosciences (NASDAQ: KLDO), Moderna (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology, Seres Therapeutics (NASDAQ: MCRB), and Syros Pharmaceuticals (NASDAQ: SYRS).&lt;/p&gt;
&lt;p&gt;We believe pioneering is best done by teams, and that it is a process that can be taught, learned, and replicated.&amp;nbsp; Learn more about our &lt;a href=&quot;https://www.flagshippioneering.com/process&quot;&gt;Company Creation Model&lt;/a&gt;.&lt;/p&gt;
&lt;p&gt;Can Breakthrough Innovations Be Made Systematically&lt;a href=&quot;https://www.flagshippioneering.com/stories/can-innovations-be-made-systematically-a-conversation-with-noubar-afeyan&quot;&gt;? A Conversation With Noubar Afeyan&lt;/a&gt;, Flagship Pioneering’s CEO.&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt;Flagship Pioneering and our ecosystem companies are committed to &lt;strong&gt;equal employment opportunity&lt;/strong&gt;&amp;nbsp;regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies:&lt;/strong&gt;&amp;nbsp; Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates.&amp;nbsp; The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team.&amp;nbsp;&amp;nbsp; Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/p&gt;
&lt;/div&gt;

Research Associate, Cell Biology 

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&lt;p&gt;&lt;strong&gt;What if… &lt;/strong&gt;you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?&lt;/p&gt;
&lt;p&gt;Montai Health is a privately held, early-stage biotechnology company developing a platform for understanding and leveraging complex molecular interactions within organisms to solve global challenges in human health and sustainability. The company leverages a multidisciplinary approach that integrates tools ranging from machine learning and big data to multi-omics and high-throughput screening.&lt;/p&gt;
&lt;p&gt;At Montai, we nurture a bold, spirited and leading-edge culture dedicated to strengthening human health:&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;We are one team with omnidirectional trust, empowered and accountable.&lt;/li&gt;
&lt;li&gt;We are strong as individuals but stronger as a team and we are committed to excellence.&lt;/li&gt;
&lt;li&gt;We have a sense of urgency and persistence and we are crazily confident that we can make a difference.&lt;/li&gt;
&lt;li&gt;We need to be comfortable with the uncomfortable and be rigorous and we recognize that failure is data.&lt;/li&gt;
&lt;li&gt;We care for diversity in people, thought, personality, opinions, background and distinctiveness.&lt;/li&gt;
&lt;li&gt;We have a sense of humor to help us manage through our strategic noise.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Montai Health is seeking an experienced Translational Biologist or In Vivo Immunologist to join our Translational Biology Team to establish a biological testing and analysis pipeline for small &amp;amp; large&amp;nbsp;&lt;em&gt;in vivo&lt;/em&gt;&amp;nbsp;models, as well as a broad set of disease models, run and oversee proof of concept studies, and, ultimately, build preclinical data packages to enable clinical studies.&lt;/p&gt;
&lt;p&gt;A successful candidate will have experience in &lt;em&gt;in vivo&lt;/em&gt; immunology, proficiency in multicolor flow cytometry, fluorescence-activated cell sorting and a broad technique skill set, establishing and leveraging advanced disease models across a broad range of biology and leveraging cutting-edge multi-omics analytics to evaluate therapeutic efficacy. An ideal candidate would have experience in multiple areas of immunology, metabolism, cardiovascular, chronic &amp;amp; infectious disease, and oncology.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key responsibilities include:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Research, propose, and implement new disease models.&lt;/li&gt;
&lt;li&gt;Conduct and manage &lt;em&gt;in vivo&lt;/em&gt; immunology studies in house and via CROs, and ultimately broaden to multiple disease areas.&lt;/li&gt;
&lt;li&gt;Develop and conduct tissue analysis, such as flow cytometry, qPCR, ELISA etc.&lt;/li&gt;
&lt;li&gt;Collaborating closely with R&amp;amp;D team to design and build new molecular product hypotheses.&lt;/li&gt;
&lt;li&gt;Collaborate with Discovery team to enable new data generation activities.&lt;/li&gt;
&lt;li&gt;Execute&amp;nbsp;&lt;em&gt;in vivo&lt;/em&gt;&amp;nbsp;and&amp;nbsp;&lt;em&gt;in vitro&lt;/em&gt;&amp;nbsp;testing of molecular product candidates.&lt;/li&gt;
&lt;li&gt;Analysis, interpretation, documentation, and presentation of data to scientific and management team.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Ph.D. in immunology or related discipline, with 2-5+ years of industry research preferred&lt;/li&gt;
&lt;li&gt;Experience with multicolor flow cytometry, fluorescence-activated cell sorting, qPCR, western blot, cytokine/inflammatory mediator assessment, ELISA, and immunohistochemistry.&lt;/li&gt;
&lt;li&gt;Experience with &lt;em&gt;in vivo&lt;/em&gt; animal work, including various routes of administration (I.P., I.V., P.O., S.C.), blood collection by different routes, necropsy, and tissue collection.&lt;/li&gt;
&lt;li&gt;Demonstrated experience in selecting and developing new biology disease programs in Immunology. Experience in other key areas of interest including metabolism, mental health, cardiovascular diseases is preferred.&lt;/li&gt;
&lt;li&gt;Experience with broad set of molecular biology tools and analytical chemistry capabilities.&lt;/li&gt;
&lt;li&gt;Experience managing multiple projects and balancing broad set of ongoing priorities and activities in a fast-paced work environment.&lt;/li&gt;
&lt;li&gt;Highly motivated, self-driving and collaborative, be able to thrive in a fast-paced, action-oriented team environment and display a clear passion for science and impact.&lt;/li&gt;
&lt;li&gt;Strong verbal, written communication, and problem-solving skills.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Location: &lt;/strong&gt;Cambridge, MA&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;More About Flagship Pioneering&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Flagship Pioneering conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, the firm has, through its Flagship Labs unit, applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $50B in aggregate value. To date, Flagship has deployed over $2.2B in capital toward the founding and growth of its pioneering companies alongside more than $18B of follow-on investments from other institutions. The current Flagship ecosystem comprises 41 transformative companies, including Axcella Health (NASDAQ: AXLA), Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO), Foghorn Therapeutics (NASDAQ: FHTX), Indigo Ag, Kaleido Biosciences (NASDAQ: KLDO), Moderna (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology, Seres Therapeutics (NASDAQ: MCRB), and Sigilon Therapeutics (NASDAQ: SGTX).&lt;/p&gt;
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&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;Flagship Pioneering and our ecosystem companies are &lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/div&gt;
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&lt;/div&gt;
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&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

