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Senior Manager, Technical Clinical Data Management

Pay
$164,000–200,000/year · BaseAnnual period assumed — pay source
Additional Information Deciphera is committed to fair and equitable compensation practices. The base salary pay range for this role is $164,000 - $200,000. Actual compensation packages will depend on various factors, including, but not limited to depth of experience, education, skillset, overall performance and/or location. Deciphera believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Deciphera’s competitive total rewards strategy that also includes annual performance bonus, a long-term incentive plan, full range of benefits and other incentive compensation plans (if applicable)
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Work setting
Remote — work setting source
Work setup in the employer’s posting: Remote
From the employer’s posting
Employment
Full-time — employment source
Employment type in the employer’s posting: Full-time
From the employer’s posting

What you’ll work on

Full posting
  • Lead study communications and manage expectations with the Data Management CRO

  • Oversee all Data Management Plan activities and study deliverables

  • Oversee outsourced CDM vendors and review their invoices

  • Partner with IT on external data transfers and cross-system data integration

  • Lead CDM inspection activities and resolve findings

From the employer’s posting
lead study communications, and manage expectations with the Data Management CRO
Oversee all activities defined in the Data Management Plan (DMP)
Oversee outsourced CDM vendors and ensure performance aligns with Deciphera standards
Partner with IT to streamline external data transfers and integrate data across systems
Lead CDM inspection activities and manage findings to resolution

What you’ll bring

All qualifications

Core experience

  • Bachelor's or master's degree with 8+ years of experience in Clinical Data Management
  • Experience building in Medidata RAVE
  • Knowledge of FDA/CFR and ICH/GCP
  • Hands on experience using SAS for data extraction and validation
  • Familiarity of CDISC and CDASH standards
  • Experience with data visualization tools to build study-status and data quality dashboards
Qualification wording
Bachelor's or master's degree with 8+ years of experience in Clinical Data Management
Experience building in Medidata RAVE
Knowledge of FDA/CFR and ICH/GCP
Hands on experience using SAS for data extraction and validation
Familiarity of CDISC and CDASH standards
Experience with data visualization tools to build study-status and data quality dashboards
Education & alternatives
Qualifications - Bachelor's or master's degree with 8+ years of experience in Clinical Data Management - Knowledge of FDA/CFR and ICH/GCP

Benefits in the posting

Full benefits wording
  • Competitive salary and annual bonus.
  • Comprehensive benefits package including medical, dental, vision insurance, 401(k) retirement plan with company match, and more.
  • Generous parental leave and family planning benefits.
  • EQUAL EMPLOYMENT OPPORTUNITY INFORMATION
  • Company Description

From the employer’s posting.

Posting record

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Actively hiringFirst seen by us 5 days ago, still listed, and not a repost of an earlier posting.

Status in our records
Live
First seen by us
Oct 30, 20265 days ago
Recorded sightings
5
Last seen by us
Nov 3, 2026

These dates show when we found the posting. Check the employer’s website to confirm it is still accepting applications.

How this job compares

Pay

In line with similar jobs

$164K–$200K against $154K–$225K, the middle half of what similar US postings state.

From 2,958 postings in the last year. Stated ranges, not salaries paid.

Time since we first saw it

Day 5

Early. Similar jobs usually come down between day 7 and day 53.

From 7,804 similar postings that came down. Coming down is not always a hire.

Deciphera Pharmaceuticals is hiring

4 open jobs

Open jobs by the week we first saw them, last 12 weeks.

  • Hiring is picking up
Hiring record

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  • SAS
Where the posting names them
- Experience building in Medidata RAVE - Hands on experience using SAS for data extraction and validation - Experience with J-Review

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About the role

We file this job under Data Leadership, by the work the posting describes.

Data leaders run data teams or design how a company's data fits together. Managers hire, set priorities and answer for whether the data work pays off; architects choose the systems and the shape of the data.

Expect years of hands-on data work, experience leading people or projects, and the ability to explain tradeoffs to executives.

Unlike a senior engineer or analyst, most of a data leader's week goes to people, planning and decisions rather than building.

US government figures for computer and information systems managers

Median yearly pay, May 2025
$175,140
Expected change, 2025 to 2035
15.8% more jobsagainst 3.5% for all jobs

The government has no code for data leaders, so these figures are for the closest group, computer and information systems managers, which includes data processing and data operations managers.

