&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;dhkj5-0-0&quot;&gt;
&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;
&lt;p&gt;&lt;strong&gt;About Alltrna&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Flagship Pioneering has conceived of and created companies such as Moderna Therapeutics (NASDAQ: MRNA), Editas Medicine (NASDAQ: EDIT), Omega Therapeutics (NASDAQ: OMGA), Seres Therapeutics (NASDAQ: MCRB), and Indigo Agriculture. Since its launch in 2000, Flagship has applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures. In 2021, Flagship Pioneering was ranked 12th globally on Fortune’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies.&lt;/p&gt;
&lt;p&gt;Alltrna is the world’s first tRNA platform company to decipher tRNA biology and pioneer tRNA therapeutics to treat thousands of diseases. Alltrna unlocks tRNA biology to correct disease. The company&#x27;s platform incorporates AI/ML tools to learn the tRNA language and deliver diverse programmable molecules with broad therapeutic potential. Alltrna has an unprecedented opportunity to advance a single tRNA medicine to unify treatment across a wide range of diseases with the same underlying genetic mutation. Alltrna was founded in 2018 by Flagship Pioneering. For more info, visit&amp;nbsp;&lt;a href=&quot;https://c212.net/c/link/?t=0&amp;amp;l=en&amp;amp;o=3349115-1&amp;amp;h=1969233582&amp;amp;u=https%3A%2F%2Fwww.alltrna.com%2F&amp;amp;a=www.alltrna.com&quot;&gt;www.alltrna.com&lt;/a&gt;.&lt;/p&gt;
&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;
&lt;p&gt;&lt;strong&gt;About The Role&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Alltrna is seeking a highly motivated and creative Lab Automation Senior Research Associate/Scientist to join us in support of our platform discovery engine for tRNA therapeutics.&amp;nbsp; In this role you will use deep technical understanding of cell biology and lab automation to apply high-throughput techniques for hit to lead activities aiding in the discovery of groundbreaking tRNA therapeutics.&amp;nbsp; You will use cutting-edge biology and the latest lab technology as you work to design, implement, and analyze automated and high-throughput cellular and biochemical experiments.&amp;nbsp; The ideal candidate will have a strong background in the deployment and programming of lab automation as well as the execution of high-throughput cellular screening assays.&amp;nbsp; They will have utilized equipment such as the Biomek I7 and Bravo, scheduling software such as Thermo Momentum and various types of bulk dispensers and microplate washers.&amp;nbsp; This expertise will be applied to the optimization of screens using physiologically relevant cell systems, luminescent reporters, high-content imaging, and flow cytometry to generate data at scale.&amp;nbsp;&lt;/p&gt;
&lt;p&gt;The position will be closely aligned with the Computational Molecular Biology, Pharmacology &amp;amp; DMPK, and Bioinformatics teams.&amp;nbsp; As such, the candidate should be able to work effectively in a multi-disciplinary environment and have excellent written and verbal communication skills with a capacity for innovation and creativity to achieve company goals.&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;&amp;nbsp;&lt;/strong&gt;&lt;strong&gt;Core Responsibilities&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Scale up cell-based assays in 96 and 384 well formats to high-throughput by developing and executing compatible automated workflows that insure consistency with sample and data integrity. &amp;nbsp;&lt;/li&gt;
&lt;li&gt;Program liquid handling methods, make use of bulk dispensers, and execute screening campaigns.&lt;/li&gt;
&lt;li&gt;Perform analysis of large data sets from multiplate screens and have familiarity analyzing multiparametric data from flow cytometry and high-content image processing.&lt;/li&gt;
&lt;li&gt;Scale up cell culture and manage key cell line stocks.&lt;/li&gt;
&lt;li&gt;Manage tRNA screening library samples in a LIMS tracible format and distribute these reagents to key internal collaborators.&lt;/li&gt;
&lt;li&gt;Develop and deploy LIMS tools in collaboration with the bioinformatics team to support assay automation, sample management, tracking and data delivery to the ELN system.&lt;/li&gt;
&lt;li&gt;Explore new areas of lab technology with a forward-looking mindset to drive innovation as a technology expert. Train users on new methods and protocols.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Knowledge of Design of Experiments (DoE) models to accelerate assay development.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;&amp;nbsp;&lt;/strong&gt;&lt;strong&gt;Required Qualifications&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;BS in biology, biotechnology, engineering, or related field with 5-6 years of relevant experience in industry; or MS in related field with 3-4 years of relevant experience in industry. PhD with 1+ years of relevant experience please also apply.&lt;/li&gt;
&lt;li&gt;Outstanding organizational skills and ability to contribute in a fast paced environment.&lt;/li&gt;
&lt;li&gt;Excellent at troubleshooting and problem solving and independently motivated to accomplish goals.&lt;/li&gt;
&lt;li&gt;Excellent written and oral communication skills and the ability to work in a team environment.&lt;/li&gt;
&lt;li&gt;Expert knowledge in data analysis software, such Excel, GraphPad Prism, JMP, Spotfire or Tableau and FlowJo.&lt;/li&gt;
&lt;li&gt;Experience with tissue culture and cell-based assays including reporter gene assays.&lt;/li&gt;
&lt;li&gt;Familiarity working with RNA and performing molecular biology techniques.&lt;/li&gt;
&lt;li&gt;Willingness to share expertise, learn, and develop new techniques.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;&amp;nbsp;&lt;/strong&gt;&lt;strong&gt;Technical skills&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Hands-on experience with high-throughput liquid handling system operation, programming, troubleshooting, and maintenance.&lt;/li&gt;