Scientist/Sr. Scientist - Translational Biology 

&lt;p&gt;&lt;strong&gt;Company Overview:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;FL92/93 Inc. is a privately held, well-funded, early-stage biotechnology company that is pioneering a novel transformative RNA-based therapeutic approach.&lt;/p&gt;
&lt;p&gt;FL92/93 was founded by Flagship Pioneering, a team of entrepreneurial scientists that conceives, creates, resources, and grows first-in-category life sciences companies. Since 2000, Flagship has created over 100 groundbreaking companies that are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna Therapeutics (NASDAQ:MRNA), Seres Therapeutics (NASDAQ:MCRB), Syros Pharmaceuticals (NASDAQ:SYRS), Rubius Therapeutics (NASDAQ:RUBY), Axcella Health (NASDAQ:AXLA), Evelo Biosciences (NASDAQ:EVLO), Laronde, Tessera, Alltrna, and Indigo Agriculture.&lt;/p&gt;
&lt;p&gt;FL92/93 Inc. is a highly dynamic, entrepreneurial, and innovation-driven organization seeking to hire an exceptional scientist to join our development team. FL92/93 is seeking a scientist with a strong background cell biology to join our expanding team as a part of our development group. The position requires broad technical experience that spans cellular biology and molecular biology, with a strong emphasis on critical thinking, multitasking, and the ability to learn new techniques. The successful candidate will help lead and support multidisciplinary project teams focused on the engineering and development of new therapeutic modalities, including nucleic acids, peptides, proteins, cells, and various conjugate molecules. The candidate will focus on all aspects of development spanning conceptualization, experimentation, data analysis, presentation, and strategic planning.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;The successful candidate will work both independently and as part of a team to design, plan and execute high-quality biochemical and cell-based assays&lt;/li&gt;
&lt;li&gt;Lead the development and execution of cell-based assays to assess the biological activity of nucleotide-based compounds&lt;/li&gt;
&lt;li&gt;Manage and oversee CRO collaborations for in vivo experiments&lt;/li&gt;
&lt;li&gt;Critical data analysis, attention to detail, and troubleshooting abilities&lt;/li&gt;
&lt;li&gt;Written and oral presentation of results&lt;/li&gt;
&lt;li&gt;Generate and support intellectual property generation for core projects&lt;/li&gt;
&lt;li&gt;Mentor and train research associates as needed&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Minimum Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Ph.D. in Cell Biology, Molecular Biology, Biochemistry, Bioengineering or related discipline with 0-4 years of experience in a biotech or pharmaceutical company (the title will be adjusted for the level of experience)&lt;/li&gt;
&lt;li&gt;Deep knowledge and understanding of cell biology. Proficient in experimental design, assay execution, troubleshooting, data analysis, and data interpretation&lt;/li&gt;
&lt;li&gt;Extensive hands-on experience in mammalian cell culture including primary cells and in handling tissues&lt;/li&gt;
&lt;li&gt;Strong expertise in flow cytometry, cell sorting and immunofluorescence (confocal microscopy preferred)&lt;/li&gt;
&lt;li&gt;The ideal candidate is experienced in RNA/DNA delivery (e.g., mRNA, siRNA, ASOs)&lt;/li&gt;
&lt;li&gt;Execution focused, team oriented, and highly motivated&lt;/li&gt;
&lt;li&gt;Experience with the following techniques is highly preferred: FISH, RT-qPCR, RNA-seq, cloning, cell culture, immunohistochemistry, Northern and Western blotting&lt;/li&gt;
&lt;/ul&gt;

