Pay
Higher than most similar jobs
$252K–$336K against $166K–$240K, the middle half of what similar US postings state.
From 1,279 postings in the last year. Stated ranges, not salaries paid.
Cambridge, MA USA; San Francisco, CA USA
Live, first seen by us 29 days agoExpected Base Salary Range $252,000—$336,000 USD About LILARead the full posting
Lead post-training of models with SFT and RL methods (DPO, PPO/GRPO)
Build and run evaluation loops measuring model quality, reliability, and customer fit
Turn customer learnings and evaluation results into model improvement cycles
Debug complex model failures using traces, evaluations, and customer context
Integrate model behavior into end-to-end product workflows with Software
Lead post-training efforts using approaches such as SFT and RL (DPO, PPO/GRPO)
Build and run evaluation loops that measure model quality, reliability, and customer fit
Turn customer learnings, data signals, and evaluation results into concrete model improvement cycles
Debug complex model failures using traces, evaluations, customer context, and scientific feedback
Work with Software to integrate model behavior into end-to-end product workflows
Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges.
In the employer’s words · Read in context
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Higher than most similar jobs
$252K–$336K against $166K–$240K, the middle half of what similar US postings state.
From 1,279 postings in the last year. Stated ranges, not salaries paid.
Day 29
Similar jobs usually come down between day 6 and day 70.
At Lila Sciences, jobs usually come down by about day 63.
From 4,481 similar postings that came down, and 12 of Lila Sciences’s. Coming down is not always a hire.
16 open jobs
Open jobs by the week we first saw them, last 12 weeks.
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- Minimum 2-3 years of hands-on post-training experience (SFT, RL methods such as DPO/PPO/GRPO) and evaluation system design, gained from having solved these problems many times before. - Strong software engineering skills in Python and modern ML frameworks like PyTorch. - A demonstrated ability to debug ambiguous, high-stakes model behavior quickly, using data, traces, logs, and qualitative feedback - the kind of judgment that only comes from having seen many failure modes before.
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New ML Engineer postings at the employers we follow are up 12% over the last 5 weeks compared with the 5 before.
Each bar is one week of new postings. The darkest bars are the last 5 weeks.
Counted from the hiring pages we’ve followed for at least five weeks, so employers we add don’t look like growth. Updated weekly.
We file this job under ML Engineer, by the work the posting describes.
ML engineers put machine learning models into products. They write the code that trains, ships, serves and monitors models so a recommendation or prediction works for real users.
Postings ask for strong Python and software engineering, a framework such as PyTorch, cloud services, and more and more often experience with large language models.
A data scientist often works out which model to build; an ML engineer makes it run reliably in production.
The government has no code for ML engineers, so these figures are for the closest group, computer and information research scientists.
Source: US Bureau of Labor Statistics, Occupational Employment and Wage Statistics (May 2025) and Employment Projections (2025 to 2035). Occupation code 15-1221.
Your Impact at LILA
We are growing our Applied AI org and seeking a Principal Machine Learning Engineer, Applied AI with deep expertise in model post-training, evaluation, and production-oriented ML systems. You’ll shape how Lila’s AI models are adapted to customer-specific scientific needs, with a focus on turning frontier model capabilities into reliable workflows that can be evaluated, iterated and used in real customer contexts.
Applied AI sits at the intersection of AI Research, model engineering, and product deployment. The team partners closely with AI Researchers and Software teams to adapt Lila models to customer workflows, improve model quality through post training and driving how harness engineering shapes model behavior inside the product.
This is a high-impact senior IC role for someone who brings deep, hands-on expertise in model post-training, evaluation, and production ML systems, built over many years of solving this exact class of problem.
What You'll Be Building
What You'll Need to Succeed
Bonus Points For
Compensation
We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.
U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.
International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.
About LILA
Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.
LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai.
Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.
We’re All In
Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.
A Note to Agencies
Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.
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Expected Base Salary Range $252,000—$336,000 USD About LILA
Cambridge, MA USA; San Francisco, CA USA
Working pattern and location restrictions need checking in the full posting.
We’re All In Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.