&lt;p&gt;&lt;strong&gt;Senior Scientist/ Principal Scientist, Capsid Biologics&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;&amp;nbsp;&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Company Summary&lt;/strong&gt;&lt;strong&gt;&lt;br&gt;&lt;/strong&gt;Ring Therapeutics Inc. is a privately held, early-stage biotechnology company pioneering a novel form of gene therapy by exploiting a family of naturally occurring commensal viruses to create the first re-dosable and targetable viral vector. This approach enables a powerful new class of tropic, persistent, non-integrating vectors that overcome the immunogenicity, and limited tropism of existing gene therapy vectors. Ring Therapeutics is leveraging this versatile technology to develop a broad pipeline of novel, targeted medicines for disease with high unmet medical need.&lt;br&gt;&lt;br&gt;Ring Therapeutics was founded by Flagship Pioneering, focused on launching breakthrough companies based on internally conceived innovations and insights. Flagship Pioneering has created over 40 groundbreaking companies over the past fifteen years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Seres Therapeutics (MCRB), Syros Pharmaceuticals (SYRS), Axcella Health, Evelo Biosciences (EVLO), and Indigo Agriculture.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;&amp;nbsp;&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Job Description&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;About this Role&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;The Platform Assembly and Delivery group at Ring Therapeutics is seeking an experienced and highly motivated protein engineer and protein biochemist to contribute to the discovery and development of gene delivery technology for Anellovirus platform. In this role, you will work in a fast-paced, highly dynamic, and innovative environment supporting cross-functional collaborations to streamline novel capsid discovery workflow machinery and chart protein payload discovery roadmap.&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;The successful candidate will develop and deploy high-throughput affinity purification, generation and characterization for novel capsid protein and monoclonal antibody that support advancing ANV (Anellovirus) viral particle pipeline and therapeutic programs. The scientific leader at this position will partner across broad functional teams with Genomics, Synthetic Biology, Protein Science, In Vitro Biology, and Translational to drive capsid protein and VLP purification and characterization, protein payload generation and design, and reagent tool generations advancing novel ANV (Anellovirus) viral particles in vitro and in vivo for viral delivery. The Senior Scientist/ Principal Scientist at this role is expected to execute and lead junior researchers in the lab performing ranges of biochemical and biophysical assays for assessing capsid protein function and antibody performance.&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;What You’ll Do&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Develop and implement high-throughput affinity purification workstream advancing capsid protein discovery and VLP characterization&lt;/li&gt;
&lt;li&gt;Design and execute antibody discovery campaign leveraging animal immunization approaches and/ or display technologies&lt;/li&gt;
&lt;li&gt;Perform biochemical analyses and biophysical characterization of capsid proteins, VLPs, antibodies, antibody fragments, and related proteins via SDS-PAGE, HPLC, ÄKTA, Mass Photometer, ELISA, size-exclusion chromatography (SEC), and bio-layer interferometry (BLI, Octet)&lt;/li&gt;
&lt;li&gt;Generate, analyze, and present the capsid protein and antibody biophysical and biochemical characterization data that will be used to select and advance lead molecules (protein property and propensity, stability, antibody binding affinity, antibody epitope binning/mapping, functional assays)&lt;/li&gt;
&lt;li&gt;Implement methods for efficient, high-throughput screening and selection of therapeutic capsids and protein payloads using various modalities of IgG, VHH, and ScFv&lt;/li&gt;
&lt;li&gt;Support various projects with diverse antibody engineering needs including affinity maturation, ScFv conversion, humanization, and stabilization.&lt;/li&gt;
&lt;li&gt;Be responsible for the operation and maintenance of AKTA, Octet and analytical SEC-HPLC instruments&lt;/li&gt;
&lt;li&gt;Collaborate with internal and external teams to ensure timely progress in research projects&lt;/li&gt;
&lt;li&gt;Interpret results, identify problems, and develop troubleshooting plans&lt;/li&gt;
&lt;li&gt;Perform other duties and responsibilities, as assigned&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Qualifications&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Who you are&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;You are a wet-bench protein engineering scientific leader who is passionate about innovations and tackling key challenges in therapeutic platform discovery and development through technology innovation. You enjoy working as part of an innovative, collaborative, and dynamic team, and have strong communication and interpersonal skills.&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Required skills&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;D. degree or MS degree in relevant fields with experience working in a combination of protein engineering, protein biochemistry, antibody discovery and engineering, and characterization in biotech/pharma settings&lt;/li&gt;
&lt;li&gt;Minimum 5-8 years of post-degree experience in industry or academia for Ph.D. degree candidates; minimum 8-12 years of industry experience for MS degree candidates.&lt;/li&gt;
&lt;li&gt;In-depth industrial experience in the field of current state-of-the-art protein engineering skillsets with therapeutic antibody experience is a plus using platforms such as high-throughput purification, In Silico design, functional hybridoma, single b-cell technologies, phage or yeast display (including FACS analysis and sorting), as well as expert-level general molecular biology skills, applied towards library design, construction, affinity-maturation, humanization and other engineering aspects&lt;/li&gt;
&lt;li&gt;Experience with VHH and/ or ScFv antibody modalities and cell therapy is an excellent advantage&lt;/li&gt;
&lt;li&gt;Experience with standard molecular and cell biology techniques&lt;/li&gt;
&lt;li&gt;Ability to develops and oversees novel scientific projects and will manage the work of others directly or in a matrixed structure&lt;/li&gt;
&lt;li&gt;Ability to independently manages workload and expectations, provides information to group to influence direction&lt;/li&gt;
&lt;li&gt;Effective resource and time management is essential&lt;/li&gt;
&lt;li&gt;Effective oral and written communication as well as strong interpersonal skills required&lt;/li&gt;
&lt;li&gt;Can-do attitude, enthusiastic, self-motivated, team oriented with a strong collaborative spirit&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;

Senior Scientist/ Principal Scientist, Capsid Biologics

&lt;div class=&quot;content-intro&quot;&gt;&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;Who we are&lt;br&gt;&lt;/strong&gt;&lt;/span&gt;&lt;span class=&quot;normaltextrun&quot; style=&quot;font-size: 12pt;&quot;&gt;&lt;span style=&quot;color: black;&quot;&gt;At CarGurus (NASDAQ: CARG), our mission is to give people the power to reach their destination. We started as a small team of developers determined to bring trust and transparency to car shopping. Since then, our history of innovation and go-to-market acceleration has driven industry-leading growth. In fact, we’re the largest and fastest-growing automotive marketplace, and we’ve been profitable for over 15 years.&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;What we do&lt;/strong&gt;&lt;br&gt;The market is evolving, and we are too, moving the entire automotive journey online and guiding our customers through every step. That includes everything from the sale of an old car to the financing, purchase, and delivery of a new one. Today, tens of millions of consumers visit CarGurus.com each month, and ~30,000 dealerships use our products. But they&#x27;re not the only ones who love CarGurus—our employees do, too. We have a people-first culture that fosters&amp;nbsp;kindness, collaboration, and innovation, and empowers our Gurus with tools to fuel their career growth. Disrupting a trillion-dollar industry requires fresh and diverse perspectives. Come join us for the ride!&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;p&gt;&lt;strong&gt;Product Data Analytics Managers &lt;/strong&gt;manage a team of highly skilled product data analyst that support our Product and Engineering teams, providing the final word on all analytics for CarGurus’ user and dealer experiences. The ideal candidate has a curiosity about seeing solutions in sprawling data sets and the business approach to convert insights into strategic opportunities for our company. You’ll work closely with leaders across engineering, product, data engineering, data science, marketing, and other go-to-market teams to support and implement high-quality, data-driven decisions. In doing so, you will gain exposure to multiple dimensions of the business and cross-functionally influence many different roadmaps in addition to your own.&lt;/p&gt;
&lt;h2&gt;&lt;strong&gt;What You’ll Take on:&lt;/strong&gt;&lt;/h2&gt;
&lt;ul&gt;
&lt;li&gt;&lt;strong&gt;Exploration&lt;/strong&gt;: Using your SQL/Python expertise, lead a team of analysts to conduct exploratory empirical analyses that bridge disparate data sources (e.g. clickstream data, subscription records, inventory volumes, etc.) to quantify product performance, user behavior, and/or market trends. Relentlessly dig into the data and collaborating with other individuals and teams.&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Process&lt;/strong&gt;: Design and build technical processes to address business issues. Supervise the data/report requests process: tracking requests submitted, prioritization, approval, etc. Optimize processes for data intake, validation, mining and engineering as well as modeling, visualization and communicate outcomes.&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Metrics&lt;/strong&gt;: Be responsible for the design and delivery of reports and insights that analyze business functions and key operations and performance metrics. Craft the metrics that define business success, condensing abstract or loosely-defined concepts down to concrete calculations. Audit and improve existing metrics to better advise the business’ needs.&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Advocacy&lt;/strong&gt;: Advocate for specific, data-driven product innovations that help further high-level company strategy, primarily in partnership with the Product/Engineering teams. Participate in brainstorming and planning discussions across the organization to these ends. Avoid passivity in the face of flawed proposals; thoughtfully and persuasively push back against potential missteps.&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Experimentation&lt;/strong&gt;: Be a source of guidance for A/B experimentation, advising engineers, product managers, and high-level team members on the necessary data points to collect, required sample sizes, optimal metrics to examine, robustness of numerical findings, and the bottom-line success or failure of the tested changes. Suggest improvements to A/B testing-related tools, algorithms, and automated processes.&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Visualizations&lt;/strong&gt;: Build intuitive dashboards and other visual monitoring tools to guide daily decision-making by senior partners and the company at large. Experiment with new kinds of visualizations that you believe could be better applied in the organization. Re-work underlying code to appropriately structure visualization inputs.&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Architecture&lt;/strong&gt;: Conceive of new data assets and build automated transformations (via DBT, LookML, etc.) to bring them to fruition. Partner with Data Engineering teams to advance core data modeling/architecture (e.g. user clickstream logs), by optimizing, integrating, and distilling large raw datasets and metadata. Draw upon prior experience with expansive, unrefined datasets to fix modeling bottlenecks in quick, scalable, outside-of-the-box ways.&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Communication&lt;/strong&gt;: Communicate and present complex quantitative findings in easily digestible terms to company leadership, homing in on key takeaways. Concretely and informatively respond to any probing, on-the-spot follow-up questions from senior decision-makers.&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Training&lt;/strong&gt;: Train, develop and supervise analyst-level employees. When required, be comfortable creating onboarding plans and training materials. Be proficient within our tech stack so that you can guide analysts towards innovative data solutions.&lt;/li&gt;
&lt;/ul&gt;
&lt;h2&gt;&lt;strong&gt;Who You Are:&lt;/strong&gt;&lt;/h2&gt;
&lt;ul&gt;
&lt;li&gt;&amp;nbsp;5+ years of demonstrated ability in an analytics or analytics-adjacent field, ideally involving sophisticated data modeling, quantitative analysis, and applied statistics.&lt;/li&gt;
&lt;li&gt;2+ years experience managing a team.&lt;/li&gt;
&lt;li&gt;A natural thought leader with a consistent record of influencing business strategy through proven team member management skills.&lt;/li&gt;
&lt;li&gt;Expertise using SQL. Strong background in Python is highly desirable.&lt;/li&gt;
&lt;li&gt;Solid understanding of data mining principles: predictive analytics, mapping, user-tracking, collecting data from multiple data systems on premises and cloud-based data sources.&lt;/li&gt;
&lt;li&gt;Understanding of and experience using analytical concepts and statistical techniques: hypothesis development, designing tests/experiments, analyzing data, drawing conclusions, and developing practical recommendations for business units.&lt;/li&gt;
&lt;li&gt;Second-nature understanding of core statistical concepts (regression, significance testing, omitted variable bias, independence/dependence, etc.)&lt;/li&gt;
&lt;li&gt;Interest in creative data visualizations.&lt;/li&gt;
&lt;li&gt;Willingness to step outside your role and independently come up with novel ideas for the business.&lt;/li&gt;
&lt;li&gt;Able to challenge others’ ideas and advocate for your own.&lt;/li&gt;
&lt;li&gt;Excellent verbal and written communication skills. Very comfortable communicating high-impact and potentially critical findings to senior leadership.&lt;/li&gt;
&lt;li&gt;Strong project planning skills, with experience building roadmaps, estimating required resources, and flagging inter-dependencies with other teams/projects.&lt;/li&gt;
&lt;li&gt;Strong ability to plan and prioritize numerous processes, people and projects simultaneously.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;The exceptional candidate will also be proficient and experienced with the following tools/programs:&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Looker&lt;/li&gt;
&lt;li&gt;Snowflake&lt;/li&gt;
&lt;li&gt;DBT&lt;/li&gt;
&lt;li&gt;Salesforce&lt;/li&gt;
&lt;li&gt;Jira&lt;/li&gt;
&lt;li&gt;Snowplow&lt;/li&gt;
&lt;li&gt;Google Suite&lt;/li&gt;
&lt;li&gt;Microsoft Suite&lt;/li&gt;
&lt;/ul&gt;&lt;div class=&quot;content-conclusion&quot;&gt;&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;Working at CarGurus&lt;/strong&gt; &lt;br&gt;We reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;We welcome all&lt;/strong&gt;&lt;br&gt;CarGurus strives to be a place to which people can bring the ultimate expression of themselves and their potential—starting with our hiring process. We do not discriminate based on race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation. We foster an inclusive environment that values people for their skills, experiences, and unique perspectives. That’s why we hope you’ll apply even if you don’t check every box listed in the job description. We want to know what only &lt;em&gt;you &lt;/em&gt;can bring to CarGurus.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot; data-lucid-type=&quot;application/vnd.lucid.text&quot; data-lucid-content=&quot;{&amp;quot;t&amp;quot;:&amp;quot;Working at CarGurus \nWe reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&amp;quot;,&amp;quot;m&amp;quot;:[{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;b&amp;quot;,&amp;quot;v&amp;quot;:true,&amp;quot;e&amp;quot;:19},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#000000ff&amp;quot;,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:19.999999999999996,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:19,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#1d1c1dff&amp;quot;,&amp;quot;e&amp;quot;:730},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:20,&amp;quot;e&amp;quot;:730}]}&quot;&gt;&lt;strong&gt;Additional information&lt;/strong&gt; &lt;br&gt;&lt;/span&gt;&lt;span data-lucid-type=&quot;application/vnd.lucid.text&quot; data-lucid-content=&quot;{&amp;quot;t&amp;quot;:&amp;quot;Working at CarGurus \nWe reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&amp;quot;,&amp;quot;m&amp;quot;:[{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;b&amp;quot;,&amp;quot;v&amp;quot;:true,&amp;quot;e&amp;quot;:19},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#000000ff&amp;quot;,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:19.999999999999996,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:19,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#1d1c1dff&amp;quot;,&amp;quot;e&amp;quot;:730},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:20,&amp;quot;e&amp;quot;:730}]}&quot;&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;US employees must provide proof of full vaccination against COVID-19 unless they have an approved medical or religious accommodation. &lt;/span&gt;&lt;span style=&quot;color: #ffffff;&quot;&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;#LI-H&lt;/span&gt;ybrid&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;