&lt;li&gt;Experience with liquid handlers such as Beckman Coulter Biomek i7, Agilent Bravo, Integra Vaiflow&lt;/li&gt;
&lt;li&gt;Experience with bulk dispensers such as Thermo Combi and Formulatrix Mantis.&lt;/li&gt;
&lt;li&gt;Capability with multi-mode plate readers such as Thermo Varioskan and PerkinElmer Envision.&lt;/li&gt;
&lt;li&gt;Familiarity with flow-cytometers such as NovoCyte Quanteon and fluorescent imaging systems such as Sartorius Incucyte and BioTek Lionheart.&lt;/li&gt;
&lt;li&gt;Familiarity with automated electrophoresis such as Agilent TapeStation, Oligo Pro and ProteinSimple JESS.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;What We’ll Offer You&lt;/strong&gt;&amp;nbsp;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Comprehensive, competitive healthcare and dental coverage through Blue Cross Blue Shield, vision coverage through VSP, family leave, paid time off, 401k retirement plan, disability and life insurance, and fully covered parking/commuter benefits.&lt;/li&gt;
&lt;li&gt;A dynamic early-stage work environment and highly interdisciplinary, talented, and collaborative team.&lt;/li&gt;
&lt;li&gt;Participation in an unprecedented opportunity to advance a single tRNA medicine to restore disrupted protein production, regardless of target, for thousands of diseases with the same underlying genetic mutation.&lt;/li&gt;
&lt;li&gt;Professional growth opportunities through mentoring, training, immersion in cross-functional projects, and opportunities to learn and try new things.&lt;/li&gt;
&lt;li&gt;Be part of the team that writes the playbook for developing tRNA molecules and you will be critical not only in ensuring that we can understand how our formulations perform in living systems but also in defining how we manufacture for our clinical programs.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;&amp;nbsp;&lt;/strong&gt;&lt;strong&gt;Our Core Values&lt;/strong&gt;&amp;nbsp;&lt;/p&gt;
&lt;ol&gt;
&lt;li&gt;&lt;strong&gt;PATIENTS DESERVE BETTER&lt;em&gt;.&lt;/em&gt;&lt;/strong&gt; We are transforming medicine, boldly building a new future for patients.&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;CURIOSITY SPARKS DISCOVERY&lt;em&gt;.&lt;/em&gt;&lt;/strong&gt; We ardently explore the unknown, catalyzing new scientific breakthroughs.&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;COURAGE PROPELS US FORWARD.&lt;/strong&gt; We take thoughtful risks without fear of failure, growing with each experience.&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;OUR PURPOSE FUELS US&lt;/strong&gt;. We each lead and work with focus and passion to design groundbreaking tRNA medicines.&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;WE ARE ONE TEAM&lt;em&gt;.&lt;/em&gt;&lt;/strong&gt; We are united on trust and collaboration, embracing all voices and experiences.&lt;/li&gt;
&lt;/ol&gt;
&lt;p&gt;&lt;strong&gt;WE GIVE IT OUR ALL, EVERYDAY, FOR PATIENTS EVERYWHERE. WE ARE ALLTRNA.&lt;/strong&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt; &amp;nbsp;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;&amp;nbsp;&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;Flagship Pioneering and our ecosystem companies are &lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;&amp;nbsp;&lt;/div&gt;
&lt;/div&gt;
&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

Senior Research Associate/ Scientist I, High-Throughput Biology and Lab Automation

&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;dhkj5-0-0&quot;&gt;
&lt;p&gt;&lt;strong&gt;Company Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;What if…&lt;/strong&gt; you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?&lt;/p&gt;
&lt;p&gt;Metaphore Biotechnologies is an early-stage biotechnology company with an ambitious and exciting mission: to reimagine drug discovery and vaccine design. The company is developing a first-in-class platform for the intelligent design of molecular mimicry. Our platform integrates massively parallel assays with machine-learning-guided protein engineering to navigate the combinatorial space of molecular interactions and design protein-protein interfaces with exquisite precision.&lt;/p&gt;
&lt;p&gt;Metaphore Biotechnologies is a product of Flagship Pioneering&#x27;s venture creation engine, which has also given rise to companies such as Moderna Therapeutics (NASDAQ: MRNA), Editas Medicine (NASDAQ: EDIT), Omega Therapeutics (NASDAQ: OMGA), Seres Therapeutics (NASDAQ: MCRB), and Indigo Agriculture. Since its launch in 2000, Flagship has applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures. In 2021, Flagship Pioneering was ranked 12th globally on Fortune’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary&lt;/strong&gt;:&lt;/p&gt;
&lt;p&gt;We are seeking a motivated Computational Immunologist to join our rapidly growing team. The successful candidate will conduct immune repertoire analysis with highly parallel assay data and computational modeling to support the discovery, engineering, and evaluation of novel therapeutic antibodies and vaccines. They will play a key role in our discovery through translational efforts, formulating and executing on a science &amp;amp; technology strategy that will allow the company to deliver against its goals.&amp;nbsp;&lt;/p&gt;
&lt;p&gt;This position requires a strong foundation in the biology of the adaptive immune system and computational immune repertoire analysis, including interrogation of large in vitro and in vivo experiments to characterize determinants of immune receptor specificity and the response to candidate therapeutics and vaccination strategies. &amp;nbsp;The candidate will work closely with experimental and computational scientists to interpret results and design experiments.&amp;nbsp; This individual will join an interdisciplinary and collaborative team at the interface of computational immunology, functional genomics, and next-generation antibody design; they should be comfortable communicating and working with diverse backgrounds in a fast-paced startup environment.&lt;/p&gt;
