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Director, AI ML and Cloud Security

Pay
$168,750–281,250/year · Base — pay source
AI for Cybersecurity, Application Security, Cloud Security, Computer Programming, Data Security, Identity Access Management (IAM), Information Systems, Infrastructure Security, ML Security, Operating Systems Security, Scripting, Security Engineering, Security Technologies, Security Testing, Vulnerability Management The US annual base salary for new hires in this position ranges from $168,750 to $281,250. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process. Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.
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Work setting
Not stated
Employment
Full-time — employment source
Employment type in the employer’s posting: Full time
From the employer’s posting

What you’ll work on

Full posting

Own all AI architecture for Cyber Architecture and Solutions — the designs that AI Engineering builds and a managed service vendor operates.

  • Act as design authority, approving or rejecting every AI solution build before engineering starts

  • Own agentic framework architecture, including tool control, identity binding and least-privilege scoping

  • Own the data fabric architecture, covering data flows, classification and controls

  • Own the AI reference design and pattern library used by engineering and the vendor

  • Lead three architects covering solution architecture, standards and governance

From the employer’s posting
Own all AI architecture for Cyber Architecture and Solutions — the designs that AI Engineering builds and a managed service vendor operates. You are the design authority for the agentic framework and the data fabric: nothing is built without a specification from your team. You lead three architects and carry architecture accountability across design, build and vendor operation.
Act as design authority for every AI solution Cyber Architecture and Solutions builds
Own the agentic framework architecture: agent orchestration, tool invocation control, identity binding, least-privilege scoping, human-in-the-loop gates and trust boundaries.
Own the data fabric architecture — what data flows where, at what classification, under what controls, and how the fabric evolves as the vendor introduces agentic capability.
Own the AI reference design and pattern library that Engineering and the vendor build against.
Lead three architects covering solution architecture, standards and governance.
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Posting record

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Actively hiringFirst seen by us today, still listed, and not a repost of an earlier posting.

Status in our records
Live
First seen by us
Nov 3, 2026today
Recorded sightings
2
Last seen by us
Nov 4, 2026

These dates show when we found the posting. Check the employer’s website to confirm it is still accepting applications.

How this job compares

Pay

In line with similar jobs

$169K–$281K against $154K–$225K, the middle half of what similar US postings state.

From 2,958 postings in the last year. Stated ranges, not salaries paid.

Time since we first saw it

Day 0

Early. Similar jobs usually come down between day 7 and day 53.

From 7,797 similar postings that came down. Coming down is not always a hire.

GSK is hiring

27 open jobs

Open jobs by the week we first saw them, last 12 weeks.

  • Data Leadership hiring is picking up
  • Takes jobs down at a usual pace
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  • Python
  • Azure
  • GCP
  • Kubernetes
Where the posting names them
Preferred Qualification If you have the following characteristics, it would be a plus: - Working understanding of LangChain or LlamaIndex, vector databases, production Python and Kubernetes - AI use-case feasibility assessment and risk-based prioritisation before engineering build
Own all AI architecture for Cyber Architecture and Solutions — the designs that AI Engineering builds and a managed service vendor operates. You are the design authority for the agentic framework and the data fabric: nothing is built without a specification from your team. You lead three architects and carry architecture accountability across design, build and vendor operation. About the team. AI ML and Cloud Security is the function through which GSK is transforming security itself. The team designs and builds the agentic framework, a multi-agent platform moving security services across the Chief Security Office from rule-based to AI-driven operation. It owns AI architecture and AI engineering end to end: the agent layer, LLM orchestration, the AI and ML platform, and the data fabric pipeline that Cyber Architecture and Solutions designs, builds and tests before a managed service vendor operates it. The team also governs AI tool security posture, advises on cloud security across the Azure and GCP estate, and is the front door between GSK's business units and R&D and the technical AI function. AI security standards set here are binding on every AI initiative in GSK. Seventeen roles across the UK, India and the US. What makes this role different. This is a design authority role, not an AI governance role. You will personally own the agentic framework architecture — agent orchestration, tool invocation, identity binding, least-privilege scoping — and the data fabric design that determines what data flows where, at what classification, under what controls. Expect to whiteboard an agentic or RAG architecture you designed and defend the trade-offs. If your AI background is policy frameworks and vendor assessment rather than designs that were built, this will not suit you.

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Has GSK posted this job before?

Yes. We’ve followed 2 other Director, AI ML and Cloud Security jobs there since October 2026. All 2 are still up.

  1. New Oxford StreetStill up after 12 days, first seen Oct 23
  2. New Oxford StreetStill up after 12 days, first seen Oct 23
  3. This jobUp 1 day so far, first seen Nov 3

Job description

View original posting ↗

Business Introduction


GSK remains committed to achieving bold commercial ambitions for the future. By 2031, we aim to deliver £40 billion in annual sales, leveraging our existing strong performance momentum to significantly increase our positive impact on the health of billions of patients globally. Our Ahead Together strategy is centred on early intervention to prevent and alter the course of disease, thereby protecting people and supporting healthcare systems.
Our diverse portfolio consists of vaccines, specialty medicines, and general medicines.
Through continuous innovation and a dedicated focus on scientific and technical excellence, we strive to develop and launch new, groundbreaking treatments that address critical health challenges.