Manager, Product Data Analytics

&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;7migg&quot; data-offset-key=&quot;7ntq6-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;7ntq6-0-0&quot;&gt;
&lt;p&gt;&lt;strong&gt;Company Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Tessera Therapeutics is pioneering Gene Writing™— a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy. Tessera Therapeutics was founded by Flagship Pioneering, a life sciences innovation enterprise that conceives, resources, and develops first-in-category companies to transform human health and sustainability.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;We are seeking an enthusiastic, innovative, and collaborative individual to characterize the RNA Rewriting mechanism for advancement of the platform. The Scientist will also be involved in the design and testing of novel gene writers using a variety of molecular and cellular techniques. The successful candidate will leverage their knowledge of DNA repair proteins/pathways and keep up with DNA repair literature to inform innovative implementations to our technology. This individual will join a dynamic, rapidly growing, and highly collaborative team that is employing diverse expertise to further the development of the RNA Rewriting platform.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Work both independently and as part of a collaborative team to develop assays for characterization of the RNA Rewriting mechanism.&lt;/li&gt;
&lt;li&gt;Plan, execute/record, and troubleshoot experiments to characterize novel gene writer candidates.&lt;/li&gt;
&lt;li&gt;Interface with cross-functional groups with specialized expertise for downstream sample processing.&lt;/li&gt;
&lt;li&gt;Independently analyze data and present results to the larger scientific team.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Basic Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;PhD with experience in molecular biology, cell biology, genetics or related fields.&lt;/li&gt;
&lt;li&gt;Deep understanding of mammalian DNA repair pathways.&lt;/li&gt;
&lt;li&gt;Experience with DNA pull-down followed by proteomics and/or genome-wide perturbation tools from mammalian cell culture.&lt;/li&gt;
&lt;li&gt;Extensive experience in mammalian cell culture experimentation techniques, including transfection, and protein and genomic DNA extraction.&lt;/li&gt;
&lt;li&gt;Experience in a range of molecular and cell biology techniques.&lt;/li&gt;
&lt;li&gt;Ability to thrive in a cross-functional, multi-disciplinary environment and in an agile and highly collaborative fashion.&lt;/li&gt;
&lt;li&gt;Strong attention to detail in experimental execution and record-keeping.&lt;/li&gt;
&lt;li&gt;Excellent communication and presentation skills, capable of conveying technical information to diverse audiences.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Preferred Experience (not required):&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Experience with DNA structural analysis techniques&lt;/li&gt;
&lt;li&gt;Demonstrated experience with chromatin proteomics and/or genome-wide genetic perturbations tools&lt;/li&gt;
&lt;li&gt;Experience with genome engineering systems&lt;/li&gt;
&lt;li&gt;Experience with NGS library preparation&lt;/li&gt;
&lt;li&gt;Experience with protein engineering&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;More About Flagship Pioneering&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Flagship Pioneering conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, the firm has, through its Flagship Labs unit, applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $50B in aggregate value. To date, Flagship has deployed over $2.2B in capital toward the founding and growth of its pioneering companies alongside more than $18B of follow-on investments from other institutions. The current Flagship ecosystem comprises 41 transformative companies, including Axcella Health (NASDAQ: AXLA), Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO), Foghorn Therapeutics (NASDAQ: FHTX), Indigo Ag, Kaleido Biosciences (NASDAQ: KLDO), Moderna (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology, Seres Therapeutics (NASDAQ: MCRB), and Sigilon Therapeutics (NASDAQ: SGTX).&lt;/p&gt;
&lt;p&gt;Flagship Pioneering and our ecosystem companies are&amp;nbsp;&lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt;&amp;nbsp;regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;&lt;em&gt;Recruitment &amp;amp; Staffing Agencies:&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;&amp;nbsp; Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates.&amp;nbsp; The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team.&amp;nbsp;&amp;nbsp; Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/p&gt;
&lt;/div&gt;
&lt;/div&gt;

Senior Research Associate, Molecular and Cellular Biology

&lt;div class=&quot;content-intro&quot;&gt;&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;Who we are&lt;br&gt;&lt;/strong&gt;&lt;/span&gt;&lt;span class=&quot;normaltextrun&quot; style=&quot;font-size: 12pt;&quot;&gt;&lt;span style=&quot;color: black;&quot;&gt;At CarGurus (NASDAQ: CARG), our mission is to give people the power to reach their destination. We started as a small team of developers determined to bring trust and transparency to car shopping. Since then, our history of innovation and go-to-market acceleration has driven industry-leading growth. In fact, we’re the largest and fastest-growing automotive marketplace, and we’ve been profitable for over 15 years.&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;What we do&lt;/strong&gt;&lt;br&gt;The market is evolving, and we are too, moving the entire automotive journey online and guiding our customers through every step. That includes everything from the sale of an old car to the financing, purchase, and delivery of a new one. Today, tens of millions of consumers visit CarGurus.com each month, and ~30,000 dealerships use our products. But they&#x27;re not the only ones who love CarGurus—our employees do, too. We have a people-first culture that fosters&amp;nbsp;kindness, collaboration, and innovation, and empowers our Gurus with tools to fuel their career growth. Disrupting a trillion-dollar industry requires fresh and diverse perspectives. Come join us for the ride!&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;Role overview&lt;/strong&gt;&lt;/span&gt;&lt;br&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;CarGurus uses data to support, enhance, and enrich our people and projects as well as our product development. Our Data Engineering department is actively looking for a &lt;strong&gt;Manager of Data Platform&lt;/strong&gt; to play a multi-functional management role, with the responsibility of defining and implementing a Data Platform Strategy. In addition to directly managing our Data Platform organization, this leader will work with Product Engineering, Analytics Engineering, and InfoSec with a goal of improving data ingestion and data platform evolution. This individual will influence other data teams to define, socialize, gain consensus, and drive execution on a plan to establish a scalable Data Engineering Platform Strategy.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;What you’ll do&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Gain a deep understanding of our evolving data and analytics stack&amp;nbsp;&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Define and drive tactical decisions around Data Platform domain while providing input into larger strategic decisions around data infrastructure&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Grow, nurture, and evolve the Data Platform Engineering function to build a best-in-industry team&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Partner with Data Science, Analytics Engineering and Product Engineering teams to acquire and maintain an understanding of current and future business context and requirements&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Partner with infrastructure teams to develop next generation data platform capabilities&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Work with ours partners and stakeholders to build and maintain a technical roadmap that solves our biggest data challenges&amp;nbsp;&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Build an data platform strategy and ensure the Data Engineering department can support the growing needs of the business&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Ingest and maintain pipelines to help maintain a single view of the common data required by different teams and subject areas to perform their responsibilities by creating and maintaining high quality data products&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Codify and evolve data platform standards that define how activity in proprietary and third-party platforms should be set up and ensure data can be captured and collected to satisfy data requirements and needs&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Work on promoting cross-disciplined roles &amp;amp; responsibilities and processes to set and promote data standards&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Deliver ongoing data quality validation as part of data pipelines and take proactive measures to improve data quality&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Help maintain a central data dictionary to help our end users navigate the CarGurus data universe&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Provide insights to data engineering leadership on how to improve data quality across the enterprise, and facilitate conversations with key data and engineering leaderships across the organization to help them overcome systemic problems&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Work closely with the Data Architecture Guild to identify and solve systemic data issues, and formulate plans to address architectural needs&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;What you&#x27;ll bring&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;5+ years of experience as a data engineer, software engineer, or related field &amp;nbsp;&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;3+ years of people management experience&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Professional experience developing and executing on a data warehouse and/or data platform strategy using a modern data stack – at CarGurus, we use Snowflake, DBT, airflow, and docker &amp;nbsp;&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Ability to move quickly in a dynamic and cross-functional team environment &amp;nbsp;&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Expertise in SQL, Python, and system architecture – with the ability to understand the context of a business need and build a system that addresses it&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Proven track record of rolling out and establishing scalable data and analytics platforms (we use Snowflake, dbt and Looker) with terabyte size data sets&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Comfortable leading technical team discussions regarding architecture and problem solving&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;&lt;div class=&quot;content-conclusion&quot;&gt;&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;Working at CarGurus&lt;/strong&gt; &lt;br&gt;We reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;We welcome all&lt;/strong&gt;&lt;br&gt;CarGurus strives to be a place to which people can bring the ultimate expression of themselves and their potential—starting with our hiring process. We do not discriminate based on race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation. We foster an inclusive environment that values people for their skills, experiences, and unique perspectives. That’s why we hope you’ll apply even if you don’t check every box listed in the job description. We want to know what only &lt;em&gt;you &lt;/em&gt;can bring to CarGurus.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot; data-lucid-type=&quot;application/vnd.lucid.text&quot; data-lucid-content=&quot;{&amp;quot;t&amp;quot;:&amp;quot;Working at CarGurus \nWe reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&amp;quot;,&amp;quot;m&amp;quot;:[{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;b&amp;quot;,&amp;quot;v&amp;quot;:true,&amp;quot;e&amp;quot;:19},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#000000ff&amp;quot;,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:19.999999999999996,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:19,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#1d1c1dff&amp;quot;,&amp;quot;e&amp;quot;:730},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:20,&amp;quot;e&amp;quot;:730}]}&quot;&gt;&lt;strong&gt;Additional information&lt;/strong&gt; &lt;br&gt;&lt;/span&gt;&lt;span data-lucid-type=&quot;application/vnd.lucid.text&quot; data-lucid-content=&quot;{&amp;quot;t&amp;quot;:&amp;quot;Working at CarGurus \nWe reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&amp;quot;,&amp;quot;m&amp;quot;:[{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;b&amp;quot;,&amp;quot;v&amp;quot;:true,&amp;quot;e&amp;quot;:19},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#000000ff&amp;quot;,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:19.999999999999996,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:19,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#1d1c1dff&amp;quot;,&amp;quot;e&amp;quot;:730},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:20,&amp;quot;e&amp;quot;:730}]}&quot;&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;US employees must provide proof of full vaccination against COVID-19 unless they have an approved medical or religious accommodation. &lt;/span&gt;&lt;span style=&quot;color: #ffffff;&quot;&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;#LI-H&lt;/span&gt;ybrid&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;