Source: US Bureau of Labor Statistics, Occupational Employment and Wage Statistics (May 2025) and Employment Projections (2025 to 2035). Occupation code 11-3021.

Job description

View original posting ↗

Job Description

We are seeking an experienced Senior Manager, Technical Clinical Data Management to take full accountability for end-to-end data management lifecycle activities across assigned clinical trials. In this dual-function role, the individual will serve as the primary Data Management Study Lead, managing timelines, cross-functional communication, risks, and deliverables while also applying hands-on technical expertise.  Candidate will combine strong clinical data management leadership with the technical ability to design efficient, scalable solutions that improve data quality, accelerate issue resolution, and support timely study delivery.

Key Responsibilities:
Clinical Data Management Leadership & Technical Operations 

Leadership & Study Oversight

  • Represent Data Management on the Clinical Study Team, lead study communications, and manage expectations with the Data Management CRO
  • Oversee all activities defined in the Data Management Plan (DMP) and ensure study deliverables meet quality and timeline expectations

Technical Operations

  • Advance vendor oversight by applying data intelligence to identify trends, strengthen performance monitoring, and improve operational efficiency
  • Partner with IT to streamline external data transfers and integrate data across systems for cross-functional use

Vendor & Stakeholder Management 

  • Oversee outsourced CDM vendors and ensure performance aligns with Deciphera standards
  • Review vendor invoices as applicable
  • Collaborate with cross functional team on data deliverables

Leadership, Process & Continuous Improvement 

  • Enhance CDM processes and strengthen cross functional collaboration
  • Support department initiatives as needed

Inspection Readiness, Quality & Metrics 

  • Lead CDM inspection activities and manage findings to resolution
  • Ensure CDM documentation is complete and filed in the TMF

Other duties and responsibilities as assigned

Qualifications

  • Bachelor's or master's degree with 8+ years of experience in Clinical Data Management
  • Knowledge of FDA/CFR and ICH/GCP
  • Familiarity of CDISC and CDASH standards
  • Experience with data visualization tools to build study-status and data quality dashboards
  • Experience creating and applying tools to clinical data workflows, including data review, automation, and visualization with appropriate validation and human oversight
  • Familiarity with AI (e.g. Copilot, Claude)
  • Effective communication, organizational, and project management skills

Preferred Capabilities:

  •  Experience building in Medidata RAVE
  •  Hands on experience using SAS for data extraction and validation
  •  Experience with J-Review

Additional Information

Deciphera is committed to fair and equitable compensation practices. The base salary pay range for this role is $164,000 - $200,000. Actual compensation packages will depend on various factors, including, but not limited to depth of experience, education, skillset, overall performance and/or location.

Deciphera believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Deciphera’s competitive total rewards strategy that also includes annual performance bonus, a long-term incentive plan, full range of benefits and other incentive compensation plans (if applicable)

Benefits:

  • Competitive salary and annual bonus.
  • Comprehensive benefits package including medical, dental, vision insurance, 401(k) retirement plan with company match, and more.
  • Generous parental leave and family planning benefits.
  • Outstanding culture and opportunities for personal and professional growth.

EQUAL EMPLOYMENT OPPORTUNITY INFORMATION

Deciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements, we invite you complete the confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process, and has no effect on your opportunity for employment. This information will also be treated confidentially.  We are committed to make all hiring decisions and other employment decisions on a non-discriminatory basis.

Company Description

Deciphera, a member of Ono Pharmaceutical Co., Ltd., is a biopharmaceutical company focused on discovering, developing, and commercializing important new medicines and providing hope to people living with cancer, neurologic and autoimmune disease. The spirit of collaboration that has brought medications to life continues to guide how we operate, grow, and discover new breakthroughs. We cultivate an inclusive culture that values curiosity, creativity, and shared accountability—empowering individuals to challenge the unknown together. Learn more about Deciphera, a member of Ono Pharmaceutical Co., Ltd., by visiting our website: https://deciphera.com

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Pay
Additional Information Deciphera is committed to fair and equitable compensation practices. The base salary pay range for this role is $164,000 - $200,000. Actual compensation packages will depend on various factors, including, but not limited to depth of experience, education, skillset, overall performance and/or location. Deciphera believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Deciphera’s competitive total rewards strategy that also includes annual performance bonus, a long-term incentive plan, full range of benefits and other incentive compensation plans (if applicable)
Location & working pattern

Waltham, MA, United States

Working pattern and location restrictions need checking in the full posting.

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