FL92/93:  (Sr) Scientist – Cell Biology

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&lt;p&gt;&lt;strong&gt;Who we are&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Harbinger Health, a Flagship-founded company, is pioneering early cancer detection. Harbinger aims to detect cancer, at the earliest stages, to save lives. Our platform leverages proprietary biological insights and artificial intelligence to enable high-resolution, molecular views on cancer from blood. We are a highly dynamic, entrepreneurial, and innovation-driven organization seeking collaborative, passionate, and dedicated people to join our team.&lt;/p&gt;
&lt;p&gt;Flagship Pioneering conceives, creates, resources, and develops first-in-category bioplatform companies to transform human health and sustainability. Since its launch in 2000, the firm has, through its Flagship Labs unit, applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in more than $200 billion in aggregate value. To date, Flagship has deployed over $2.5 billion in capital toward the founding and growth of its pioneering companies alongside more than $19 billion of follow-on investments from other institutions. The current Flagship ecosystem comprises 42 transformative companies, including Axcella Health (Nasdaq: AXLA), Codiak BioSciences (Nasdaq: CDAK) Denali Therapeutics (Nasdaq: DNLI), Evelo Biosciences (Nasdaq: EVLO), Foghorn Therapeutics (Nasdaq: FHTX), Indigo Ag, Kaleido Biosciences (Nasdaq: KLDO), Moderna (Nasdaq: MRNA), Omega Therapeutics (Nasdaq: OMGA), Rubius Therapeutics (Nasdaq: RUBY), Sana Biotechnology (Nasdaq: SANA), Seres Therapeutics (Nasdaq: MCRB), and Sigilon Therapeutics (Nasdaq: SGTX).&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Harbinger Health is seeking a highly motivated and innovative Data Scientist to join our AI and Computational Biology group. The candidate will be responsible to create statistical models and machine learning models. In addition, the candidate will be responsible for analysis of raw data and model results. The candidate will also work on tools to help interpret and visualize raw data and model outputs. No prior knowledge of computational biology or experience in biotech industry is required. The candidate will be working closely with data scientists, machine learning engineers, bioinformatics group, and assay group. the candidate should have strong communication skills, attention to details and ability to work both independently and in a strong team environment.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key responsibilities&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Mine and analyze large data sets&lt;/li&gt;
&lt;li&gt;Preprocessing of data sets and data clean up&lt;/li&gt;
&lt;li&gt;Develop statistical and predictive models on genomic and health related data sets&lt;/li&gt;
&lt;li&gt;Analyze genomic data for feature selection&lt;/li&gt;
&lt;li&gt;Investigate data sets and machine learning models for potential biases and covariates&lt;/li&gt;
&lt;li&gt;Coordinate with different functional teams to implement models and monitor outcomes&lt;/li&gt;
&lt;li&gt;Develop processes and tools to assess model performance and accuracy&lt;/li&gt;
&lt;li&gt;Work with stakeholders throughout the organization&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Qualifications&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;PhD or MSc + 5 years of experience in Computer Science, Statistics, Computational Biology, Scientific Computing or other relevant areas&lt;/li&gt;
&lt;li&gt;Proficient in Python language&lt;/li&gt;
&lt;li&gt;Working experience with Python modules for data science: Pandas, Scikit-Learn, Scipy, Numpy&lt;/li&gt;
&lt;li&gt;Familiar with machine learning modules in python such as PyTorch or Keras&lt;/li&gt;
&lt;li&gt;Knowledge of advanced statistical techniques and concepts (properties of distributions, statistical tests, regression, etc.), and experience with applications&lt;/li&gt;