Manager, Data Platform Engineering

&lt;p&gt;&lt;strong&gt;Company Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Laronde is pioneering a platform that offers a completely novel way of modulating human biology. Endless RNA™ (eRNA), is a uniquely engineered RNA that can be programmed to express diverse proteins inside the body. It is long lasting, non-immunogenic, allows for repeat dosing, and offers flexibility in formulation and delivery.&lt;/p&gt;
&lt;p&gt;Laronde was founded in 2017 by Flagship Labs, the innovation foundry of Flagship Pioneering. Laronde has raised a record breaking $440 Million in a Series B Financing to advance the development of its eRNA platform. There is a broad pipeline across therapeutic categories with the goal of 100 medicines in 10 years. To learn more, please visit the company’s website at https://www.laronde.bio/about.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Laronde is seeking a highly motivated, talented and detail-oriented software engineer to join our team. In this role you will act as our&amp;nbsp;Internal resource for building and designing internal software needs, taking proof of concept to application.&lt;/p&gt;
&lt;p&gt;This role can be hybrid or fully remote. We are located in Somerville, MA.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Design, architect, develop applications to drive research and manufacturing of eRNA&lt;/li&gt;
&lt;li&gt;Communicate and work effectively with other software engineers and external IT Contractors&lt;/li&gt;
&lt;li&gt;Act as the&amp;nbsp;Internal resource for building and designing internal software needs&lt;/li&gt;
&lt;li&gt;Collaborate with&amp;nbsp;members of other functional teams such manufacturing, research, biology and chemistry&lt;/li&gt;
&lt;li&gt;Ensure application performance, uptime, and scale, maintaining high standards of code quality and thoughtful application design&lt;/li&gt;
&lt;/ul&gt;
&lt;ul&gt;
&lt;li&gt;Work with agile development methodologies&lt;/li&gt;
&lt;li&gt;Writing technical documents&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Required Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;5+ years full stack development experience in a production environment&lt;/li&gt;
&lt;li&gt;Experience with developing in Python and web frameworks such as Django or Flask&lt;/li&gt;
&lt;li&gt;Experience with modern front end frameworks (React/Redux, AngularJS, Vue etc.)&lt;/li&gt;
&lt;li&gt;Knowledge of database systems (mySQL, PostgreSQL)&lt;/li&gt;
&lt;li&gt;Working experience with AWS&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Preferred Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Experience with lab data management workflows and best practices, including familiarity with ELN and LIMS systems is a plus&lt;/li&gt;
&lt;li&gt;Experience with Typescript&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;em&gt;Laronde is &lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;&lt;/em&gt;&lt;em&gt;: Laronde does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Laronde or its employees is strictly prohibited unless contacted directly by Laronde’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Laronde, and Laronde will not owe any referral or other fees with respect thereto&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;

Full Stack Data Engineer

&lt;div class=&quot;content-intro&quot;&gt;&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;Who we are&lt;br&gt;&lt;/strong&gt;&lt;/span&gt;&lt;span class=&quot;normaltextrun&quot; style=&quot;font-size: 12pt;&quot;&gt;&lt;span style=&quot;color: black;&quot;&gt;At CarGurus (NASDAQ: CARG), our mission is to give people the power to reach their destination. We started as a small team of developers determined to bring trust and transparency to car shopping. Since then, our history of innovation and go-to-market acceleration has driven industry-leading growth. In fact, we’re the largest and fastest-growing automotive marketplace, and we’ve been profitable for over 15 years.&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;What we do&lt;/strong&gt;&lt;br&gt;The market is evolving, and we are too, moving the entire automotive journey online and guiding our customers through every step. That includes everything from the sale of an old car to the financing, purchase, and delivery of a new one. Today, tens of millions of consumers visit CarGurus.com each month, and ~30,000 dealerships use our products. But they&#x27;re not the only ones who love CarGurus—our employees do, too. We have a people-first culture that fosters&amp;nbsp;kindness, collaboration, and innovation, and empowers our Gurus with tools to fuel their career growth. Disrupting a trillion-dollar industry requires fresh and diverse perspectives. Come join us for the ride!&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;p&gt;&lt;strong&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Role overview&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;We are looking for a &lt;strong&gt;Data Analyst&lt;/strong&gt; who can further the team’s mission of solving core business problems with data science. As we scale our team’s impact to the organization, we need a SQL and data visualization expert who can help us monitor the performance of the predictive models we build, and help wrangle the data we use to build models.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;What you’ll do&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Write DBT (Data Build Tool) transformations in SQL (Snowflake) that we can use to train and test our machine learning models&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Become an expert in how data is organized at CarGurus, and a go-to source of such information on the data science team&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Build data visualizations, using Looker, that we can use to track the performance of production models&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Become an expert at optimizing SQL queries using our distributed data warehouse (Snowflake)&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Serve as a liaison between the data science team, analytics engineering team, and product analytics team, staying on top of the latest technologies being adopted, and major changes to underlying data schemas&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Build automated tests to ensure the integrity of the data ingested by the data science team (using DBT)&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Work closely with data scientists, and collaborate closely on new data science projects&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;(Optional, depending on interest and math background) Perform and deliver statistical analyses&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;(Optional, depending on interest and python skills) Perform data analyses using tools in the jupyter/pandas python ecosystem, and present findings to team members&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;What you&#x27;ll bring&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;2+ years of experience in a data analytics role&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Expertise in SQL&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Experience with Snowflake or a similar cloud data warehouse is a plus&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Experience with DBT is also a plus&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Experience with Looker, Tableau or similar data visualization tools&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Previous experience with or exposure to statistics and machine learning is preferred&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Experience with scientific python libraries is not vital, but a plus&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Strong organizational skills and code documentation habits&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Excellent listening, interpersonal, written, and oral communication skills&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Transparent communicator who is open, honest, and collaborative&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Driven self-starter, who is accountable for their work, and proud to take ownership&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;&lt;div class=&quot;content-conclusion&quot;&gt;&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;Working at CarGurus&lt;/strong&gt; &lt;br&gt;We reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;We welcome all&lt;/strong&gt;&lt;br&gt;CarGurus strives to be a place to which people can bring the ultimate expression of themselves and their potential—starting with our hiring process. We do not discriminate based on race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation. We foster an inclusive environment that values people for their skills, experiences, and unique perspectives. That’s why we hope you’ll apply even if you don’t check every box listed in the job description. We want to know what only &lt;em&gt;you &lt;/em&gt;can bring to CarGurus.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot; data-lucid-type=&quot;application/vnd.lucid.text&quot; data-lucid-content=&quot;{&amp;quot;t&amp;quot;:&amp;quot;Working at CarGurus \nWe reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&amp;quot;,&amp;quot;m&amp;quot;:[{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;b&amp;quot;,&amp;quot;v&amp;quot;:true,&amp;quot;e&amp;quot;:19},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#000000ff&amp;quot;,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:19.999999999999996,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:19,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#1d1c1dff&amp;quot;,&amp;quot;e&amp;quot;:730},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:20,&amp;quot;e&amp;quot;:730}]}&quot;&gt;&lt;strong&gt;Additional information&lt;/strong&gt; &lt;br&gt;&lt;/span&gt;&lt;span data-lucid-type=&quot;application/vnd.lucid.text&quot; data-lucid-content=&quot;{&amp;quot;t&amp;quot;:&amp;quot;Working at CarGurus \nWe reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&amp;quot;,&amp;quot;m&amp;quot;:[{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;b&amp;quot;,&amp;quot;v&amp;quot;:true,&amp;quot;e&amp;quot;:19},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#000000ff&amp;quot;,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:19.999999999999996,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:19,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#1d1c1dff&amp;quot;,&amp;quot;e&amp;quot;:730},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:20,&amp;quot;e&amp;quot;:730}]}&quot;&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;US employees must provide proof of full vaccination against COVID-19 unless they have an approved medical or religious accommodation. &lt;/span&gt;&lt;span style=&quot;color: #ffffff;&quot;&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;#LI-H&lt;/span&gt;ybrid&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;

Data Science Data Analyst

&lt;div class=&quot;content-intro&quot;&gt;&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;Who we are&lt;br&gt;&lt;/strong&gt;&lt;/span&gt;&lt;span class=&quot;normaltextrun&quot; style=&quot;font-size: 12pt;&quot;&gt;&lt;span style=&quot;color: black;&quot;&gt;At CarGurus (NASDAQ: CARG), our mission is to give people the power to reach their destination. We started as a small team of developers determined to bring trust and transparency to car shopping. Since then, our history of innovation and go-to-market acceleration has driven industry-leading growth. In fact, we’re the largest and fastest-growing automotive marketplace, and we’ve been profitable for over 15 years.&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;What we do&lt;/strong&gt;&lt;br&gt;The market is evolving, and we are too, moving the entire automotive journey online and guiding our customers through every step. That includes everything from the sale of an old car to the financing, purchase, and delivery of a new one. Today, tens of millions of consumers visit CarGurus.com each month, and ~30,000 dealerships use our products. But they&#x27;re not the only ones who love CarGurus—our employees do, too. We have a people-first culture that fosters&amp;nbsp;kindness, collaboration, and innovation, and empowers our Gurus with tools to fuel their career growth. Disrupting a trillion-dollar industry requires fresh and diverse perspectives. Come join us for the ride!&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;p&gt;&lt;strong&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Role Overview&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;On the Data Science team, our goal is to extract insights from voluminous amounts of data and deliver business impact using Data Science and Machine Learning tools. The general problems to solve are unconstrained; we are tasked with collaborating with business partners to drive the company’s innovation and profitability. We are looking for a &lt;strong&gt;Data Scientist&lt;/strong&gt; (Entry Level) who can further the team’s mission of solving core business problems with data science. The current work of the team includes capturing and retaining unique visitors to our site from online search and social media platforms, helping to deliver high-quality data products to the consumer and dealer engineering and product organizations, and helping to craft both long- and short-term strategies for our marketing spend.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;What you&#x27;ll do&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Communicate solutions to both a technical and a lay audience. E.g., what is it, how does it solve the problem, why is it reasonable and what could go wrong&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Analyze data, and support more senior data scientists by performing exploratory data analysis and implementing data pipelines, dashboards, and machine learning solutions&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Help measure the impact of television and radio advertising on online advertising&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Improve CarGurus core algorithms like Instant Market Value (IMV), predicting the probability of a user or customer converting or churning&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Take a curiosity about R&amp;amp;D and the latest ML research, but also don’t hesitate to use a tried-and-true tool when it’s the right one for the job&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Promote and foster an inclusive, transparent, and collaborative culture&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;What you&#x27;ll bring&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Experience working with real datasets, and strong curiosity about deep data analysis – with a desire to investigate large amounts of data and generate insights&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;A basis of knowledge in Statistics and Machine Learning&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Advanced Degree (MS or relevant experience) in one of the following: Data Science, Statistics, Computer Science (ideally with a focus on machine learning) or any quantitative field which makes use of advanced statistical or machine learning techniques&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Prior industry experience in an adjacent field like software engineering or data analytics&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Experience working with or building data pipelines and/or dashboards&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;&lt;div class=&quot;content-conclusion&quot;&gt;&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;Working at CarGurus&lt;/strong&gt; &lt;br&gt;We reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;We welcome all&lt;/strong&gt;&lt;br&gt;CarGurus strives to be a place to which people can bring the ultimate expression of themselves and their potential—starting with our hiring process. We do not discriminate based on race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation. We foster an inclusive environment that values people for their skills, experiences, and unique perspectives. That’s why we hope you’ll apply even if you don’t check every box listed in the job description. We want to know what only &lt;em&gt;you &lt;/em&gt;can bring to CarGurus.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot; data-lucid-type=&quot;application/vnd.lucid.text&quot; data-lucid-content=&quot;{&amp;quot;t&amp;quot;:&amp;quot;Working at CarGurus \nWe reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&amp;quot;,&amp;quot;m&amp;quot;:[{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;b&amp;quot;,&amp;quot;v&amp;quot;:true,&amp;quot;e&amp;quot;:19},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#000000ff&amp;quot;,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:19.999999999999996,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:19,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#1d1c1dff&amp;quot;,&amp;quot;e&amp;quot;:730},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:20,&amp;quot;e&amp;quot;:730}]}&quot;&gt;&lt;strong&gt;Additional information&lt;/strong&gt; &lt;br&gt;&lt;/span&gt;&lt;span data-lucid-type=&quot;application/vnd.lucid.text&quot; data-lucid-content=&quot;{&amp;quot;t&amp;quot;:&amp;quot;Working at CarGurus \nWe reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&amp;quot;,&amp;quot;m&amp;quot;:[{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;b&amp;quot;,&amp;quot;v&amp;quot;:true,&amp;quot;e&amp;quot;:19},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#000000ff&amp;quot;,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:19.999999999999996,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:19,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#1d1c1dff&amp;quot;,&amp;quot;e&amp;quot;:730},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:20,&amp;quot;e&amp;quot;:730}]}&quot;&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;US employees must provide proof of full vaccination against COVID-19 unless they have an approved medical or religious accommodation. &lt;/span&gt;&lt;span style=&quot;color: #ffffff;&quot;&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;#LI-H&lt;/span&gt;ybrid&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;