&lt;p&gt;The candidate will have an extraordinary opportunity to be part of the Flagship ecosystem of companies providing unique networking benefits through regular meetups, collaboration, and an environment of development and discussion around new ideas shaping the fields of computational biology and ML/AI.&lt;/p&gt;
&lt;p&gt;In the interest of fostering collaboration, the candidate is expected to work on-site at our Kendall Square, Cambridge, MA location.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Explore, design, and implement bioinformatic algorithms for immune repertoire analysis&lt;/li&gt;
&lt;li&gt;Assist the design of screening libraries and build NGS analysis pipelines for hit identification&lt;/li&gt;
&lt;li&gt;Formulate hypotheses, aid experimental design and perform analyses to evaluate novel immunization strategies&lt;/li&gt;
&lt;li&gt;Collaborate with team members to interpret immunogenicity&lt;/li&gt;
&lt;li&gt;Leverage internal and external datasets to further develop our ML-guided protein-interface engineering platform&lt;/li&gt;
&lt;li&gt;Collaborate with engineers, computation scientists, and experimentalists to execute on company goals&lt;/li&gt;
&lt;li&gt;Communicate insights and conclusions to colleagues in the scientific and leadership teams&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Basic Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Ph.D. plus 2-5 years of experience in computational biology, bioinformatics, immunology, or a related field&lt;/li&gt;
&lt;li&gt;Strong skills in immune repertoire analysis, particularly as pertains to understanding antibody maturation and the repertoire response to vaccination&lt;/li&gt;
&lt;li&gt;Experience with NGS data pipelines and analysis&lt;/li&gt;
&lt;li&gt;Excellent understanding of statistics&lt;/li&gt;
&lt;li&gt;Strong programming skills in Python (preferably) or R and knowledge of software best practices&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Preferred Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Experience with protein engineering or vaccine development&lt;/li&gt;
&lt;li&gt;Experience with machine learning, especially in the context of biomolecules&lt;/li&gt;
&lt;li&gt;Experience with publicly available data sources such as IMGT, OAS or ImmPort&lt;/li&gt;
&lt;li&gt;Experience with cloud and/or distributed computing&lt;/li&gt;
&lt;li&gt;Experience with single cell immune profiling&lt;/li&gt;
&lt;li&gt;Laboratory experience in molecular biology or immunology&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Values and Behaviors:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Flagship is an experiment in institutional, entrepreneurial, and innovation practiced in the context of a small company with an insurgent mindset. We are seeking individuals with an entrepreneurial spirit, strong communication skills, and comfort in working in and contributing to a dynamic and cross-functional team environment. The level of the role will be commensurate with the education and years of experience of the identified candidates.&lt;/p&gt;
&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;Flagship Pioneering and our ecosystem companies are &lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;&amp;nbsp;&lt;/div&gt;
&lt;/div&gt;
&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;&amp;nbsp;&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

Scientist, Computational Biology

&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;dhkj5-0-0&quot;&gt;
&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;
&lt;p&gt;&lt;strong&gt;What if…&lt;/strong&gt;you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?&lt;/p&gt;
&lt;p&gt;Radial Therapeutics, Inc. is a privately held, well-funded, early-stage biotechnology company leveraging novel insights in RNA biology. Radial Therapeutics’s proprietary platform identifies novel disease targets and develops new therapeutic modalities targeting RNA, providing new strategies to treat or cure a range of diseases including rare genetic diseases, neurological diseases, and cancers.&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Position summary&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;We are seeking a Scientist I in Computational Biology to join a multidisciplinary team dedicated to finding novel avenues to drug RNAs using small molecules. Applying rigorous, quantitative and statistical methods, you will pioneer the development of sophisticated computational models to answer key biological questions for uncovering novel RNA-small molecule interactions. In particular, your advanced knowledge of comparative genomics and computational modeling together with broad expertise across RNA biology, data engineering and bioinformatics data processing will allow us to crack the code to drug RNAs with small molecules. Operationally, this position will require close collaboration with experimental biologists and AI scientists to generate and test hypotheses in the field of RNA-small molecule interactions.&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Responsibilities&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Translate biological questions into computational problems&lt;/li&gt;
&lt;li&gt;Use publicly available data, proprietary data, comparative sequence analysis and other evolutionary information to build computational models aiming to uncover novel RNA-small molecule interactions&lt;/li&gt;
&lt;li&gt;Actively participate in designing experimental approaches to generate relevant data as well as to validate computational insights&lt;/li&gt;
&lt;li&gt;Develop computational frameworks to systematically characterize results from machine learning models from a biological perspective and provide feedback on improving the models&lt;/li&gt;
&lt;li&gt;Contribute new ideas, strategies and approaches that further the company’s goals&lt;/li&gt;
&lt;li&gt;Create concise data visualizations and communicate complex results to an interdisciplinary audience&lt;/li&gt;