&lt;li&gt;Knowledge of variety of machine learning techniques (clustering, decision trees, artificial neural networks, etc.)&lt;/li&gt;
&lt;li&gt;Familiarity with genomic data types is a plus&lt;/li&gt;
&lt;li&gt;Strong problem solving skills&lt;/li&gt;
&lt;li&gt;Strong communication and collaboration skills&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;Flagship Pioneering and our ecosystem companies are&amp;nbsp;&lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt;&amp;nbsp;regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/p&gt;
&lt;p&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies:&lt;/strong&gt;&lt;/em&gt;&lt;em&gt;&amp;nbsp; Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates.&amp;nbsp; The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team.&amp;nbsp;&amp;nbsp; Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

Data Scientist/Sr. Data Scientist, AI and Computational Biology

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&lt;p&gt;&lt;strong&gt;Company Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Laronde is pioneering a platform that offers a completely novel way of modulating human biology. Endless RNA™ (eRNA), is a uniquely engineered RNA that can be programmed to express diverse proteins inside the body. It is long lasting, non-immunogenic, allows for repeat dosing, and offers flexibility in formulation and delivery.&lt;/p&gt;
&lt;p&gt;Laronde was founded in 2017 by Flagship Labs, the innovation foundry of Flagship Pioneering. Laronde has raised a record breaking $440 Million in a Series B Financing to advance the development of its eRNA platform. There is a broad pipeline of programs across therapeutic categories with the goal of 100 medicines in 10 years. To learn more, please visit the company’s website at &lt;a href=&quot;https://www.laronde.bio/about&quot;&gt;https://www.laronde.bio/about&lt;/a&gt;.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Laronde is seeking an enthusiastic Research Associate to join our expanding research team. The Research Associate will work closely with a Principal Scientist in the platform team to design and execute experiments to advance our novel RNA therapeutic platform. This role is located at our 2nd location at our brand new state of the art lab in Somerville, MA.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key Responsibilities&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Design, synthesize, and characterize novel large nucleic acid constructs for therapeutic applications&lt;/li&gt;
&lt;li&gt;Design, execute and troubleshoot biochemical and cell-based assays to evaluate nucleic acid potency&lt;/li&gt;
&lt;li&gt;Collaborate with the development team to develop and implement novel production methods&lt;/li&gt;
&lt;li&gt;Report experimental plans and results to the scientific team&lt;/li&gt;
&lt;li&gt;Proactively review literature to contribute to new ideas and technologies&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;B.S. or M.S. in Biology, Biochemistry or Molecular Biology or related field with 2+ years of laboratory research experience&lt;/li&gt;
&lt;li&gt;Strong experimental skills with experience in RNA biology, cell biology, molecular biology, biochemistry and/or assay development&lt;/li&gt;
&lt;li&gt;RNA biology skills including in vitro transcription and molecular biology techniques including PCR, qPCR, ELISA and Western blotting preferred&lt;/li&gt;
&lt;li&gt;Experience with mammalian cell culture and nucleic acid transfection are preferred&lt;/li&gt;
&lt;/ul&gt;
&lt;/div&gt;
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&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;Flagship Pioneering and our ecosystem companies are&amp;nbsp;&lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt;&amp;nbsp;regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;&amp;nbsp;&lt;/div&gt;
&lt;/div&gt;
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&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