Data Scientist

&lt;div class=&quot;description content&quot;&gt;
&lt;p&gt;Data Engineers develop modern data architecture approaches to meet key business objectives and provide end-to-end data solutions. You might spend a few weeks with a new client on a deep technical review or a complete organizational review, helping them to understand the potential that data brings to solve their most pressing problems. On other projects, you might be acting as the architect, leading the design of technical solutions, or perhaps overseeing a program inception to build a new product. It could also be a software delivery project where you&#x27;re equally happy coding and tech-leading the team to implement the solution.&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;/div&gt;
&lt;h2 id=&quot;job-responsibilities&quot;&gt;Job responsibilities&lt;/h2&gt;
&lt;div class=&quot;job-responsibilities content&quot;&gt;
&lt;ul&gt;
&lt;li&gt;Take the needs and challenges of a client and formulate the technical roadmap and technology solution that will support their business strategies and goals.&lt;/li&gt;
&lt;li&gt;Provide architectural recommendations, solution and approach given tradeoffs and ability to communicate that to the business.&lt;/li&gt;
&lt;li&gt;Quickly gain an understanding of the landscape of tools and data frameworks so as to recommend next steps, approach (such as real-time streaming, batch, workflows, etc.)&lt;/li&gt;
&lt;li&gt;Credentialize roadmap and architecture&lt;/li&gt;
&lt;li&gt;Enhance Data Engineering capability through coaching, mentoring and leadership&lt;/li&gt;
&lt;li&gt;Co-create and shape strategy and approach to engagements to achieve the desired business outcomes&lt;/li&gt;
&lt;li&gt;Collaborate with other Data Engineer Anchors in the org to learn and share best practices and techniques&lt;/li&gt;
&lt;li&gt;Provide technical leadership in an enterprise environment to ensure delivery of exceptional technical solutions.&lt;/li&gt;
&lt;li&gt;Mentor on approach and execution of solutions, coach on technologies and establishing a team-wide comprehension of solution capabilities and direction.&lt;/li&gt;
&lt;li&gt;Ensure technical expectations of deliverables are met.&lt;/li&gt;
&lt;li&gt;Drive Thought-Leadership on engineering and architectural practices and standards.&lt;/li&gt;
&lt;li&gt;Be an inspiration for innovation to the client.&lt;/li&gt;
&lt;li&gt;Become a trusted and valued partner of the client CIO/CTO and team.&lt;/li&gt;
&lt;li&gt;Maintaining strong expertise and knowledge of current and emerging technologies and products.&lt;/li&gt;
&lt;li&gt;Code! We don’t subscribe to the “post-technical” ivory tower leadership style.&lt;/li&gt;
&lt;li&gt;Assess current state of an organization&lt;/li&gt;
&lt;/ul&gt;
&lt;/div&gt;
&lt;h2 id=&quot;job-qualifications&quot;&gt;Job qualifications&lt;/h2&gt;
&lt;div class=&quot;job-qualifications content&quot;&gt;
&lt;div class=&quot;qualifications inner-content&quot;&gt;
&lt;ul&gt;
&lt;li&gt;You are equally happy coding and leading a team to implement a solution&amp;nbsp;&lt;/li&gt;
&lt;li&gt;You have a track record of innovation and expertise in Data Engineering&amp;nbsp;&lt;/li&gt;
&lt;li&gt;You’re passionate about craftsmanship and have applied your expertise across a range of industries and organizations&lt;/li&gt;
&lt;li&gt;You have a deep understanding of data modeling and experience with data engineering tools and platforms such as Kafka, Spark, and Hadoop&amp;nbsp;&lt;/li&gt;
&lt;li&gt;You have built large-scale data pipelines and data-centric applications using Big Data tooling like Hadoop, Spark, Hive, Oozie, and Airflow in a production setting.&lt;/li&gt;
&lt;li&gt;You’ve tackled challenges of persisting, working with, and exposing metadata from data engineering processes using tools such as Apache Atlas, Cloudera Navigator,&amp;nbsp; &amp;nbsp; etc.&lt;/li&gt;
&lt;li&gt;Hands-on experience building Data Engineering tooling with the Microsoft Azure Data Engineering and Analytics stacks including ADLS, Azure Synapse Analytics, Polybase, ADF, Azure Event Hub, Azure Databricks, Active Directory, and Power BI.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Hands-on experience with event streaming with modern event streaming tooling like Pulsar, Kafka, Kinesis. Understanding of when streaming vs. batch processing is appropriate, and tradeoffs in a given context&lt;/li&gt;
&lt;li&gt;Hands-on experience with MPP query engines like Presto, Dremio, and Spark SQL.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;You are comfortable applying data security strategy to solve business problems&lt;/li&gt;
&lt;li&gt;You are able to contrast the use of managed services vs custom built ones&lt;/li&gt;
&lt;/ul&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;h2 id=&quot;important-things&quot;&gt;Other things to know&lt;/h2&gt;
&lt;div class=&quot;important-things content&quot;&gt;
&lt;p&gt;While we’ve traditionally been a traveling consultancy, travel is not required for this role at the moment. We anticipate the need for travel to our client locations in the future when it’s deemed safe.&lt;/p&gt;
&lt;div class=&quot;inner-content&quot;&gt;
&lt;div&gt;
&lt;div&gt;
&lt;p style=&quot;text-align: left;&quot;&gt;Not quite ready to apply? Or maybe this isn’t the right role for you? That’s OK, you can stay in touch with&amp;nbsp;&lt;a href=&quot;https://www.thoughtworks.com/careers/access?utm_source=apply-jobs&amp;amp;utm_medium=jd&amp;amp;utm_campaign=access-thoughtworks&quot;&gt;AccessThoughtworks&lt;/a&gt;, our learning community (click &quot;&lt;em&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt;contact me about recruitment opportunities&lt;/span&gt;&quot;&lt;/em&gt;&amp;nbsp;to hear about jobs in the future).&lt;/p&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;p style=&quot;color: #7f8c8d;&quot;&gt;&lt;em&gt;It is the policy of Thoughtworks, Inc. to provide a work environment free of discrimination. The Company will take affirmative action to ensure applicants and Thoughtworks employees are treated without regard to race, color, religion, sex/gender, national origin, ethnic origin, veteran or military status, family or marital status, disability, genetic information, age, sexual orientation, gender expression or gender identity. This also includes individuals who are perceived to have any of the aforementioned attributes. Thoughtworks will adhere to all federal, state, and municipal laws and regulations governing employment.&lt;/em&gt;&lt;/p&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;h2 id=&quot;about&quot;&gt;About Thoughtworks&lt;/h2&gt;
&lt;div class=&quot;about content&quot;&gt;
&lt;p&gt;Thoughtworks is a global technology consultancy that integrates strategy, design and engineering to drive digital innovation. For 28+ years, our clients have trusted our autonomous teams to build solutions that look past the obvious. Here, computer science grads come together with seasoned technologists, self-taught developers, midlife career changers and more to learn from and challenge each other. Career journeys flourish with the strength of our cultivation culture, which has won numerous awards around the world. &lt;br&gt;&lt;br&gt;&lt;br&gt;Join Thoughtworks and thrive. Together, our extra curiosity, innovation, passion and dedication overcomes ordinary.&lt;/p&gt;
&lt;/div&gt;

Principal Data Engineer (remote)

&lt;p&gt;&lt;strong&gt;Company Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Laronde is pioneering a platform that offers a completely novel way of modulating human biology. Endless RNA™ (eRNA), is a uniquely engineered RNA that can be programmed to express diverse proteins inside the body. It is long lasting, non-immunogenic, allows for repeat dosing, and offers flexibility in formulation and delivery.&lt;/p&gt;
&lt;p&gt;Laronde was founded in 2017 by Flagship Labs, the innovation foundry of Flagship Pioneering. Laronde has raised a record breaking $440 Million in a Series B Financing to advance the development of its eRNA platform. There is a broad pipeline across therapeutic categories with the goal of 100 medicines in 10 years. To learn more, please visit the company’s website at https://www.laronde.bio/about.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;The Position:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;We are seeking an experienced and driven data engineer who shares our vision of data as a strategic asset in enabling cutting-edge research. In this role you will design and develop cloud-based solutions to advance our goals by ensuring that the data that drives our science is Findable, Accessible, Interoperable, and Reusable. The ideal candidate will have a background working with life science organizations, experience with a variety of scientific data types, and expertise in cloud computing. It’s also essential to be a strong data modeler and coder, with an exceptional ability to deliver near-term value while helping companies plan for the future.&lt;/p&gt;
&lt;p&gt;The successful candidate will act as the glue between wet and dry labs within the company, ensuring that digital solutions meet the needs of bench scientists, computational/data/ML scientists and senior management while aligning with long term strategic objectives. As an early member of a privately held, well-funded, early-stage platform biotechnology company, you will have an opportunity to contribute to building our digital strategy and have significant influence on technology platform development, with many options to apply your skills and talent as the company continues to expand.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Specific Responsibilities&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Create and maintain process maps of all the ways data accumulates and flows into and throughout the company&lt;/li&gt;
&lt;li&gt;Create automated pipelines for various workloads, including raw instrument data processing, computational workflows, and information reporting&lt;/li&gt;
&lt;li&gt;Organize and manage all structured and unstructured scientific data used by the company&lt;/li&gt;
&lt;li&gt;Design data models for entities, assays, and results from scientific experiments and analyses&lt;/li&gt;
&lt;li&gt;Drive consensus and implement standards around scientific research metadata&lt;/li&gt;
&lt;li&gt;Implement scalable, cloud-based solutions to support dramatic increases in data and analysis demands&lt;/li&gt;
&lt;li&gt;Integrate data and metadata from a variety of internal and external sources&lt;/li&gt;
&lt;li&gt;Deliver data products and visualizations to stakeholders&lt;/li&gt;
&lt;li&gt;Establish engineering standards around languages, DevOps and Agile project management&lt;/li&gt;
&lt;li&gt;Assist in the management and administration of our AWS environment&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Minimum Qualifications &lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;MS degree (or BS with equivalent experience) in Bioinformatics, Informatics, Computer Science, Data Science or other related discipline&lt;/li&gt;
&lt;li&gt;3+ years’ experience in data engineering/research informatics in the life sciences&lt;/li&gt;
&lt;li&gt;Demonstrated proficiency with cloud development (AWS strongly preferred) using infrastructure-as-code frameworks&lt;/li&gt;
&lt;li&gt;Proficiency in with modeling and using data stored in relational and NoSQL databases&lt;/li&gt;
&lt;li&gt;Experience integrating multi-omic datasets&lt;/li&gt;
&lt;li&gt;Experience building processes supporting data transformation, data structures, metadata, dependency, and workload management&lt;/li&gt;
&lt;li&gt;Strong DevOps, project management and organization skills&lt;/li&gt;
&lt;li&gt;A people person with an exceptional ability to collaborate with scientists of different backgrounds&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Preferred Qualifications&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Experience with workflow orchestration software (Nextflow, SnakeMake, etc) and deploying it in cloud environments such as AWS Batch&lt;/li&gt;
&lt;li&gt;Experience with ELN/LIMS (Benchling preferred)&lt;/li&gt;
&lt;li&gt;Experience supporting and working with cross-functional teams in a fast-paced environment&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;em&gt;Laronde is &lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;&lt;/em&gt;&lt;em&gt;: Laronde does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Laronde or its employees is strictly prohibited unless contacted directly by Laronde’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Laronde, and Laronde will not owe any referral or other fees with respect thereto&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;

