2026_155_CLINICAL Data Manager - Grenba

JOB DESCRIPTION

The Institut d’Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP) is seeking
to incorporate a Clinical Data Manager to work on the INTEGRA-DM1 and DM1 Hub
project database, the largest clinical registry of patients with Myotonic Dystrophy Type
1 (DM1) in Spain.

INTEGRA-DM1 is a complex multiomics project and DM1-Hub is a national clinical
registry and research platform that supports clinical research, translational studies, and
real world evidence generation in DM1. Due to the growing volume and complexity of
the data, we currently need a professional with a transversal vision and strong analytical
capacity to process and analyse clinical data in order to support strategic decision
making, while responding to the evolving needs of the research group. The selected
candidate will lead the development of a digital application to enable the prospective
follow-up of patients, contributing to the construction of a natural history registry of the
disease through the systematic collection of a wide range of Patient Reported Outcome
Measures (PROMs). In addition, the selected candidate will give support to the ongoing
long-read genomic data analyses and lead exploratory studies combining omics and
clinical data in order to better characterize the generated DM1-INTEGRA data and the
existing DM1 cohort of the registry.

MAIN RESPONSIBILITIES

a) Lead the processing, analysis, and interpretation of data from INTEGRA-DM1
and the DM1-Hub project database. Developing of graphical user interfaces
(GUIs).
b) Building and maintaining pipelines, coding in Nextflow, R, Python, and Bash.
c) Apply a transversal and integrative analytical approach to support strategic
decision making related to the evolution and sustainability.
d) Respond to data-related needs of the research group, translating clinical and
scientific questions into analytical solutions.
e) Ensure data quality, harmonisation, standardisation, and interoperability of
clinical datasets.
f) Design and lead the development of a digital application for prospective patient
follow-up, enabling systematic data capture over time.
g) Implement and analyse a wide range of Patient Reported Outcome Measures
(PROMs) to support the study of the natural history of DM1.
h) Generate reports, visualisations, and scientific outputs for internal decision
making, publications, and project deliverables.
i) Ensure compliance with ethical, regulatory, and data protection requirements
related to clinical research data.

QUALIFICATIONS AND EXPERIENCE

a) PhD in (Bio)informatics, Data Science, Biomedical Sciences, Computational Biology, or
related disciplines.
b) Strong background in (bio)informatics and large-scale clinical and omics data analysis,
especially genomics (long-read) and proteomics.
c) Demonstrated experience in processing, integrating, and analysing complex clinical or
biomedical datasets.
d) Experience in designing and developing web and/or mobile applications (TRL 1-5),
preferably in a clinical or healthcare research environment.
e) Proficiency in data analysis, workflow architecture tools (Nextflow, Snakemake) and
programming tools (e.g. R, Python, SQL or similar).
f) Excellent written and spoken English and Spanish; knowledge of Catalan will be
valued.
g) Strategic mindset, strong problem-solving skills, autonomy, and ability to collaborate
in multidisciplinary teams.

WHAT WE OFFER

• Type of contract and working hours: Permanent, full-time employment contract (under the Spanish Science Law / Ley de la Ciencia). 
• 1 of January 2027.
• 38.000 €/year.
• Flexible payment (childminding vouchers).
• 23 days holiday and 5 days for personal matters.
• Training capsules by the company.
• Be part of an excellent multidisciplinary research centre with the HRS4R badge.
• Location on the Can Ruti Campus, a first-class translational research environment in the Barcelona area, in a very stimulating scientific environment.
• The IGTP offers a supportive, friendly and collaborative ecosystem to promote professional development and help you achieve your research goals.

FOR MORE INFORMATION

• www.dm1spain.com
• https://www.germanstrias.org/es/research/neurociencias/5/grupo-de-investigacionen-enfermedades-neuromusculares-de-badalona-grenba

RESOLUCION

HOW TO APPLY

Interested persons must attach to the application:

• Motivation letter explaining their interest in the position.
• Updated CV.
• Contact of 2-3 references.

Applications will be evaluated in accordance with the guiding principles and objectives of the supply systems, following the process described below:

Curricular evaluation: analysis of the curriculum vitae to assess aspects related to training, professional career and experience in positions related to the job position under selection.

Personal interview: once the résumé has been evaluated, the selected candidates will be called for a personal interview to verify and expand on the information detailed in the résumé and to evaluate aspects related to experience and professional skills.

Applications that do not meet the requirements, that are not included in the cases foreseen or that are not processed in accordance with the established procedure will not be considered in the selection process.

DEADLINE FOR APPLICATIONS

The call for applications will close on 23th November 2026.