&lt;/ul&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Requirements&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;PhD in computational sciences (e.g. computational biology, computer science or mathematics) with applications in biology, or PhD in biological sciences with strong computational expertise&lt;/li&gt;
&lt;li&gt;1+ years industry or postdoctoral experience is preferred&lt;/li&gt;
&lt;li&gt;5+ years experience in processing, analyzing and modeling large biological datasets (e.g. genomic, transcriptomic) to answer key biological questions&lt;/li&gt;
&lt;li&gt;Deep expertise in comparative genomics and comparative sequence analysis, including whole genome alignments (e.g. Cactus), synteny analysis (e.g. SynChro), annotation (e.g. InterProScan, KAAS) and phylogenetics, both using maximum likelihood (e.g. SeaView) and Bayesian models (e.g. MrBayes)&lt;/li&gt;
&lt;li&gt;Hands-on experience with a variety of DNA/RNA/protein tools for sequence searches and consensus determination, including alignment-based (e.g. BLAST, MUSCLE, Mafft) and Markov/covariance-based (e.g. nhmmer, Infernal, CMfinder)&lt;/li&gt;
&lt;li&gt;Experience predicting and analyzing 2D RNA structures, including using chemical probing data (e.g. DMSMaPseq, SHAPEseq) to inform RNA structures&lt;/li&gt;
&lt;li&gt;Advanced knowledge of statistics (frequentist and Bayesian) for analyzing complex, multidimensional data&lt;/li&gt;
&lt;li&gt;Strong programming skills in Python and scientific libraries such as pandas, numpy, scipy, matplotlib, biopython. Proficiency in other programming languages such as Perl, C/C++ and java is a plus.&lt;/li&gt;
&lt;li&gt;Experience developing data processing, engineering and statistical analysis workflows using AWS services such as S3, EC2, ECS, AWS Batch, NextFlow&lt;/li&gt;
&lt;li&gt;Foundational knowledge of machine learning and small molecule therapeutics is a plus&lt;/li&gt;
&lt;/ul&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Location: &lt;/strong&gt;Cambridge, MA&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;More&amp;nbsp;About Flagship Pioneering&lt;/strong&gt;&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;Flagship Pioneering conceives, creates, resources, and develops first-in-category life science platform companies to transform human health and sustainability. Since its launch in 2000, the firm has, through its Flagship Labs unit, applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $100 billion in aggregate value. To date, Flagship has deployed over $3.1 billion in capital toward the founding and growth of its pioneering companies alongside more than $19 billion of follow-on investments from other institutions. The current Flagship ecosystem comprises&amp;nbsp; transformative companies, including&amp;nbsp; Moderna&amp;nbsp;(NASDAQ: MRNA), Sana&amp;nbsp;Biotechnology (NASDAQ:&amp;nbsp;SANA),&amp;nbsp;Seres&amp;nbsp;Therapeutics (NASDAQ: MCRB), Axcella&amp;nbsp;Health (NASDAQ: AXLA), Denali&amp;nbsp;Therapeutics (NASDAQ: DNLI),&amp;nbsp;Foghorn&amp;nbsp;Therapeutics (NASDAQ: FHTX),&amp;nbsp;Indigo&amp;nbsp;Ag, Generate Biomedicines, Tessera Tx, and others.&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;Flagship Pioneering and our ecosystem companies are&amp;nbsp;&lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&amp;nbsp;We believe pioneering is best done by teams, and that it is a process that can be taught, learned, and replicated.&amp;nbsp;&amp;nbsp;Learn more about&amp;nbsp;our&amp;nbsp;&lt;a href=&quot;https://www.flagshippioneering.com/process&quot;&gt;Company Creation Model&lt;/a&gt;.&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;Can Breakthrough Innovations Be Made Systematically&lt;a href=&quot;https://www.flagshippioneering.com/stories/can-innovations-be-made-systematically-a-conversation-with-noubar-afeyan&quot;&gt;? A Conversation With Noubar Afeyan&lt;/a&gt;, Flagship Pioneering’s CEO.&amp;nbsp;&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;Flagship Pioneering&amp;nbsp;and&amp;nbsp;our ecosystem companies are committed to&amp;nbsp;&lt;strong&gt;equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;&lt;em&gt;Recruitment &amp;amp; Staffing Agencies:&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;&amp;nbsp; Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates.&amp;nbsp; The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team.&amp;nbsp;&amp;nbsp; Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&amp;nbsp;&lt;/p&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

Scientist I, Computational Biology 

&lt;div class=&quot;content-intro&quot;&gt;&lt;p&gt;Vizgen, Inc. – Cambridge, MA&lt;/p&gt;
&lt;p&gt;&lt;br&gt;Vizgen is a rapidly growing company developing the next generation of spatially resolved genomic profiling tools that enable researchers to gain new insight into the biological systems that underlie human health and disease. The company&#x27;s groundbreaking MERFISH spatial transcriptomics technology images RNA molecules with high accuracy and unrivaled detection efficiency at subcellular resolution. MERFISH provides transformative insight into a wide range of tissue-scale basic research and translational medicine in oncology, immunology, neuroscience, infectious disease, developmental biology, and regenerative medicine. For more information, go to www.vizgen.com&lt;/p&gt;&lt;/div&gt;&lt;p&gt;&lt;span style=&quot;font-size: 10pt; font-family: helvetica, arial, sans-serif;&quot;&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 10pt; font-family: helvetica, arial, sans-serif;&quot;&gt;We are looking for a senior data engineer to use their analytical, statistical, and programming skills to collect, curate, analyze, and present data from Vizgen’s image based spatial transcriptomics platform and research and development projects. Your primary focus will be integrating data from various sources, identifying, calculating, and refining key performance statistics, and establishing informative dashboards to present real-time results and informative analysis to stakeholders across the organization. The efforts will be critical to ensure that our R&amp;amp;D efforts are continuing to improve our spatial transcriptomic data quality and identify weaknesses or sources of variation to investigate farther and enable Vizgen’s technical support team to effectively support our install base.