Research Associate / Senior Research Associate, Molecular and Cellular Biology

&lt;p&gt;&lt;strong&gt;Company Details:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;FL92/93 Inc. is a privately held, well-funded, early-stage biotechnology company that is pioneering a novel transformative therapeutic approach.&lt;/p&gt;
&lt;p&gt;FL92/93 was founded by Flagship Pioneering, a team of entrepreneurial scientists that conceives, creates, resources, and grows first-in-category life sciences companies. Since 2000, Flagship has created over 100 groundbreaking companies that are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna Therapeutics (NASDAQ:MRNA), Seres Therapeutics (NASDAQ:MCRB), Syros Pharmaceuticals (NASDAQ:SYRS), Rubius Therapeutics (NASDAQ:RUBY), Axcella Health (NASDAQ:AXLA), Evelo Biosciences (NASDAQ:EVLO), Laronde, Tessera, Alltrna, and Indigo Agriculture.&lt;/p&gt;
&lt;p&gt;FL92/93 Inc. is a highly dynamic, entrepreneurial, and innovation-driven organization seeking to hire an exceptional RNA principal scientist to join our development team. FL92/93 is seeking a scientist with a strong background in nucleic acid manipulation and delivery strategies to join our expanding team as a part of our development group. The position requires broad technical experience that spans molecular biology, synthetic biology, and biophysics, with a strong emphasis on critical thinking, multitasking, and the ability to learn new techniques. The successful candidate will help lead and support multidisciplinary project teams focused on the engineering and development of new therapeutic modalities, including nucleic acids, peptides, proteins, cells, and various conjugate molecules. The candidate will focus on all aspects of development spanning conceptualization, experimentation, data analysis, presentation, and strategic planning.&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Nucleic acid manipulation, modification, and analytic approaches&lt;/li&gt;
&lt;li&gt;Viral and non-viral nucleic acid formulation and delivery&lt;/li&gt;
&lt;li&gt;Quantitative analysis of biological molecules&lt;/li&gt;
&lt;li&gt;Critical data analysis, attention to detail, and troubleshooting abilities&lt;/li&gt;
&lt;li&gt;Written and oral presentation of results&lt;/li&gt;
&lt;li&gt;Manage and oversee CROs, providing technical expertise and direction on production and characterization activities&lt;/li&gt;
&lt;li&gt;Manage research associates and scientists&lt;/li&gt;
&lt;li&gt;Generate and support intellectual property generation for core projects&lt;/li&gt;
&lt;li&gt;Mentor and train research associates as needed&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Minimum Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Ph.D. in Molecular Biology, Biochemistry, Bioengineering or related discipline and 5+ years of industry experience&lt;/li&gt;
&lt;li&gt;Deep knowledge and understanding of RNA biology. Proficient in experimental design, assay execution, troubleshooting, data analysis, and data interpretation&lt;/li&gt;
&lt;li&gt;Strong expertise in RNA biochemistry and RNA structural biology&lt;/li&gt;
&lt;li&gt;Strong experience in ASO design&lt;/li&gt;
&lt;li&gt;Skilled in assay development and optimization of nucleic acid production, purification and biophysical characterization&lt;/li&gt;
&lt;li&gt;Expertise in NGS library preparation, RNA seq and analysis of RNA binding protein interactions preferred&lt;/li&gt;
&lt;li&gt;Execution focused, team oriented, and highly motivated&lt;/li&gt;
&lt;li&gt;Experience with the following techniques is highly preferred: RT-qPCR, RNA-seq, cloning, cell culture, immunohistochemistry, ELISA, ChIP, EMSA, FISH, Northern and Western blotting&lt;/li&gt;
&lt;/ul&gt;