Domain focus: AI Architecture (agentic framework, data fabric architecture and AI solution blueprints); design authority for enterprise AI/ML.


Position Summary


Own all AI architecture for Cyber Architecture and Solutions — the designs that AI Engineering builds and a managed service vendor operates. You are the design authority for the agentic framework and the data fabric: nothing is built without a specification from your team. You lead three architects and carry architecture accountability across design, build and vendor operation. 

About the team. AI ML and Cloud Security is the function through which GSK is transforming security itself. The team designs and builds the agentic framework, a multi-agent platform moving security services across the Chief Security Office from rule-based to AI-driven operation. It owns AI architecture and AI engineering end to end: the agent layer, LLM orchestration, the AI and ML platform, and the data fabric pipeline that Cyber Architecture and Solutions designs, builds and tests before a managed service vendor operates it. The team also governs AI tool security posture, advises on cloud security across the Azure and GCP estate, and is the front door between GSK's business units and R&D and the technical AI function. AI security standards set here are binding on every AI initiative in GSK. Seventeen roles across the UK, India and the US. 


What makes this role different. This is a design authority role, not an AI governance role. You will personally own the agentic framework architecture — agent orchestration, tool invocation, identity binding, least-privilege scoping — and the data fabric design that determines what data flows where, at what classification, under what controls. Expect to whiteboard an agentic or RAG architecture you designed and defend the trade-offs. If your AI background is policy frameworks and vendor assessment rather than designs that were built, this will not suit you. 



Responsibilities


This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

  • Act as design authority for every AI solution Cyber Architecture and Solutions builds; nothing enters engineering without a specification from this team. 
  • Own the agentic framework architecture: agent orchestration, tool invocation control, identity binding, least-privilege scoping, human-in-the-loop gates and trust boundaries. 
  • Own the data fabric architecture — what data flows where, at what classification, under what controls, and how the fabric evolves as the vendor introduces agentic capability. 
  • Own the AI reference design and pattern library that Engineering and the vendor build against. 
  • Lead three architects covering solution architecture, standards and governance. 
  • Chair the design authority board where every Cyber Architecture and Solutions AI build is approved or sent back before engineering capacity is allocated. 
  • Assess new AI tool proposals for architectural fit and reject what does not conform. 
  • Rule on feasibility for the highest-risk R&D and business AI proposals that AI Business Facing escalates to you. 
  • Assure vendor handover packages and retain architecture accountability once the vendor operates the solution. 
  • Set the architecture decision record template and arbitrate the decisions it captures, so design rationale stays traceable for audit and regulatory inspection. 


Why You?

Basic Qualification


We are seeking professionals with the following required skills and qualifications to help us achieve our goals:

  • 12+ years of experience in cybersecurity or AI architecture, including experience leading technical teams across geographies, with expertise in AI architecture, including agentic frameworks, data fabric architecture, AI solution blueprints, and design authority for enterprise AI/ML solutions.
  • Experience designing agentic frameworks, multi-agent systems, and Retrieval-Augmented Generation (RAG) architectures, including agent design patterns, trust models, orchestration, tool-calling boundaries, identity binding, least-privilege tool scoping, human-in-the-loop approvals, containment, kill switches, and rollback mechanisms.
  • Experience designing data fabric architectures, including defining how data flows across systems, data classification requirements, applicable controls, and how these architectures evolve as agentic capabilities are introduced.
  • Experience developing AI solution blueprints for security use cases, including GenAI alert triage, automated investigations, threat summarization, and AI-driven workflows, with experience establishing model and platform selection criteria across hosted and self-hosted LLMs, embeddings, vector stores, and orchestration platforms based on security, cost, latency, and data residency requirements.
  • Experience incorporating AI security standards and threat modeling into solution design, including frameworks and standards such as the EU AI Act, NIST AI Risk Management Framework (AI RMF), and ISO/IEC 42001, and translating these requirements into technical specifications for engineering teams.

Preferred Qualification
If you have the following characteristics, it would be a plus:

  • Working understanding of LangChain or LlamaIndex, vector databases, production Python and Kubernetes 
  • AI use-case feasibility assessment and risk-based prioritisation before engineering build 
  • Architecture quality review and standards governance 
  • Regulated industry experience, including GxP and data integrity requirements applied to AI 
  • North American AI architecture coverage and R&D pipeline engagement (US-based role)

#GSK-LI

#AGTech


Skills

AI for Cybersecurity, Application Security, Cloud Security, Computer Programming, Data Security, Identity Access Management (IAM), Information Systems, Infrastructure Security, ML Security, Operating Systems Security, Scripting, Security Engineering, Security Technologies, Security Testing, Vulnerability Management

 

 

The US annual base salary for new hires in this position ranges from $168,750 to $281,250. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.

Please visit  GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - usrecruitment.adjustments@gsk.com

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

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