&amp;nbsp; You will be working alongside computational biologists, engineers, and scientists. Therefore, a commitment to collaborative problem solving and the curation of accurate, robust and informative data sources and analysis is essential.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;&lt;strong&gt;Responsibilities:&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;Curate and analyze Vizgen experimental and MERSCOPE data, identifying data quality variations arising from changes in protocols, reagents, or other variables.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;Work across the full-spectrum of data activities, from data ETL and cataloging to building models and statistics to provide deeper insight into the data and presenting the results in accessible dashboards&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;Build and implement data analysis pipelines to transform data into accessible and presentable formats.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;Collaborate with Vizgen’s reagent research and development teams to evaluate trends in data quality or data quality consequences from R&amp;amp;D experiments.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;Identify and implement key data quality performance metrics&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;Communicate instrument quality trends with Vizgen’s commercial and technical support teams, building automated alarms for critical issues to help the technical support team stay one step ahead of customer concerns&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;Continually improve speed and efficiency of big data analysis&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;Collaborate with the software and hardware engineering teams to team to identify additional metrics that could be logged to provide a more complete picture of instrument performance.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Requirements and Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;Masters or Ph.D. in CS/Data Science/Mathematics/Statistics/Bioinformatics or related quantitative discipline + at least 4 years of industry experience in a highly quantitative field&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;A technical mindset with great attention to detail with deep data, math and statistical analysis skills&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;Expertise in Python (preferred) or other programming language, particularly data science libraries&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;Familiarity with time series analysis methods&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;Familiarity with data management tools to curate and efficiently access large datasets&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;Excellent communication skills to translate complex analysis into insightful visuals for a broad audience with varying technical background.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;Extensive experience with AWS and GCP&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;Knowledge of dashboarding tools, such as Tableau, Power BI, Plotly, etc.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;Able to efficiently determine best methods for accomplishing work and achieving deliverables&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;Proficient understanding of code versioning tools, such as git&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;h2&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;&lt;strong&gt;Preferred Skills:&lt;/strong&gt;&lt;/span&gt;&lt;/h2&gt;
&lt;ul&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;Hands-on experience with scientific instrumentation&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;Experience with biological or instrumentation data&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 10pt;&quot;&gt;Experience developing algorithms for embedd&lt;/span&gt;ed systems (FPGA/GPU) strongly preferred&lt;/li&gt;
&lt;/ul&gt;&lt;div class=&quot;content-conclusion&quot;&gt;&lt;p&gt;If you aren&#x27;t sure you meet every requirement but are excited about what you read here, please consider applying! We believe diversity drives innovation.&amp;nbsp; Above all, we&#x27;re looking for the right person with skills and talent to grow the company together all while enriching your professional and scientific experience.&lt;/p&gt;
&lt;p&gt;We offer a competitive salary, meaningful stock ownership, 401K, health benefits, a great work environment and the opportunity to enter a high-growth startup company. We are recruiting candidates who have demonstrated leadership and excellence throughout their careers and are excited by the prospect of tackling challenging technical problems.&lt;/p&gt;
&lt;p&gt;&lt;em&gt;This position may be subject to pre-employment checks, including driving history check, drug screening and a background check for any convictions directly related to its duties and responsibilities. All pre-employment checks will comply with all applicable federal, state, and local laws.&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;WE ARE AN EQUAL OPPORTUNITY/AFFIRMATIVE ACTION EMPLOYER&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Vizgen affords equal employment opportunity to all qualified persons regardless of race, color, religious creed, national origin, age, military status, sexual orientation, disability, genetic information, gender identity, gender expression or gender unless based upon a bona fide occupational qualification.&lt;/p&gt;&lt;/div&gt;

Senior Data Engineer

&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;dhkj5-0-0&quot;&gt;
&lt;p&gt;&lt;strong&gt;What if…&lt;/strong&gt;&amp;nbsp;you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?&lt;/p&gt;
