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Lead Software Platform Engineer, MLOps

Cambridge, Massachusetts, United States

Live, first seen by us 89 days ago
Pay
USD 200,000–270,000/yearAnnual period assumed — pay source
A culture of continuous improvement where you can grow your career and get coaching The salary range for this position is $200K-$270K USD. The salary range posted reflects our target baseline for this role. Final compensation is determined by a thorough evaluation of factors including the candidate’s specific experience, localized market data, and internal team equity. We are not currently providing visa sponsorship for this position.
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Work setting
On-site — work setting source
Work setup in the employer’s posting: On-site
From the employer’s posting
Employment
Not stated

Before you apply

Work authorization
Must already have the right to workWe are not currently providing visa sponsorship for this position

What you’ll work on

Full posting
  • Own the architecture of the AI/ML platform service and API surface used by customers and internal teams

  • Own the model and prompt lifecycle across Databricks MLflow and AWS Bedrock, including staged promotion and rollback

  • Design the inference substrate for real-time and batch AI workloads, including routing, batching and caching

  • Build security controls for prompts, retrieval and tool calls, including hard tenant data boundaries

  • Build evaluation, regression gating and production observability for AI systems

From the employer’s posting
Own the technical architecture of the AI/ML platform
Own the end-to-end model and prompt lifecycle across Databricks MLflow and AWS Bedrock, including registration, versioning, asset bundles, staged promotion, rollback, and multi-model serving.
Design the inference substrate for both real-time and batch AI workloads, including routing, batching, caching, concurrency control
Design security into the AI platform rather than leaving it to the applications above it
Build the evaluation and quality infrastructure that makes AI shippable

What you’ll bring

All qualifications

Core experience

  • 10+ years of professional experience in software engineering and infrastructure engineering, with a proven track record of designing, building, and scaling distributed, cloud-native systems in production.
  • Familiarity with emerging LLM frameworks for advanced prompt orchestration and programmatic LLM pipelines.
  • Demonstrated experience as a technical leader or architect, accountable for the key decisions on system design, scalability, performance, and cost optimization.
  • Experience running agentic or multi-step orchestration in production, and with MCP as an integration surface for tooling and non-human identities.
  • Experience designing security into a multi-tenant platform, including authorization boundaries between tenants and handling of sensitive data such as PII and PHI, with awareness of LLM-specific risks like prompt injection and tool abuse.
  • Understanding of LLM cost monitoring, latency optimization, and usage analytics in production environments, including per-tenant cost attribution for tokens, GPU, and inference.
Qualification wording
10+ years of professional experience in software engineering and infrastructure engineering, with a proven track record of designing, building, and scaling distributed, cloud-native systems in production.
Familiarity with emerging LLM frameworks for advanced prompt orchestration and programmatic LLM pipelines.
Demonstrated experience as a technical leader or architect, accountable for the key decisions on system design, scalability, performance, and cost optimization.
Experience running agentic or multi-step orchestration in production, and with MCP as an integration surface for tooling and non-human identities.
Experience designing security into a multi-tenant platform, including authorization boundaries between tenants and handling of sensitive data such as PII and PHI, with awareness of LLM-specific risks like prompt injection and tool abuse.
Understanding of LLM cost monitoring, latency optimization, and usage analytics in production environments, including per-tenant cost attribution for tokens, GPU, and inference.

Benefits in the posting

Full benefits wording
  • 100% employer-paid benefits for all eligible employees and immediate family members
  • Unlimited paid time off (PTO)
  • 401K

From the employer’s posting.

About TetraScience

TetraScience is the Scientific Data and AI Cloud company.

In the employer’s words · Read in context

Apply at TetraScience

Posting record

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Status in our records
Live
First seen by us
Aug 7, 202689 days ago
Recorded sightings
40
Last seen by us
Nov 4, 2026

These dates show when we found the posting. Check the employer’s website to confirm it is still accepting applications.

How this job compares

Pay

In line with similar jobs

$200K–$270K against $166K–$240K, the middle half of what similar US postings state.

From 1,279 postings in the last year. Stated ranges, not salaries paid.

Time since we first saw it

Day 89

Up longer than most. Similar jobs usually come down between day 6 and day 69.