FL92/93: Principal Scientist – RNA Biology

&lt;p&gt;&lt;strong&gt;Company Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Laronde is pioneering a platform that offers a completely novel way of modulating human biology. Endless RNA™ (eRNA), is a uniquely engineered RNA that can be programmed to express diverse proteins inside the body. It is long lasting, non-immunogenic, allows for repeat dosing, and offers flexibility in formulation and delivery.&lt;/p&gt;
&lt;p&gt;Laronde was founded in 2017 by Flagship Labs, the innovation foundry of Flagship Pioneering. Laronde has raised a record breaking $440 Million in a Series B Financing to advance the development of its eRNA platform. There is a broad pipeline across therapeutic categories with the goal of 100 medicines in 10 years. To learn more, please visit the company’s website at https://www.laronde.bio/about.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Laronde is seeking a creative, motivated Associate Scientist to join the Analytical Development team supporting our eRNA platform. &amp;nbsp;We are searching for driven, enthusiastic and self-motivated individuals who are comfortable multitasking, collaborating, and working independently on various aspects of the platform.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Identify, evaluate, and implement new methods and technologies to support the Laronde platform and projects&lt;/li&gt;
&lt;li&gt;Develop eRNA, LNP, and lipid methods intended for a variety of purposes, including release and stability testing, product characterization, and high throughput analysis&lt;/li&gt;
&lt;li&gt;Work cross-functionally to plan and execute complex characterization studies&lt;/li&gt;
&lt;li&gt;Oversee troubleshooting, tech transfer, and phase-appropriate validation of analytical methods at contract testing labs&lt;/li&gt;
&lt;li&gt;Review, interpret, and present data within the analytical team and cross-functionally&lt;/li&gt;
&lt;li&gt;Author and review technical reports&lt;strong&gt;&amp;nbsp;&lt;/strong&gt;and regulatory submissions&lt;/li&gt;
&lt;li&gt;Train and mentor junior team members&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;&amp;nbsp;Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Bachelors and 8+ or Masters and 6+ years of experience&lt;/li&gt;
&lt;li&gt;Experience with one of the following:&lt;/li&gt;
&lt;ul&gt;
&lt;li&gt;Chromatography, capillary electrophoresis, and/or mass spectrometry (lipid expertise is a plus)&lt;/li&gt;
&lt;li&gt;Cell based assay and ELISA experience&lt;/li&gt;
&lt;/ul&gt;
&lt;li&gt;Ability to work independently and within a team&lt;/li&gt;
&lt;li&gt;Excellent communication skills; proficiency in good documentation practices and data analysis and reporting&lt;/li&gt;
&lt;li&gt;Demonstrated ability to achieve in a fast-paced and entrepreneurial environment&lt;/li&gt;
&lt;li&gt;Experience developing therapeutics-focused technology platforms a strong plus&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;em&gt;Laronde is &lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;&lt;/em&gt;&lt;em&gt;: Laronde does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Laronde or its employees is strictly prohibited unless contacted directly by Laronde’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Laronde, and Laronde will not owe any referral or other fees with respect thereto&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;

Associate Scientist, Analytical Development (Bioassay or Chromatography)