&lt;p&gt;Metaphore Biotechnologies is an early-stage biotechnology company with an ambitious and exciting mission: to reimagine drug discovery and vaccine design. The company is developing a first-in-class platform for the intelligent design of molecular mimicry. Our platform integrates massively parallel assays with machine-learning-guided protein engineering to navigate the combinatorial space of molecular interactions and design protein-protein interfaces with exquisite precision.&lt;/p&gt;
&lt;p&gt;Metaphore Biotechnologies is a product of Flagship Pioneering&#x27;s venture creation engine, which has also given rise to companies such as Moderna Therapeutics (NASDAQ: MRNA), Editas Medicine (NASDAQ: EDIT), Omega Therapeutics (NASDAQ: OMGA), Seres Therapeutics (NASDAQ: MCRB), and Indigo Agriculture. Since its launch in 2000, Flagship has applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures. In 2021, Flagship Pioneering was ranked 12th globally on Fortune’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Metaphore Biotechnologies is seeking an enthusiastic Senior Scientist to join our Computational Biology team and accelerate the design of protein-protein interfaces.&amp;nbsp; In this role, you will collaborate closely with members of the Computational Biology and Protein Engineering teams to advance our use of next-generation sequencing-based mutational assays to characterize and engineer molecular interactions.&amp;nbsp; Your scientific-rigor and creativity will advance our platform, unlocking the potential of molecular mimicry for therapeutic development.&amp;nbsp; The ideal candidate will bring experience in mutational screening, bioinformatic pipelines design and analysis, and experience implementing robust data standards.&amp;nbsp; This individual will have the opportunity to join a dynamic interdisciplinary team working at the interface of computational biology, protein engineering, functional genomics and machine learning.&lt;/p&gt;
&lt;p&gt;The candidate will also have an extraordinary opportunity to be part of the Flagship ecosystem of companies, providing unique networking benefits through regular meetups, collaboration, and an environment of development and discussion around new ideas shaping the fields of computational biology and ML/AI.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Provide scientific and technical expertise in the analysis and interpretation of NGS-based mutational screens.&lt;/li&gt;
&lt;li&gt;Contribute to the continuous development of scientifically rigorous next-generation sequencing (NGS) pipelines.&lt;/li&gt;
&lt;li&gt;Develop and implement computational frameworks to derive biological insights from data, such as mapping key residues for molecular interactions and estimating interaction kinetics.&lt;/li&gt;
&lt;li&gt;Collaborate on experimental design to establish and maintain high data quality standards and confidence in results.&lt;/li&gt;
&lt;li&gt;Leverage internal and external datasets to aid in interpretation and further develop our ML-guided protein engineering platform.&lt;/li&gt;
&lt;li&gt;Collaborate with computational and experimental scientists and engineers to execute on company goals.&lt;/li&gt;
&lt;li&gt;Communicate insights and conclusions to scientific colleagues and the leadership team.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;PhD or equivalent, plus 3+ years of experience in computational biology, bioinformatics, or a related field.&lt;/li&gt;
&lt;li&gt;Experience developing robust quantitative NGS-based pipelines in a cloud platform.&amp;nbsp; Familiarity with AWS, docker and snakemake is a plus.&lt;/li&gt;
&lt;li&gt;Experience with screening or highly parallel protein engineering workflows is highly desired.&lt;/li&gt;
&lt;li&gt;Prior experience in automated noise thresholding is a plus.&lt;/li&gt;
&lt;li&gt;Very strong programming skills in python and knowledge of software development best practices.&lt;/li&gt;
&lt;li&gt;Excellent communication skills and capable of clearly conveying technical information.&lt;/li&gt;
&lt;li&gt;Experience collaborating with wet lab scientists to jointly execute on goals.&lt;/li&gt;
&lt;li&gt;Strong organization and problem-solving skills.&lt;/li&gt;
&lt;li&gt;Experience with machine learning of biomolecules is a plus.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;Flagship Pioneering and our ecosystem companies are&amp;nbsp;&lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt;&amp;nbsp;regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;&lt;em&gt;Recruitment &amp;amp; Staffing Agencies&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/p&gt;
&lt;/div&gt;

Senior Scientist, Computational Biology

&lt;div class=&quot;content-intro&quot;&gt;&lt;p class=&quot;p1&quot;&gt;&lt;strong&gt;We make healthy cells invisible to targeted therapies&lt;/strong&gt;&lt;/p&gt;
&lt;p class=&quot;p1&quot;&gt;Targeted therapies work by attacking cells that express particular proteins on their surface. Unfortunately, both diseased and healthy cells often express the same proteins, resulting in collateral damage to healthy cells.&lt;/p&gt;
&lt;p class=&quot;p1&quot;&gt;At Vor Bio, we engineer hematopoietic stem cells (HSCs) to lack a biologically redundant target protein, then transplant these cells into the patient.&lt;/p&gt;
&lt;p class=&quot;p1&quot;&gt;These eHSCs give rise to generations of new healthy blood cells that are effectively invisible to targeted therapies. Diseased cells displaying the target protein and are then vulnerable to attack. This process potentially broadens the therapeutic window and improves the utility of complementary targeted therapies.&lt;/p&gt;
&lt;p class=&quot;p1&quot;&gt;&lt;strong&gt;What we value in our fellow Voracians&lt;/strong&gt;&lt;/p&gt;
&lt;p class=&quot;p1&quot;&gt;&lt;strong&gt;Passion:&lt;/strong&gt;&amp;nbsp;Enthusiastically driving our science toward innovative medicines&lt;/p&gt;
&lt;p class=&quot;p1&quot;&gt;&lt;strong&gt;Fellowship:&lt;/strong&gt;&amp;nbsp;Fostering genuine bonds of collaboration and mentorship&lt;/p&gt;
&lt;p class=&quot;p1&quot;&gt;&lt;strong&gt;Humility:&lt;/strong&gt;&amp;nbsp;Acting selflessly by putting the collective mission first&lt;/p&gt;