From 4,381 similar postings that came down. Coming down is not always a hire.

TetraScience is hiring

10 open jobs

Open jobs by the week we first saw them, last 12 weeks.

  • Hiring at a steady pace
  • Takes jobs down at a usual pace
  • 10% of open jobs were reposted
Hiring record

See how this role fits your experience

Add your resume and we’ll mark which of these tools you already use, and point out anything in the posting that could rule you out.

  • Python
  • TypeScript
  • AWS
  • Databricks
  • Docker
  • MLflow
Where the posting names them
- Deep, hands-on experience taking LLM-based systems to production, including RAG architecture, retrieval and embedding design, prompt and model versioning, and tool or function calling. Not just prototyping with an SDK. We are looking for someone who has operated these systems under real traffic, real latency budgets, and real failure modes. - Expert-level coding skills in TypeScript and Python building robust APIs and backend services, with the judgment to critically evaluate AI-generated code for correctness, security, and architectural fit. - Production-level experience with a model registry and serving stack, ideally Databricks MLflow, including model registration, versioning, asset bundles, and serving workflows.
- Own the technical architecture of the AI/ML platform: the service and API surface our customers use to run models and agents against their own scientific data, and that Applied AI and data engineering teams build against internally. - Own the end-to-end model and prompt lifecycle across Databricks MLflow and AWS Bedrock, including registration, versioning, asset bundles, staged promotion, rollback, and multi-model serving. - Design the inference substrate for both real-time and batch AI workloads, including routing, batching, caching, concurrency control, GPU and accelerator capacity planning, handling of large binary inputs such as instrument images, and graceful degradation under load.
- Design for reproducibility and lineage required in a validated pharma environment, with versioned data, code, prompts, and model artifacts, and an audit trail that can withstand customer and regulatory scrutiny. - Contribute to the infrastructure-as-code and deployment automation for the AI platform (CloudFormation, AWS CDK), partnering with the team that owns production deployments to support multi-tenant infrastructure, online upgrades, and on-demand compute allocation. - Own production readiness for the AI platform with Applied AI engineers, data engineers, and platform teams: the performance, reliability, and cost-efficiency of models in production, plus incident response and runbooks.
- Proficiency in API-first design, including REST and OpenAPI specifications, designing APIs that are scalable, secure, versioned, and extensible. - Solid working knowledge of AWS and containerized workloads (e.g., Docker), and familiarity with infrastructure-as-code such as CloudFormation or CDK, with the ability to contribute to CI/CD pipelines and deployment automation. - Experience defining observability and SLI/SLO/SLA practice for production systems, including monitoring, alerting, and distributed tracing.
- Expert-level coding skills in TypeScript and Python building robust APIs and backend services, with the judgment to critically evaluate AI-generated code for correctness, security, and architectural fit. - Production-level experience with a model registry and serving stack, ideally Databricks MLflow, including model registration, versioning, asset bundles, and serving workflows. - Experience treating AI evaluation as a release gate rather than post-hoc reporting, including eval harnesses, regression gates, and drift or quality monitoring for non-deterministic systems.

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About the role

We file this job under ML Engineer, by the work the posting describes.

ML engineers put machine learning models into products. They write the code that trains, ships, serves and monitors models so a recommendation or prediction works for real users.

Postings ask for strong Python and software engineering, a framework such as PyTorch, cloud services, and more and more often experience with large language models.

A data scientist often works out which model to build; an ML engineer makes it run reliably in production.

US government figures for computer and information research scientists

Median yearly pay, May 2025
$140,300
Expected change, 2025 to 2035
21.8% more jobsagainst 3.5% for all jobs

The government has no code for ML engineers, so these figures are for the closest group, computer and information research scientists.

Source: US Bureau of Labor Statistics, Occupational Employment and Wage Statistics (May 2025) and Employment Projections (2025 to 2035). Occupation code 15-1221.

Job description

View original posting ↗

Who We Are

TetraScience is the Scientific Data and AI Cloud company. We are catalyzing the Scientific AI revolution by designing and industrializing AI-native scientific data sets, which we bring to life in a growing suite of next gen lab data management solutions, scientific use cases, and AI-enabled outcomes.