Data Engineer

&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;dhkj5-0-0&quot;&gt;
&lt;p&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;Machine Learning Engineer&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Who We Are&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;FL79 is a platform company built for the climate era. Our mission is to generate leaps in biological and material performance to unlock gigaton-scale climate solutions. We are in a moment in time when machine learning has the potential to exponentially augment the magnitude of human inventiveness to solve the most important challenges associated with protecting the planet. Our team is developing novel computational and experimental technologies to achieve unparalleled industrial speed, scale, and predictability for a more sustainable future. FL79 is looking for motivated, team-oriented problem-solvers who share our passion for accelerating our transition to a sustainable economy.&lt;/p&gt;
&lt;p&gt;FL79 was founded by Flagship Pioneering in the Flagship Labs innovation foundry.&amp;nbsp;&lt;a href=&quot;https://www.flagshippioneering.com/&quot;&gt;Flagship Pioneering&lt;/a&gt;&amp;nbsp;conceives, resources, and builds companies across both human health and sustainability. Flagship has created over 100 scientific ventures resulting in &amp;gt;$200 billion in aggregate value, 500+ issued patents, and &amp;gt;50 clinical trials, spanning&amp;nbsp;&lt;a href=&quot;https://www.modernatx.com/&quot;&gt;Moderna Therapeutics&lt;/a&gt;,&amp;nbsp;&lt;a href=&quot;https://generatebiomedicines.com/&quot;&gt;Generate Biomedicines&lt;/a&gt;,&amp;nbsp;&lt;a href=&quot;https://www.indigoag.com/&quot;&gt;Indigo Ag&lt;/a&gt;,&amp;nbsp;&lt;a href=&quot;https://www.tesseratherapeutics.com/&quot;&gt;Tessera Therapeutics&lt;/a&gt;, and others. We harness science and entrepreneurialism to envision alternative futures, beginning with seemingly unreasonable propositions and navigating to transformational outcomes through an iterative, evolutionary methodology. We call this process&amp;nbsp;&lt;em&gt;“pioneering”.&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;We believe deep integration of data-driven machine learning with experimental approaches will be a core driver of the next generation of defining impact in sustainability, rooted in leveraging novel molecular modalities. We aim to upend the traditional approach to molecular discovery towards one characterized by intentionality, programmability, and speed by developing methods for molecular design and generation that can reliably generalize across functions and applications. We believe that immense impact potential in sustainability can come from diverse scientific and machine learning backgrounds – and are open to all backgrounds with computational excellence.&lt;/p&gt;
&lt;p&gt;To this end, we are seeking a creative and motivated Machine Learning ML Engineer to build the machine learning platform required to drive protein engineering for sustainability and achieve our ambitious goals. You will work across the stack to develop, test, deploy, and maintain ML based software solutions. The successful candidate will work closely with ML Scientists, Computational Biologists, Materials Scientists, and Informatics/IT engineers to implement a scalable platform that rapidly advances our scientific programs.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Design, develop and refine infrastructure for FL79’s ML platform, enabling rapid model development, training, evaluation at scale&lt;/li&gt;
&lt;li&gt;Deploy and monitor cutting-edge ML models and algorithms&lt;/li&gt;
&lt;li&gt;Implement large scale MLOps&amp;nbsp;and data ETL pipelines in a distributed computing environment&lt;/li&gt;
&lt;li&gt;Develop solutions for efficiently performing ML model experimentation and tuning&lt;/li&gt;
&lt;li&gt;Establish data engineering processes and best-practices for data scientists utilizing our ML platform&lt;/li&gt;
&lt;li&gt;Maintain awareness of commercial tools &amp;amp; innovations and champion new solutions internally&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;2+ years experience working in a DevOps or data engineer role using cloud-based infrastructure such as AWS, GCP, or Microsoft Azure&lt;/li&gt;
&lt;li&gt;Well versed in machine learning fundamentals.&amp;nbsp; Experience with deep learning frameworks is desired.&lt;/li&gt;
&lt;li&gt;Proficiency in Python and strong object-oriented design skills coupled with a solid understanding of data structures and algorithms&lt;/li&gt;
&lt;li&gt;Familiarity with workflow orchestration tools such as Airflow, Luigi, or Prefect is desired&lt;/li&gt;
&lt;li&gt;Familiarity with Kubernetes or other container orchestration tools in a production setting&lt;/li&gt;
&lt;li&gt;Demonstrated self-motivation and willingness to dive into complicated data engineering challenges&lt;/li&gt;
&lt;li&gt;Ability to work in a fast-paced environment and strong technical communication skills&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;Flagship Pioneering and our ecosystem companies are&amp;nbsp;&lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/p&gt;
&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

Machine Learning Engineer 

&lt;p&gt;&lt;strong&gt;Company Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Each day, the lives of more than 2 billion people across the globe are impacted by chronic diseases. Moreover, the economic burden on society of treating chronic disease is spinning out of control. Today, this dire situation appears unlikely to change as &amp;gt;95% of global healthcare costs are spent on treating rather than preventing chronic diseases. FL84, Inc. is a privately held early-stage company that is applying advanced biological and computational platforms to discover breakthroughs in detection of and intervention against the etiologies that drive progression from health to disease. Our goal is to leverage our proprietary platforms to disrupt the current approach of treating chronic disease too late. We endeavor to provide true health care rather than sick care to individuals that are at risk of progressing to disease.&lt;/p&gt;
&lt;p&gt;FL84 was founded by Flagship Pioneering, an innovation enterprise dedicated to originating and developing first-in-category life sciences companies. Flagship Pioneering conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, the firm has applied a unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $30 billion in aggregate value. The current Flagship ecosystem comprises 37 transformative companies, including: Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Indigo Agriculture, and Sana Biotechnology.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;We are seeking a creative and motivated MLOps Data Engineer to help us build a machine learning platform capable of disambiguating the mysteries of chronic disease progression. As a member of a larger data science group, she/he/they will work across the stack to develop, test, deploy, and maintain ML based solutions. The successful candidate will work closely with ML scientists, Computational Biologists, and Informatics/IT engineers to implement a scalable platform that rapidly advances our scientific programs.&amp;nbsp;&lt;/p&gt;
&lt;p&gt;The role may also include significant hands-on analyses of clinical data such as electronic health records, insurance claims, laboratory measurements, images, free text, and genetic data. The candidate will work closely with the data science and computational biology teams to accelerate and create insights and novel prediction platforms for different stages of the journey from health to disease.&amp;nbsp; The position will provide a unique opportunity to play a foundational role in the development of FL84’s preclinical platform and explore the complexities of disease progression.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Design, develop and refine infrastructure for FL84’s ML platform, enabling rapid model development, training, evaluation at scale&lt;/li&gt;
&lt;li&gt;Deploy and monitor cutting-edge ML models and algorithms developed by ML team&lt;/li&gt;
&lt;li&gt;Implement large-scale MLOps and data ETL pipelines&lt;/li&gt;
&lt;li&gt;Develop solutions for efficiently performing ML model experimentation and tuning&lt;/li&gt;
&lt;li&gt;Establish data engineering processes and best-practices for data scientists utilizing our ML platform and storage of underlying data&lt;/li&gt;
&lt;li&gt;Cultivate a data-centric and process-oriented company philosophy by helping to maintain best practices for software development, data management, and infrastructure&lt;/li&gt;
&lt;li&gt;Monitor and evaluate new and emerging technologies and models and identify opportunities for collaboration within Flagship Pioneering companies, academia, and third parties&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Basic Requirements:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;3+ year’s experience working in a DevOps or data engineer role using AWS cloud-based infrastructure&lt;/li&gt;
&lt;li&gt;Proficiency in Python and strong object-oriented design skills coupled with a solid understanding of data structures and algorithms&lt;/li&gt;
&lt;li&gt;Familiarity with implementing large-scale data ETL pipelines or container orchestration tools in a production setting&lt;/li&gt;
&lt;li&gt;Demonstrated self-motivation and willingness to dive into complicated data engineering challenges&lt;/li&gt;
&lt;li&gt;Experience in Big Data / Spark / Hadoop development&lt;/li&gt;
&lt;li&gt;Ability to work in a fast-paced environment and strong technical communication skills&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Preferred Requirements&lt;em&gt;:&lt;/em&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;AWS credentials or equivalent experience&lt;/li&gt;
&lt;li&gt;Familiar with multiple of the following areas/topics: regression models, regularization, recurrent neural networks, graph neural networks, LSTMs, or CNNs&lt;/li&gt;
&lt;li&gt;Experience working with reference genetic and other biological databases and datasets (e.g., UK Biobank, TCGA, CMAP, LINCS) is a strong plus&lt;/li&gt;
&lt;li&gt;Ability to Google error messages and seek resolution from self-investigation&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;Flagship Pioneering is committed to&amp;nbsp;&lt;strong&gt;equal employment opportunity&lt;/strong&gt;&amp;nbsp;regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;&lt;em&gt;Recruitment &amp;amp; Staffing Agencies:&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;&amp;nbsp;Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/p&gt;