&lt;p class=&quot;p1&quot;&gt;&amp;nbsp;&lt;/p&gt;&lt;/div&gt;&lt;p&gt;&lt;strong&gt;Who we are looking for:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Vor Bio is seeking a Computational Biologist to join our growing quantitative biology team. The successful candidate will work onsite with a group of multi-disciplinary scientists and apply computational approaches and data sciences expertise to support the development of innovative cell and gene therapy products.&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key areas of responsibilities&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Perform analyses of cutting-edge genome editing therapeutics data and partner with research and development teams to support genome engineering programs.&lt;/li&gt;
&lt;li&gt;Develop, maintain, and standardize bioinformatics pipelines using workflow management tools and scale the analysis with AWS cloud&lt;/li&gt;
&lt;li&gt;Contribute to all aspects of target discovery and validation including but not limited to strategy development and planning, tool development and execution of individual projects&lt;/li&gt;
&lt;li&gt;Work with regulatory authorities to standardize the bioinformatics workflow inhouse and prepare scientific study reports for regulatory submission&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Ph.D. and 1+ years of academic/industry experience in Bioinformatics, Computational Biology, Genomics, or other related fields&lt;/li&gt;
&lt;li&gt;Fluent in programing languages Python, Bash scripting, and R&lt;/li&gt;
&lt;li&gt;Demonstrated experience in developing bioinformatics tools/pipelines is required&lt;/li&gt;
&lt;li&gt;Experience working in the cloud environment (AWS) and Docker-based deployment&lt;/li&gt;
&lt;li&gt;Experience analyzing gene editing NGS assays for on-target/off-target prediction and assessment is preferred&lt;/li&gt;
&lt;li&gt;Excellent verbal and written communication skills&lt;/li&gt;
&lt;li&gt;Enjoy working in a multi-disciplinary team to achieve project goals&lt;/li&gt;
&lt;li&gt;Must be able to work in the Vor Bio office regularly&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;&lt;div class=&quot;content-conclusion&quot;&gt;&lt;p&gt;By becoming a team member here at Vor, you’ll have access to competitive health, dental, and vision coverage, as well as life insurance, and short term and long-term disability insurance. We value work life balance, you&#x27;ll benefit from discretionary time off, parental leave, and an excellent 401(k) package. We also offer a generous transportation stipend to commute as you wish. We are conveniently located in &lt;br&gt;Cambridge with easy access to public transportation and ample parking.&lt;/p&gt;
&lt;p class=&quot;p1&quot;&gt;As an equal opportunity employer, we at Vor Bio know that diversity inspires innovation, inclusiveness, and creativity. We invite you to come as you are. All applicants will be considered for employment agnostic to race, age, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.&lt;/p&gt;
&lt;p&gt;In an effort to protect our coworkers and communities from COVID-19, where permitted by law Vor Biopharma Inc. requires all employees to be fully vaccinated against COVID-19 and up to date with their vaccination unless they receive an approved reasonable accommodation for medical or religious reasons.&lt;/p&gt;
&lt;p&gt;Please visit our website at https://www.vorbio.com/ for more information.&lt;/p&gt;&lt;/div&gt;

Computational Biologist

&lt;div class=&quot;content-intro&quot;&gt;&lt;p&gt;Vizgen, Inc. – Cambridge, MA&lt;/p&gt;
&lt;p&gt;&lt;br&gt;Vizgen is a rapidly growing company developing the next generation of spatially resolved genomic profiling tools that enable researchers to gain new insight into the biological systems that underlie human health and disease. The company&#x27;s groundbreaking MERFISH spatial transcriptomics technology images RNA molecules with high accuracy and unrivaled detection efficiency at subcellular resolution. MERFISH provides transformative insight into a wide range of tissue-scale basic research and translational medicine in oncology, immunology, neuroscience, infectious disease, developmental biology, and regenerative medicine. For more information, go to www.vizgen.com&lt;/p&gt;&lt;/div&gt;&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Vizgen is a seeking an Intern to join our technology development team and mentors in our Cambridge, MA office.&amp;nbsp; The Intern will support a series of projects in light to improve Vizgen’s software and/or bioinformatics technology. We are seeking an Intern with an academic record or experience aligned with our technology initiatives. The Intern will learn about daily operations of an exciting biotech company with disruptive technology. Help advance the field of instruments for biological research!&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Responsibilities:&amp;nbsp;&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Work alongside software developers, bioinformaticians, computation biologists and/or peers to gain insight and complete assigned tasks.&lt;/li&gt;
&lt;li&gt;Optimize new and existing data and software code(s) with emphasis on quality, maintenance, and reuse.&lt;/li&gt;
&lt;li&gt;Effectively investigate and address bugs within data systems, software, and technological errors&lt;/li&gt;
&lt;li&gt;Present materials and engage in all-company meetings with colleagues at all levels of the organization.&lt;/li&gt;
&lt;li&gt;Investigate and report solutions to novel problems.&lt;/li&gt;
&lt;li&gt;Interact directly with colleagues in resolving complex challenges.&lt;/li&gt;
&lt;li&gt;Collaborate with full-time staff to provide timely suggested resolutions to potential consumer questions and concerns.&lt;/li&gt;
&lt;li&gt;Flexibility to perform other related duties as assigned.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Requirements &amp;amp; Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Must be enrolled in a PhD or equivalent graduate degree program at an accredited institution.&lt;/li&gt;