&lt;p&gt;&lt;strong&gt;Scientist / Senior Scientist, In vitro Biology&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;What if…&lt;/strong&gt; you could join an organization that is discovering and developing an entirely new class of medicines, one that leverages both chemistry and biology, to overcome many of the challenges faced by current therapeutics today?&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Company Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Flagship Labs 83, Inc. (FL83) is a privately held, early-stage biotechnology company on a mission to make biology better through chemistry. We are pioneering the development of a transformational new class of medicines, called Artificial Biologics&lt;sup&gt;TM&lt;/sup&gt;, that is unlocked by novel synthetic and computational technologies. We seek an exceptional In Vitro Biologist to join our entrepreneurial and innovation-driven organization.&lt;/p&gt;
&lt;p&gt;FL83 was founded in Flagship Pioneering’s venture creation engine, where companies such as Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY) and Generate Biomedicines were conceived and created. Since Flagship’s founding in 2000, the firm has originated and fostered the development of more than 100 scientific ventures resulting in over $34 billion in aggregate value, more than 500 issued patents and more than 50 clinical trials for novel therapeutic agents.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position summary&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Flagship Labs 83 is looking for a creative and motivated &lt;strong&gt;Scientist or Senior Scientist, &lt;/strong&gt;specializing in biochemistry&lt;strong&gt; &lt;/strong&gt;to build our Artificial Biologics&lt;sup&gt;TM&lt;/sup&gt; biology team. As part of the founding scientific team, this individual will be instrumental in building the biology platform, using in vitro studies to screen and characterize Artificial Biologics&lt;sup&gt;TM&lt;/sup&gt; libraries, with the aim to develop impactful new therapeutics. This individual will have experience in peptide and protein discovery ideally including both molecular and cellular biology. A successful candidate will be an excellent collaborator working closely with our Computational Protein Design, and Platform Development teams to implement and execute rapid design-build-test iteration cycles and optimized methods.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key Responsibilities&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Design and execute hit-to-lead&lt;em&gt; &lt;/em&gt;experiments for peptides, proteins, and biopolymer libraries (Artificial Biologics&lt;sup&gt;TM&lt;/sup&gt;)&lt;/li&gt;
&lt;li&gt;Perform cellular/molecular biology techniques including immune, metabolic, enzymatic and signaling cell-based assays (eg. GPCR activation)&lt;/li&gt;
&lt;li&gt;Perform medium and high throughput assays including ELISA, SPR, FP, TR-FRET, and biopanning (i.e. phage display)&lt;/li&gt;
&lt;li&gt;Design, develop, optimize and execute in vitro assays such as Western blots, Coomassie blue staining, MSD, RT-PCR, qPCR, and flow cytometry, etc.&lt;/li&gt;
&lt;li&gt;Perform statistical analysis of results and prepare figures for discussion&lt;/li&gt;
&lt;li&gt;Document high quality results in an electronic laboratory notebook, and present and share with the broader team of scientists and leadership&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Qualifications&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;PhD or MS in cellular biology, molecular biology, immunology, neurobiology or related discipline, with 2-5+ years of industry research preferred&lt;/li&gt;
&lt;li&gt;Driven to develop a transformative therapeutic discovery and target validation platform&lt;/li&gt;
&lt;li&gt;Experience executing on various cell-based disease models across target disease areas (eg. DiscoverX assays)&lt;/li&gt;
&lt;li&gt;Demonstrated industry experience or academic achievement, as evidenced by publications in high impact journals and conference proceedings&lt;/li&gt;
&lt;li&gt;Excellent communication and presentation skills, capable of conveying technical information in a clear and thorough manner&lt;/li&gt;
&lt;li&gt;Demonstrated ability to work with highly skilled, intellectually diverse teams in an industry environment&lt;/li&gt;
&lt;li&gt;Experience with receptor-ligand assays, signal transduction assays, and/or cytokine/chemokine/growth factor biology a plus&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;Flagship Pioneering and our ecosystem companies are&amp;nbsp;&lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt;&amp;nbsp;regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;*: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.*&lt;/p&gt;

Data Scientist Jobs in Cambridge