FL84: Data Engineer, Machine Learning Ops

&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;dhkj5-0-0&quot;&gt;
&lt;p&gt;&lt;strong&gt;What if&lt;/strong&gt;… you could tell the story of an organization that conceives, creates, resources, and develops first-in-category bioplatform companies to transform human health and sustainability?&lt;/p&gt;
&lt;p&gt;Since its launch in 2000 Flagship Pioneering has, through its Flagship Pioneering Labs unit, applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $130 billion in aggregate value. To date, Flagship has deployed over $2.5 billion in capital toward the founding and growth of its pioneering companies alongside more than $19 billion of follow-on investments from other institutions.&lt;/p&gt;
&lt;p&gt;Flagship Pioneering presents compelling opportunities for impact-focused technology professionals:&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;The Flagship Labs ecosystem is composed of new and growing companies with widely varying needs that span all aspects of technology, presenting incredible opportunities for learning and development.&lt;/li&gt;
&lt;li&gt;Flagship creates new companies that operate without the burden of legacy systems or technical debt. Individuals that understand the technical opportunities and challenges in company growth will have the opportunity to positively impact and influence the trajectory of dozens of companies.&lt;/li&gt;
&lt;li&gt;Flagship believes that the sophisticated use of modern digital and data technologies is a strategic differentiator for companies, with the potential to significantly alter their research, productivity, market position and long-term success. To deliver on this mission, Flagship seeks individuals who have a proven track record of solving enterprise-scale challenges while thriving in a dynamic startup culture.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Position Summary&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;We are looking for a builder - an exceptional Principal Engineer to join our team as we build our next generation cloud architecture, the Flagship Digital Backbone.&lt;/p&gt;
&lt;p&gt;The Principal AWS Data Engineer will report to the Senior Director, Cloud Architecture and be part of the Engineering Data &amp;amp; Systems team, which supports Scientific Systems, Data, and Data Science needs for both Flagship Pioneering and Enterprise companies. This role will have responsibility for providing cloud-based data solutions, best practices, and guidance to Flagship Pioneering and enterprise companies and be a key member in designing and building our Digital Backbone.&lt;/p&gt;
&lt;p&gt;A typical day may involve developing API-centric data flow patterns between systems, authoring reference implementations for AWS scientific computing workloads, automating bioinformatics pipelines to analyze large datasets, creating crawlers for extracting, transforming, and loading datasets (ETL), generally making it easier for data scientists to use their cloud environments and tools.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Collaborate with architects and technical leadership on the design and creation of a digital backbone for our companies&lt;/li&gt;
&lt;li&gt;Develop ETL solutions for a federated datalake architecture&lt;/li&gt;
&lt;li&gt;Develop high quality, production ready code&lt;/li&gt;
&lt;li&gt;Work in a collaborative CI/CD software development environment&lt;/li&gt;
&lt;li&gt;Build cloud-based solutions with AWS CloudFormation and CDK&lt;/li&gt;
&lt;li&gt;Refine methods of data ingestion from&amp;nbsp;external sources (e.g. CROs, data owners)&lt;/li&gt;
&lt;li&gt;Provide expert guidance, code examples and reference implementations for a variety of AWS workloads&lt;/li&gt;
&lt;li&gt;Support portfolio companies on the pragmatic implementation of FAIR principles&lt;/li&gt;
&lt;li&gt;May lead small teams of consultants to deliver solutions&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Qualifications &amp;amp; Experience&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;3+ years data engineering experience&lt;/li&gt;
&lt;li&gt;Familiarity with Datalake and Lakehouse architectures&lt;/li&gt;
&lt;li&gt;Experience with Extract, Transform, Load (ETL) pipelines&lt;/li&gt;
&lt;li&gt;Experience working with DataFrames, via Pandas or PySpark&lt;/li&gt;
&lt;li&gt;Professional AWS certifications or equivalent experience.&lt;/li&gt;
&lt;li&gt;Expertise with various database technologies, including SQL, NoSQL, graph dbs&lt;/li&gt;
&lt;li&gt;Experience modeling data&lt;/li&gt;
&lt;li&gt;Proficiency with python, shell scripting, IaC, pipeline frameworks (e.g. NextFlow) and DevOps best practices&lt;/li&gt;
&lt;li&gt;A people person with an exceptional ability to collaborate with users of different backgrounds&lt;/li&gt;
&lt;/ul&gt;
&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;Flagship Pioneering and our ecosystem companies are &lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;&amp;nbsp;&lt;/div&gt;
&lt;/div&gt;
&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

Principal AWS Data Engineer

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&lt;p&gt;&lt;strong&gt;Company Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;What if&lt;/strong&gt; you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability? Flagship Labs 72 is an early-stage biotechnology company with an ambitious and exciting mission: to reimagine drug discovery and vaccine design through the integration of computational and experimental innovation applied to protein engineering. The company is developing a revolutionary approach to this challenge and recruiting a team of top-tier scientists and engineers to build a powerful, first-in-category R&amp;amp;D platform. Flagship Labs 72 is a product of Flagship Pioneering’s venture creation engine, which has also given rise to companies such as Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), and Editas Medicines (NASDAQ: EDIT). Since Flagship’s founding in 2000, the firm has originated and fostered the development of more than 100 scientific ventures, resulting in over $34 billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary&lt;/strong&gt;:&lt;/p&gt;
&lt;p&gt;Flagship Labs 72 is seeking a Director of Computational Biology to bring their expertise and leadership to a rapidly growing team of bioinformaticians, computational biologists, and software engineers developing data infrastructure, algorithms, and computational tools to support the company’s discovery and translation platforms. You will be responsible for guiding strategic decision making, building the team, and interfacing with scientific and senior leaders across the organization. You will join an interdisciplinary and collaborative group at the interface of computational immunology and protein design. The successful candidate will bring experience in the design and execution of next-generation or third-generation sequencing experiments and will drive the planning and analysis of massively parallel assays enabled by the company’s innovative bioplatform. Experience with the interpretation of massively parallel assays and/or immune repertoire datasets is preferred. There will be an expectation for the selected candidate to be able to come to the lab/office at least 3 days a week.&lt;/p&gt;
&lt;h3&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/h3&gt;
&lt;ul&gt;
&lt;li&gt;Lead our computational biology team to build pipelines and analytical tools that scale our discovery platform&lt;/li&gt;
&lt;li&gt;Grow and manage the computational biology team while instilling software best practices enabling reproducibility and scalability&lt;/li&gt;
&lt;li&gt;Explore, design, and implement algorithms for the analysis of massively parallel assays and immune repertoires&lt;/li&gt;
&lt;li&gt;Collaborate closely with both our drug design and experimental teams to make key strategic decisions and ensure the successful transfer of information between groups&lt;/li&gt;
&lt;li&gt;Formulate the company’s computational strategy and monitor progress toward key strategic goals&lt;/li&gt;
&lt;/ul&gt;
&lt;h3&gt;&lt;strong&gt;Basic Qualifications:&lt;/strong&gt;&lt;/h3&gt;
&lt;ul&gt;
&lt;li&gt;MS/PhD in computational biology or a related field and 8+ years of related experience including 4+ years of team or project leadership&lt;/li&gt;
&lt;li&gt;Experience managing a team of computational biologists, bioinformaticians, and/or software engineers&lt;/li&gt;
&lt;li&gt;Experience developing analysis pipelines for next-generation or third-generation sequencing data&lt;/li&gt;
&lt;li&gt;Exceptional knowledge of best practices in software development and analysis&lt;/li&gt;
&lt;li&gt;Ability to collaborate with scientists across diverse areas of expertise&lt;/li&gt;
&lt;/ul&gt;
&lt;h3&gt;&lt;strong&gt;Preferred Qualifications:&lt;/strong&gt;&lt;/h3&gt;
&lt;ul&gt;
&lt;li&gt;Experience scaling computational teams&lt;/li&gt;
&lt;li&gt;Experience with protein or antibody engineering&lt;/li&gt;
&lt;li&gt;Experience analyzing massively parallel assay data&lt;/li&gt;
&lt;li&gt;Experience with immune repertoire analysis&lt;/li&gt;
&lt;li&gt;Familiarity with laboratory information management systems and/or electronic laboratory notebooks&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Values and Behaviors&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Flagship is an experiment in institutional, entrepreneurial, innovation practiced in the context of a small company with an insurgent mindset. We are seeking individuals with an entrepreneurial spirit, strong communication skills, and comfort working in and contributing to a dynamic and cross-functional team environment. The level of the role will be commensurate with the education and years of experience of the identified candidate.&lt;/p&gt;
&lt;p&gt;Flagship Pioneering and our ecosystem companies are &lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/p&gt;
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&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;&amp;nbsp;&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

Director, Computational Biology

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&lt;p&gt;&lt;strong&gt;Company Summary:&amp;nbsp;&lt;/strong&gt;&lt;br&gt;Ring Therapeutics Inc. is a privately held, early-stage biotechnology company pioneering a novel form of gene therapy by exploiting a family of naturally occurring commensal viruses to create the first re-dosable and targetable viral vector. This approach enables a powerful new class of tropic, persistent, non-integrating vectors that overcome the immunogenicity, and limited tropism of existing gene therapy vectors. Ring Therapeutics is leveraging this versatile technology to develop a broad pipeline of novel, targeted medicines for disease with high unmet medical need.&lt;br&gt;&lt;br&gt;Ring Therapeutics was founded by Flagship Pioneering, focused on launching breakthrough companies based on internally conceived innovations and insights. Flagship Pioneering has created over 40 groundbreaking companies over the past fifteen years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Seres Therapeutics (MCRB), Syros Pharmaceuticals (SYRS), Rubius Therapeutics (RUBY), Axcella Health, Evelo Biosciences (EVLO), and Indigo Agriculture.&lt;br&gt;&lt;br&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;br&gt;Ring Therapeutics is seeking an Associate Director with a background in nucleic acid production and analytics to build and lead a Nucleic Acid Biochemistry team.&amp;nbsp; The successful candidate will build and manage a team of Scientists and Research Associates for developing novel vector payloads and developing assays for characterizing vector loading of said payloads. &amp;nbsp;The candidate will interface with our internal cloning, virology and protein biochemistry teams generate assays required to demonstrate complete transgene packaging by vectors. &amp;nbsp;The candidate will also work closely with our Technical Operations and Analytical Development teams to aid in the generation of GMP-compatible release assays. This will be a great opportunity to participate in cutting-edge viral genome engineering and novel payload design. We are searching for enthusiastic and highly motivated individuals who are comfortable multitasking and working both with a team and independently on various aspects of the viral platform development.&lt;br&gt;&lt;br&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Build and lead a team responsible for generating, purifying and characterizing nucleic acid reagents at research scale (mRNA and ssDNA).&lt;/li&gt;
&lt;li&gt;Build and lead a team responsible for developing assays to demonstrate complete packaging of novel nucleic acid payloads in our vector platform (Capillary Electrophoresis (CE), Southern and Northern blotting, SEC-MALS).&lt;/li&gt;
&lt;li&gt;Willing to aid in benchwork, contributing to the research while teaching junior associates new analytical techniques.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Ph.D. in structural virology, biochemistry, or related field.&lt;/li&gt;
&lt;li&gt;5+ years of industry experience in pharmaceutical, or biotechnology experience.&lt;/li&gt;
&lt;li&gt;Experience managing a team of Scientists (Ph.Ds.) and Associates.&lt;/li&gt;
&lt;li&gt;Demonstrated expertise in generating nucleic acids at research scale for &lt;em&gt;in vivo&lt;/em&gt; studies (generating mRNA or circular enclosed DNA for LNP or vector delivery).&lt;/li&gt;
&lt;li&gt;Familiarity with assays to quantify vector packaging (AAV, etc.) a plus.&lt;/li&gt;
&lt;li&gt;Excellent communication and presentation skills, capable of conveying technical information in a clear and thorough manner.&lt;/li&gt;
&lt;li&gt;Comfortable delivering against challenging timeline commitments.&lt;/li&gt;
&lt;/ul&gt;
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&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;Flagship Pioneering and our ecosystem companies are &lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;&amp;nbsp;&lt;/div&gt;
&lt;/div&gt;
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&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

Associate Director, Nucleic Acid Biochemistry

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&lt;p&gt;&lt;strong&gt;What if…&lt;/strong&gt; you could join an organization that is discovering and developing an entirely new class of medicines, one that leverages both chemistry and biology, to overcome many of the challenges faced by current therapeutics today?&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Company Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Flagship Labs 83, Inc. (FL83) is a privately held, early-stage biotechnology company on a mission to make biology better through chemistry. We are pioneering the development of a transformational new class of medicines, called Artificial Biologics™, that is unlocked by novel synthetic and computational technologies. We seek an exceptional Senior ML Engineer to join our entrepreneurial and innovation-driven organization.&lt;/p&gt;
&lt;p&gt;FL83 was founded in Flagship Pioneering’s venture creation engine, where companies such as Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), and Generate Biomedicines were conceived and created. Since Flagship’s founding in 2000, the firm has originated and fostered the development of more than 100 scientific ventures resulting in over $34 billion in aggregate value, more than 500 issued patents and more than 50 clinical trials for novel therapeutic agents.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Flagship Labs 83 is looking for a creative and motivated &lt;strong&gt;Senior ML Engineer&lt;/strong&gt; to establish our Artificial Biologics™, Computational Protein Design team. As part of the early scientific team, this individual will be instrumental in building the Computational Protein Design platform, using data-driven approaches to tackle Artificial Biologics™ design challenges and develop impactful new medicines. The ideal candidate will have experience applying state-of-the-art machine learning and computational methods to guide the generation and application of unique peptides and protein design.&amp;nbsp;A successful candidate will be an excellent collaborator working closely with our Platform Development and Biology teams to implement and execute rapid design-build-test cycles and optimized methods.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Leading and collaborating on the development of computational methods to predict and understand how peptide and protein structure impacts biologically relevant properties. You will use both modern machine learning methods and classical computational approaches.&lt;/li&gt;
&lt;li&gt;Working closely with Platform Development and Biology teams to integrate a tight design-build-test cycle leveraging FL83’s proprietary technology&lt;/li&gt;
&lt;li&gt;Prototyping APIs, writing beautiful code and ensuring a great user experience for the tools you create.&lt;/li&gt;
&lt;li&gt;Working in a collaborative CI/CD software development environment, including use of git, participating in code reviews, and independent development of robust code.&lt;/li&gt;
&lt;li&gt;Building and maintaining machine learning and data infrastructure.&lt;/li&gt;
&lt;li&gt;Working within an entrepreneurial, collaborative, and interdisciplinary team to actively contribute to creating, shaping, and executing the vision of the company&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Undergraduate or Master&#x27;s degree in bioinformatics, computer science, mathematics, physics or related field and 4+ years of experience is required&lt;/li&gt;
&lt;li&gt;Practical experience in Machine Learning models and Software Engineering&lt;/li&gt;
&lt;li&gt;Proficient in Python and experience in using deep learning libraries (i.e. PyTorch)&lt;/li&gt;
&lt;li&gt;Experience with cloud computing (i.e. AWS) and data pipelining tools (i.e. Nextflow, Airflow)&lt;/li&gt;
&lt;li&gt;Demonstrated ability to communicate and work effectively with a cross-disciplinary team, external contractors, and members of other multifunctional teams (i.e. data science, translational biology, chemistry, etc.) within and outside of the Flagship ecosystem&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;Flagship Pioneering and our ecosystem companies are&amp;nbsp;&lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt;&amp;nbsp;regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;*: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.*&lt;/p&gt;
&lt;/div&gt;