TetraScience is the category leader in this vital new market, generating more revenue than all other companies in the aggregate. In the last year alone, the world's dominant players in compute, cloud, data, and AI infrastructure have converged on TetraScience as the de facto standard, entering into co-innovation and go-to-market partnerships.

In connection with your candidacy, you will be asked to carefully review the Tetra Way letter, authored directly by Patrick Grady, our co-founder and CEO. This letter is designed to assist you in better understanding whether TetraScience is the right fit for you from a values and ethos perspective.

It is impossible to overstate the importance of this document and you are encouraged to take it literally and reflect on whether you are aligned with our unique approach to company and team building. If you join us, you will be expected to embody its contents each day.

The Role

We're looking for a Lead Software Platform Engineer working at the intersection of distributed systems and MLOps. You will own and scale our AI and data infrastructure as a product our customers build their science on, and that every other engineering team builds against. You will architect the cloud-based services and MLOps infrastructure that enable production-grade AI/ML workflows, working closely with Applied AI engineers, data engineers, and platform teams, and you will act as the technical design authority for how models, LLMs, and agents run in production. The work spans the model and prompt lifecycle, the evaluation and observability harness, the security and tenant boundaries around prompts and retrieval, and the cost and latency controls that keep production AI economically viable at scale.

This is a highly impactful seat for an engineer who has shipped AI/ML infrastructure as a multi-tenant product rather than internal tooling. The model serving, MCP, and agent capabilities you build are consumed directly by scientists at the world's largest pharmaceutical companies, running against their own data under their compliance obligations. If that scope appeals to you, and you thrive on turning ambitious scalability and cost targets into concrete technical strategy inside a regulated environment, we'd love to talk to you.

What You Will Do

  • Own the technical architecture of the AI/ML platform: the service and API surface our customers use to run models and agents against their own scientific data, and that Applied AI and data engineering teams build against internally.
  • Own the end-to-end model and prompt lifecycle across Databricks MLflow and AWS Bedrock, including registration, versioning, asset bundles, staged promotion, rollback, and multi-model serving.
  • Design the inference substrate for both real-time and batch AI workloads, including routing, batching, caching, concurrency control, GPU and accelerator capacity planning, handling of large binary inputs such as instrument images, and graceful degradation under load.
  • Integrate AI models and large language models (LLMs) into production systems using architectures like retrieval-augmented generation (RAG), and architect the agentic layer above them: tool and function calling, MCP-based tooling, and agent runtimes, deciding what belongs in the platform versus in the applications built on top of it.
  • Design security into the AI platform rather than leaving it to the applications above it, partnering with our security team on guardrails, prompt-injection and tool-abuse defenses, PII and PHI handling, and hard tenant data boundaries across prompts, retrieval, and tool calls.
  • Build the evaluation and quality infrastructure that makes AI shippable: offline and online eval harnesses, golden datasets, regression gates in CI, A/B and shadow deployment, and drift and hallucination detection in production.
  • Establish observability for the AI platform, including monitoring, alerting, logging, and distributed tracing, and set the SLI, SLO, and SLA model for systems whose outputs are probabilistic.
  • Design for reproducibility and lineage required in a validated pharma environment, with versioned data, code, prompts, and model artifacts, and an audit trail that can withstand customer and regulatory scrutiny.
  • Contribute to the infrastructure-as-code and deployment automation for the AI platform (CloudFormation, AWS CDK), partnering with the team that owns production deployments to support multi-tenant infrastructure, online upgrades, and on-demand compute allocation.
  • Own production readiness for the AI platform with Applied AI engineers, data engineers, and platform teams: the performance, reliability, and cost-efficiency of models in production, plus incident response and runbooks.
  • Act as SME and design authority across product and engineering. Lead design reviews, write the reference architectures and technical documentation others follow, and mentor senior and mid-level engineers on distributed systems and AI engineering practice.
  • Set technical direction on emerging AI infrastructure: evaluate new frameworks, serving runtimes, model providers, and data types, and make clear build-versus-buy decisions grounded in cost, risk, and scalability.