FL83: Senior Machine Learning Engineer

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&lt;p&gt;&lt;strong&gt;Title: Principal/Senior Scientist, Computational Biology&amp;nbsp;&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;What if…&lt;/strong&gt;you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?&lt;/p&gt;
&lt;p&gt;Radial Therapeutics, Inc. is a privately held, well-funded, early-stage biotechnology company leveraging novel insights in RNA biology. Radial Therapeutics’s proprietary platform identifies novel disease targets and develops new therapeutic modalities targeting RNA, providing new strategies to treat or cure a range of diseases including rare genetic diseases, neurological diseases, and cancers.&lt;/p&gt;
&lt;p&gt;Radial Therapeutics, Inc. was founded in Flagship’s venture creation engine, where companies such as Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), and Editas Medicines (NASDAQ: EDIT) were conceived and created.&amp;nbsp; Since Flagship’s founding in 2000, the firm has originated and fostered the development of more than 100 scientific ventures, resulting in over $34 billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents.&amp;nbsp;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;We are seeking a Senior or Principal Scientist in Computational Biology to join a multidisciplinary team of scientists including experimental biologists, medicinal chemists and AI scientists. You will pioneer the development of sophisticated statistical analysis techniques on a variety of large datasets to answer key biological questions and generate testable hypotheses in the area of RNA biology. This exciting role requires broad expertise across RNA biology, data engineering, bioinformatics data processing with emphasis on advanced statistical analysis and data-driven modeling to generate testable hypotheses. Operationally, this position will require close collaboration with experimental biologists and will act a key interface between AI scientists and experimental biology.&lt;/p&gt;
&lt;p&gt;Successful candidates will be driven, nimble and strive to positively impact Radial Therapeutics through their deep expertise in data engineering, advanced high-dimensional data analysis and computational modeling.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Responsibilities&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Translate biological questions into computational problems&lt;/li&gt;
&lt;li&gt;Identify, internalize, and mine public and in-house next generation sequencing data by developing or applying existing pipelines&lt;/li&gt;
&lt;li&gt;Build and advance our computational and data-driven modeling platform to reduce raw data from sequencing approaches to extract key insights&lt;/li&gt;
&lt;li&gt;Develop and implement advanced statistical analysis and modeling approaches in order to test hypotheses and generate testable predictions&lt;/li&gt;
&lt;li&gt;Create concise data visualizations and communicate complex results to an interdisciplinary audience&lt;/li&gt;
&lt;li&gt;Constantly and rapidly prototype ideas to reach go/no-go decisions&lt;/li&gt;
&lt;li&gt;Actively participate in designing optimal experimental approaches by working closely with the experimental team&lt;/li&gt;
&lt;li&gt;Actively contribute to designing high-throughput data generation experiments and process the generated data to fuel models built by our AI team&amp;nbsp; &amp;nbsp;&amp;nbsp;&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Mentor and build a computational biology team&lt;/li&gt;
&lt;li&gt;Actively contribute to creating, shaping and executing the scientific and strategic vision of the company&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Requirements&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;PhD in Computational Biology, Computer Science, Mathematics, Statistics or a related field&lt;/li&gt;
&lt;li&gt;Proven track record of excellence in computational science, statistics and data-driven modeling with an emphasis on biological applications in RNA biology or a related domain&lt;/li&gt;
&lt;li&gt;6+ years industry experience&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Deep understanding of high-dimensional statistical data analysis and algorithm development, as it relates to modeling biological processes using a wide variety of next-generation sequencing techniques&lt;/li&gt;
&lt;li&gt;Strong experience in processing and statistical analysis of biological sequencing data such as RNAseq, CLIPseq, SHAPEseq, DMSMaPseq, ATACseq, SELEX, and/or single-cell transcriptomics to facilitate data-driven hypothesis generation&lt;/li&gt;
&lt;li&gt;Experience in modeling 2D or 3D RNA structure is preferred but not required&lt;/li&gt;
&lt;li&gt;Strong programming skills in a variety of low-level languages such as C and C++, as well as high-level languages such as Python&lt;/li&gt;
&lt;li&gt;Strong expertise in key Python software libraries such pandas, dask, numpy, sklearn, biopython and other relevant data science libraries&lt;/li&gt;
&lt;li&gt;Experience developing data processing, engineering and statistical analysis workflows using AWS services such as S3, EC2, ECS, AWS Batch, NextFlow&lt;/li&gt;
&lt;li&gt;Excellent data visualization and communication skills with the ability to explain complex concepts to a general scientific audience and drive decision-making&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;More&amp;nbsp;About Flagship Pioneering&lt;/strong&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;We are creative optimists and we would love for you to consider joining our team!&amp;nbsp;&amp;nbsp;See&amp;nbsp;&lt;a href=&quot;https://www.flagshippioneering.com/join/roles&quot;&gt;all our open opportunities&lt;/a&gt;&amp;nbsp;across Flagship Pioneering’s Ecosystem!&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;a href=&quot;https://www.flagshippioneering.com/&quot;&gt;Flagship Pioneering&lt;/a&gt; conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, the firm has applied a unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $180 billion in aggregate value. To date, Flagship is backed by more than $4.4 billion of aggregate capital commitments, of which over $1.9 billion has been deployed toward the founding and growth of its pioneering companies alongside more than $10 billion of follow-on investments from other institutions. The current Flagship ecosystem comprises 41 transformative companies, including:&amp;nbsp;&amp;nbsp;Axcella Health (NASDAQ: AXLA), Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO),&amp;nbsp;&amp;nbsp;Foghorn Therapeutics, Indigo Ag, Kaleido Biosciences (NASDAQ: KLDO), Moderna (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology, Seres Therapeutics (NASDAQ: MCRB), and Syros Pharmaceuticals (NASDAQ: SYRS).&amp;nbsp;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;We believe pioneering is best done by teams, and that it is a process that can be taught, learned, and replicated.&amp;nbsp;&amp;nbsp;Learn more about&amp;nbsp;our&amp;nbsp;&lt;a href=&quot;https://www.flagshippioneering.com/process&quot;&gt;Company Creation Model&lt;/a&gt;.&amp;nbsp;&lt;/p&gt;
&lt;p&gt;Can Breakthrough Innovations Be Made Systematically&lt;a href=&quot;https://www.flagshippioneering.com/stories/can-innovations-be-made-systematically-a-conversation-with-noubar-afeyan&quot;&gt;? A Conversation With Noubar Afeyan&lt;/a&gt;, Flagship Pioneering’s CEO.&amp;nbsp;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;Flagship Pioneering&amp;nbsp;and&amp;nbsp;our ecosystem companies are committed to&amp;nbsp;&lt;strong&gt;equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;&lt;em&gt;Recruitment &amp;amp; Staffing Agencies:&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;&amp;nbsp; Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates.&amp;nbsp; The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team.&amp;nbsp;&amp;nbsp; Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&amp;nbsp;&lt;/p&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

Principal/Senior Scientist, Computational Biology 

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&lt;p&gt;&lt;strong&gt;Company Summary:&lt;br&gt;&lt;br&gt;&lt;/strong&gt;Ring Therapeutics Inc. is a privately held, early-stage biotechnology company pioneering a novel form of gene therapy by exploiting a family of naturally occurring commensal viruses to create the first re-dosable and targetable viral vector. This approach enables a powerful new class of tropic, persistent, non-integrating vectors that overcome the immunogenicity, and limited tropism of existing gene therapy vectors. Ring Therapeutics is leveraging this versatile technology to develop a broad pipeline of novel, targeted medicines for disease with high unmet medical need.&lt;br&gt;&lt;br&gt;Ring Therapeutics was founded by Flagship Pioneering, focused on launching breakthrough companies based on internally conceived innovations and insights. Flagship Pioneering has created over 40 groundbreaking companies over the past fifteen years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Seres Therapeutics (MCRB), Syros Pharmaceuticals (SYRS), Rubius Therapeutics (RUBY), Axcella Health, Evelo Biosciences (EVLO), and Indigo Agriculture.&lt;br&gt;&lt;br&gt;&lt;strong&gt;Position Summary:&lt;br&gt;&lt;br&gt;&lt;/strong&gt;Ring Therapeutics is seeking an Associate Director with a background in structural biology and familiar with computational de novo protein design to build and lead a Protein Engineering team. The successful candidate will build and manage a team of Scientists and Research Associates for developing novel vector payloads and modified vector capsid proteins. The candidate will interface with our internal cloning and protein biochemistry teams and external CROs to design, generate and test novel vector payloads, including but not limited to antibody fragments and nanobodies. Furthermore, the candidate will be involved with optimizing the current viral vector capsid protein to improve vector assembly an direct tropism. This will be a great opportunity to participate in cutting-edge structural virology, viral genome engineering, and novel payload design. We are searching for enthusiastic and highly motivated individuals who are comfortable multitasking and working both with a team and independently on various aspects of the viral platform development.&lt;br&gt;&lt;br&gt;&lt;strong&gt;Key Responsibilities:&lt;br&gt;&lt;br&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Build and lead a team responsible for engineering novel vector payloads and optimized vector capsid proteins&lt;/li&gt;
&lt;li&gt;Build and lead a team responsible for developing functional assays to test novel payload function, including expression testing, binding assays (Octet/SPR), and vaccine antigen immunogenicity (ELISA).&lt;/li&gt;
&lt;li&gt;Willing to aid in benchwork, contributing to the research while teaching junior associates new analytical techniques.&lt;br&gt;&lt;br&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Qualifications:&lt;br&gt;&lt;br&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Ph.D. in structural virology, biochemistry, or related field.&lt;/li&gt;
&lt;li&gt;5+ years of industry experience in pharmaceutical, or biotechnology experience.&lt;/li&gt;
&lt;li&gt;Experience managing a team of Scientists (Ph.D.s) and Associates.&lt;/li&gt;
&lt;li&gt;Demonstrated expertise in computational protein design (Rosetta, AlphaFold).&lt;/li&gt;
&lt;li&gt;Familiarity with antibody fragment or nanobody design a plus&lt;/li&gt;
&lt;li&gt;Familiarly with machine learning a plus.&lt;/li&gt;
&lt;li&gt;Excellent communication and presentation skills, capable of conveying technical information in a clear and thorough manner.&lt;/li&gt;
&lt;li&gt;Comfortable delivering against challenging timeline commitments.&lt;br&gt;&lt;br&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;Flagship Pioneering and our ecosystem companies are&amp;nbsp;&lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt;&amp;nbsp;regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;br&gt;&lt;br&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/p&gt;
&lt;/div&gt;

Associate Director, Protein Biochemistry

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&lt;p&gt;&lt;strong&gt;Company Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;FL70, Inc is one of the latest companies founded through Flagship Pioneering’s venture creation engine, where companies such as&lt;em&gt;&amp;nbsp;Moderna&amp;nbsp;&lt;/em&gt;Therapeutics,&lt;em&gt;&amp;nbsp;Rubius&amp;nbsp;&lt;/em&gt;Therapeutics, and&lt;em&gt;&amp;nbsp;Evelo&amp;nbsp;&lt;/em&gt;Therapeutics were conceived and created. Since Flagship’s founding in 2000, the firm has originated and fostered the development of nearly 100 scientific ventures resulting in $19+ billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents. FL70 is integrating the latest developments in molecular biology and plant biology to create a new platform technology that enables adaptive, targeted, and sustainable solutions in agriculture.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Sum&lt;/strong&gt;&lt;strong&gt;mary&lt;/strong&gt;&lt;strong&gt;:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;We are seeking a curious and inspired Computational Biologist with expertise in new functional gene discovery and &lt;em&gt;de novo &lt;/em&gt;genome assembly from environmental sequencing data to join our passionate team at FL70 to revolutionize agriculture. You will tackle computational challenges to discover novel microorganisms and viruses, and interface directly with molecular engineering teams to test your discoveries. In conjunction with experimentalists, you will analyze next-generation sequencing data from an ecological and functional perspective to build our platform technology. Your role will involve aspects of data management/infrastructure to build automated/standalone pipelines. You will be a key player to translate early-stage discovery to empirical lab validation. You thrive in a fast-paced entrepreneurial environment as an integral part of a highly collaborative and interdisciplinary team. The level of the role will be determined by education and years of experience.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key Responsibilities:&amp;nbsp;&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Analyze next-generation sequencing data to discover novel sequences of interest&lt;/li&gt;
&lt;li&gt;Assemble and annotate metagenomic and metatranscriptomic data, and develop new computational methods or leverage existing methodologies&lt;/li&gt;
&lt;li&gt;Create and maintain pipelines for processing high-throughput next-generation sequencing data for comparative genomics and gene discovery studies&lt;/li&gt;
&lt;li&gt;Develop and refine systems to aggregate and prioritize discovered sequences for empirical validation and testing by our molecular engineering and cloning teems&lt;/li&gt;
&lt;li&gt;Maintain scientific and technical expertise through familiarity with scientific literature, attending conferences, and developing relationships with thought leaders&lt;/li&gt;
&lt;li&gt;Work closely with an entrepreneurial, highly-collaborative, interdisciplinary team and actively contribute to creating, shaping, and executing the scientific and strategic vision of the company&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;&amp;nbsp;&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Minimum Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;PhD in Computational Biology, RNA Biology, Bioinformatics, Computer Science, Viral or Microbial Ecology, Comparative Genomics, or related field&lt;/li&gt;
&lt;li&gt;Strong expertise in new functional gene discovery from shotgun sequencing datasets, with experience evaluating multiple tools and approaches&lt;/li&gt;
&lt;li&gt;Deep understanding of genomic and transcriptomic assembly methods.&lt;/li&gt;
&lt;li&gt;Extensive experience interfacing with molecular teams to streamline wet lab and computational discovery and functional assay analysis&lt;/li&gt;
&lt;li&gt;Strong programming experience in Python or R&lt;/li&gt;
&lt;li&gt;A strong self-starter, independent thinker, with attention to detail&lt;/li&gt;
&lt;li&gt;Demonstrated industry experience or academic achievement, as evidenced by publications in high impact journals&lt;/li&gt;
&lt;li&gt;Excellent communication and presentation skills, capable of conveying technical information in a clear and thorough manner&lt;/li&gt;
&lt;li&gt;Confident, execution-focused, and team-oriented to thrive in an entrepreneurial environment&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Preferred Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Proficiency in creating reproducible workflows using Nextflow and Docker, and working in cloud computing environments such as Amazon Web Services&lt;/li&gt;
&lt;li&gt;Experience in creating dashboards or other utilities to allow biologists to investigate data independently&lt;/li&gt;
&lt;li&gt;Experience establishing automated pipelines for hybrid assembly and analysis for both long-read (Pac Bio and Nanopore) and short-read (Illumina) NGS sequencing technology&lt;/li&gt;
&lt;li&gt;Industry experience with project management and big data management&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Location: &lt;/strong&gt;Cambridge, MA&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;More About Flagship Pioneering&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Flagship Pioneering conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, the firm has, through its Flagship Labs unit, applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $50B in aggregate value. To date, Flagship has deployed over $2.2B in capital toward the founding and growth of its pioneering companies alongside more than $18B of follow-on investments from other institutions. The current Flagship ecosystem comprises 41 transformative companies, including Axcella Health (NASDAQ: AXLA), Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO), Foghorn Therapeutics (NASDAQ: FHTX), Indigo Ag, Kaleido Biosciences (NASDAQ: KLDO), Moderna (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology, Seres Therapeutics (NASDAQ: MCRB), and Sigilon Therapeutics (NASDAQ: SGTX).&lt;/p&gt;
&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;Flagship Pioneering and our ecosystem companies are &lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;&amp;nbsp;&lt;/div&gt;
&lt;/div&gt;
&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

Computational Biologist: Viral Ecology and Genomics

&lt;p&gt;&lt;strong&gt;Company Details:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;FL92/93 Inc. is a privately held, well-funded, early-stage biotechnology company that is pioneering a novel transformative RNA-based therapeutic approach.&lt;/p&gt;
&lt;p&gt;FL92/93 was founded by Flagship Pioneering, a team of entrepreneurial scientists that conceives, creates, resources, and grows first-in-category life sciences companies. Since 2000, Flagship has created over 100 groundbreaking companies that are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna Therapeutics (NASDAQ:MRNA), Seres Therapeutics (NASDAQ:MCRB), Syros Pharmaceuticals (NASDAQ:SYRS), Rubius Therapeutics (NASDAQ:RUBY), Axcella Health (NASDAQ:AXLA), Evelo Biosciences (NASDAQ:EVLO), Laronde, Tessera, Alltrna, and Indigo Agriculture.&lt;/p&gt;
&lt;p&gt;F92/93 Inc. is a highly dynamic, entrepreneurial, and innovation-driven organization seeking to hire an exceptional RNA scientist to join our development team. FL92/93 is seeking a scientist (or senior scientist) with a strong background in nucleic acid manipulation and delivery strategies to join our expanding team as a part of our development group. The position requires broad technical experience that spans molecular biology, synthetic biology, and biophysics, with a strong emphasis on critical thinking, multitasking, and the ability to learn new techniques. The successful candidate will help lead and support multidisciplinary project teams focused on the engineering and development of new therapeutic modalities, including nucleic acids, peptides, proteins, cells, and various conjugate molecules. The candidate will focus on all aspects of development spanning conceptualization, experimentation, data analysis, presentation, and strategic planning.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Nucleic acid manipulation, modification, and analytic approaches&lt;/li&gt;
&lt;li&gt;Viral and non-viral nucleic acid formulation and delivery&lt;/li&gt;
&lt;li&gt;Quantitative analysis of biological molecules&lt;/li&gt;
&lt;li&gt;Critical data analysis, attention to detail, and troubleshooting abilities&lt;/li&gt;
&lt;li&gt;Written and oral presentation of results&lt;/li&gt;
&lt;li&gt;Manage and oversee CROs, providing technical expertise and direction on production and characterization activities&lt;/li&gt;
&lt;li&gt;Generate and support intellectual property generation for core projects&lt;/li&gt;
&lt;li&gt;Mentor and train research associates as needed&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Minimum Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Ph.D. in Molecular Biology, Biochemistry, Bioengineering or related discipline&lt;/li&gt;
&lt;li&gt;Deep knowledge and understanding of RNA biology. Proficient in experimental design, assay execution, troubleshooting, data analysis, and data interpretation&lt;/li&gt;
&lt;li&gt;Skilled in assay development and optimization of nucleic acid production, purification and biophysical characterization&lt;/li&gt;
&lt;li&gt;Execution focused, team oriented, and highly motivated&lt;/li&gt;
&lt;li&gt;Experience with the following techniques is highly preferred: RT-qPCR, RNA-seq, cloning, cell culture, immunohistochemistry, ELISA, ChIP, EMSA, FISH, Northern and Western blotting&lt;/li&gt;
&lt;/ul&gt;

FL92/93: (Sr) Scientist – RNA Biology

&lt;p&gt;&lt;strong&gt;What if…&lt;/strong&gt;you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies to transform human health and sustainability?&lt;/p&gt;
&lt;p&gt;Flagship Pioneering&#x27;s venture creation engine has conceived and created companies such as Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), and Editas Medicines (NASDAQ: EDIT). Since its launch in 2000, Flagship has applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $212 billion in aggregate value. To date, Flagship has deployed over $2.5 billion in capital toward the founding and growth of its pioneering companies alongside more than $19 billion of follow-on investments from other institutions. In 2021, Flagship Pioneering was ranked 12&lt;sup&gt;th&lt;/sup&gt;globally on &lt;em&gt;Fortune&lt;/em&gt;’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;The Company:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;FL85 is a Flagship backed, privately held biotechnology company on a mission to transform the current approach to information molecule therapeutics to unlock their full therapeutic potential. In recent years, we have begun to experience the power of information molecules in treating historically undruggable diseases and in designing therapies with unprecedented turnaround times. FL85’s platform integrates nanoparticle development with world-class informatics technologies and a novel pipeline of experimentation and discovery to drive a new generation of highly effective, therapeutically relevant information molecule therapies. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us!&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;FL85 is seeking a proactive and self-motivated Bioinformatics Scientist (NGS) to develop computational pipelines to enable analysis of next-generation sequencing applications utilizing nucleic acids barcoding technologies. She/he will work with experimental scientists to select key technologies, and devise sequencing prep protocols. The successful candidate will be comfortable iterating rapidly in development phase, while building robust and reliable pipelines in production. This individual will join a world-class, dynamic, and highly collaborative team that is driving a novel platform for delivery of information molecule therapeutics.&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Design and implement custom NGS processing pipelines, statistical models, and analysis methods for high-throughput multiplex sequencing.&lt;/li&gt;
&lt;li&gt;Act as internal expert and thought leader for NGS computational methodology.&lt;/li&gt;
&lt;li&gt;Interface NGS pipelines with in-house data platform and computational cluster via programmatic APIs and web apps.&lt;/li&gt;
&lt;li&gt;Process and analyze genomic and transcriptomic data.&lt;/li&gt;
&lt;li&gt;Develop production-quality code and scalable, reproducible, shared workflows in a team setting.&lt;/li&gt;
&lt;li&gt;Present progress from scientific work in regular research meetings.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;MS with 3+ years industry experience or PhD in Computational Biology, Computer Science or a related field.&lt;/li&gt;
&lt;li&gt;Demonstrated experience applying NGS computational techniques to a variety of biological applications.&lt;/li&gt;
&lt;li&gt;Experience developing, debugging, and applying custom software for processing raw reads and alignments.&lt;/li&gt;
&lt;li&gt;Proficiency in Python and experience analyzing data with Numpy/Scipy, R, or similar.&lt;/li&gt;
&lt;li&gt;Deep expertise in managing Linux environments using Docker, as well as package management using conda, pip, apt/yum or other package management tools.&lt;/li&gt;
&lt;li&gt;Experience deploying robust, automated workflows using workflow management tools such as Prefect, Luigi, Cromwell, or similar, and compute cluster infrastructures such as AWS ECS, Kubernetes, LSF, or similar.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Preferred Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Experience designing and optimizing NGS experiments, in the biotech industry.&lt;/li&gt;
&lt;li&gt;Demonstrated experience developing software in a team setting.&lt;/li&gt;
&lt;li&gt;Experience with optimizing performant code.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;Flagship Pioneering and our ecosystem companies are&amp;nbsp;&lt;strong&gt;committed to equal employment opportunity &lt;/strong&gt;regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;&lt;em&gt;Recruitment &amp;amp; Staffing Agencies&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/p&gt;

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