Requirements

    • 10+ years of professional experience in software engineering and infrastructure engineering, with a proven track record of designing, building, and scaling distributed, cloud-native systems in production.
    • Demonstrated experience as a technical leader or architect, accountable for the key decisions on system design, scalability, performance, and cost optimization.
    • Experience designing security into a multi-tenant platform, including authorization boundaries between tenants and handling of sensitive data such as PII and PHI, with awareness of LLM-specific risks like prompt injection and tool abuse.
    • Extensive experience building and maintaining AI/ML infrastructure in production, including model deployment and lifecycle management, delivered as a multi-tenant product with external users rather than internal tooling for a single team. Candidates whose experience is limited to building pipelines for their own team will not be a fit.
    • Deep, hands-on experience taking LLM-based systems to production, including RAG architecture, retrieval and embedding design, prompt and model versioning, and tool or function calling. Not just prototyping with an SDK. We are looking for someone who has operated these systems under real traffic, real latency budgets, and real failure modes.
    • Expert-level coding skills in TypeScript and Python building robust APIs and backend services, with the judgment to critically evaluate AI-generated code for correctness, security, and architectural fit.
    • Production-level experience with a model registry and serving stack, ideally Databricks MLflow, including model registration, versioning, asset bundles, and serving workflows.
    • Experience treating AI evaluation as a release gate rather than post-hoc reporting, including eval harnesses, regression gates, and drift or quality monitoring for non-deterministic systems.
    • Proficiency in API-first design, including REST and OpenAPI specifications, designing APIs that are scalable, secure, versioned, and extensible.
    • Solid working knowledge of AWS and containerized workloads (e.g., Docker), and familiarity with infrastructure-as-code such as CloudFormation or CDK, with the ability to contribute to CI/CD pipelines and deployment automation.
    • Experience defining observability and SLI/SLO/SLA practice for production systems, including monitoring, alerting, and distributed tracing.
    • Ability to articulate ideas clearly to customers and cross-functional teams, influence technical direction on teams you do not manage, and mentor other engineers.

Nice to Have

    • Familiarity with emerging LLM frameworks for advanced prompt orchestration and programmatic LLM pipelines.
    • Experience running agentic or multi-step orchestration in production, and with MCP as an integration surface for tooling and non-human identities.
    • Understanding of LLM cost monitoring, latency optimization, and usage analytics in production environments, including per-tenant cost attribution for tokens, GPU, and inference.
    • Experience with multimodal model inputs, including image and instrument data, and the throughput and cost implications of serving them at scale.
    • Experience with fine-tuning, distillation, or model optimization such as quantization, batching, or KV-cache strategy, to improve latency and cost.
    • Experience delivering ML or AI systems in a regulated or validated environment (GxP, 21 CFR Part 11, SOC 2), including computer system validation and audit readiness.
    • Background in scientific, life sciences, or laboratory data domains.

Benefits

  • 100% employer-paid benefits for all eligible employees and immediate family members
  • Unlimited paid time off (PTO)
  • 401K
  • Flexible working arrangements - Remote work
  • Company paid Life Insurance, LTD/STD
  • A culture of continuous improvement where you can grow your career and get coaching
  • The salary range for this position is $200K-$270K USD. The salary range posted reflects our target baseline for this role. Final compensation is determined by a thorough evaluation of factors including the candidate’s specific experience, localized market data, and internal team equity.

We are not currently providing visa sponsorship for this position.

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Pay
A culture of continuous improvement where you can grow your career and get coaching The salary range for this position is $200K-$270K USD. The salary range posted reflects our target baseline for this role. Final compensation is determined by a thorough evaluation of factors including the candidate’s specific experience, localized market data, and internal team equity. We are not currently providing visa sponsorship for this position.
Location & working pattern

Cambridge, Massachusetts, United States

- 401K - Flexible working arrangements - Remote work - Company paid Life Insurance, LTD/STD
Work authorization
- The salary range for this position is $200K-$270K USD. The salary range posted reflects our target baseline for this role. Final compensation is determined by a thorough evaluation of factors including the candidate’s specific experience, localized market data, and internal team equity. We are not currently providing visa sponsorship for this position.

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