&lt;li&gt;Must be majoring in Computer Science, Statistics, Computational Biology, Information Technology, Biochemistry, Information Studies, Biomedical Engineering, or related subject matter&lt;/li&gt;
&lt;li&gt;Some background knowledge of molecular biology concepts, computational biology, and/or bioinformatics&lt;/li&gt;
&lt;li&gt;Work experience in the life sciences industry would be a plus.&lt;/li&gt;
&lt;li&gt;Familiarity with JavaScript, Python, C# and/or bash scripting required.&lt;/li&gt;
&lt;li&gt;Experience with Windows required.&lt;/li&gt;
&lt;li&gt;Must have a technical mindset with great attention to detail.&lt;/li&gt;
&lt;li&gt;Experience with Linux highly preferred.&lt;/li&gt;
&lt;li&gt;Experience with various database technologies (SQL, NoSQL, data lake, etc.) highly preferred&lt;/li&gt;
&lt;li&gt;Familiarity with genetics &amp;amp; genomics is a plus.&lt;/li&gt;
&lt;li&gt;Some understanding of microscopy and its basic principles would be ideal.&lt;/li&gt;
&lt;li&gt;Must possess strong analytical, organizational and time management skills.&lt;/li&gt;
&lt;li&gt;Highly effective in communicating in written, verbal, and presentation form.&lt;/li&gt;
&lt;li&gt;Must be proficient and have practical knowledge in Microsoft Word, Excel, and PowerPoint.&lt;/li&gt;
&lt;li&gt;Must be able to work well within a team and independently at times with limited guidance.&lt;/li&gt;
&lt;li&gt;Must be authorized to work in the US on a permanent basis as Vizgen policy is not to provide immigration-related sponsorship for internships.&lt;/li&gt;
&lt;li&gt;Ability to work in controlled environments that may require special gowning. Gowning requirements include a wearing protective clothing over the head, face, hands, feet and body.&lt;/li&gt;
&lt;li&gt;May be asked to work in a confined area.&lt;/li&gt;
&lt;/ul&gt;&lt;div class=&quot;content-conclusion&quot;&gt;&lt;p&gt;If you aren&#x27;t sure you meet every requirement but are excited about what you read here, please consider applying! We believe diversity drives innovation.&amp;nbsp; Above all, we&#x27;re looking for the right person with skills and talent to grow the company together all while enriching your professional and scientific experience.&lt;/p&gt;
&lt;p&gt;We offer a competitive salary, meaningful stock ownership, 401K, health benefits, a great work environment and the opportunity to enter a high-growth startup company. We are recruiting candidates who have demonstrated leadership and excellence throughout their careers and are excited by the prospect of tackling challenging technical problems.&lt;/p&gt;
&lt;p&gt;&lt;em&gt;This position may be subject to pre-employment checks, including driving history check, drug screening and a background check for any convictions directly related to its duties and responsibilities. All pre-employment checks will comply with all applicable federal, state, and local laws.&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;WE ARE AN EQUAL OPPORTUNITY/AFFIRMATIVE ACTION EMPLOYER&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Vizgen affords equal employment opportunity to all qualified persons regardless of race, color, religious creed, national origin, age, military status, sexual orientation, disability, genetic information, gender identity, gender expression or gender unless based upon a bona fide occupational qualification.&lt;/p&gt;&lt;/div&gt;

Intern - Software & Bioinformatics

&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;dhkj5-0-0&quot;&gt;
&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;
&lt;p&gt;&lt;strong&gt;Company Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;FL89, Inc. is a privately held early-stage company that is leveraging advanced biological and computational tools to develop breakthroughs in our understanding of secreted protein function and regulation in human physiology. More specifically, FL89 is pairing high throughput -omics technology with AI/ML based protein structure prediction to define and discover novel therapeutic protein biology.&lt;/p&gt;
&lt;p&gt;Flagship Pioneering has conceived of and created companies such as Moderna Therapeutics (NASDAQ: MRNA), Editas Medicine (NASDAQ: EDIT), Omega Therapeutics (NASDAQ: OMGA), Seres Therapeutics (NASDAQ: MCRB), and Indigo Agriculture. Since its launch in 2000, Flagship has applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures. In 2021, Flagship Pioneering was ranked 12th globally on Fortune’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;We are seeking an energetic and motivated scientist with extensive experience in computational structural biology and developing AI/ML models for generative protein design to join our tight-knit team. The ideal candidate has superior skills in these areas, particularly as it pertains to the interplay between protein sequence, structure, and high-dimensional NGS assays, and thrives in a fast-paced and collaborative startup environment. The position will provide a unique opportunity to play a critical role in the advancement of FL89’s computational discovery and preclinical platforms, through the development of disruptive approaches for biotherapeutic drug discovery.&lt;/p&gt;
&lt;p&gt;The candidate will&amp;nbsp;apply computational models to better understand and describe protein structure-function rules that impact human health. The candidate will design and implement novel approaches to modeling protein structure, develop structural alignment tools, assign functional similarities, and work with the experimental teams to build a reiterative learning loop to identify, classify, and validate novel secreted proteins and protein functions. An ideal candidate will pride themselves on their ability to craft scientifically logical stories out of complex structural data, develop AI/ML tools to describe key structural definitions that drive biological mechanisms, and leverage discoveries into viable biomarker or therapeutic targets.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Minimum Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;PhD in computational biology (or equivalent)&lt;/li&gt;
&lt;li&gt;3-5+ years of experience implementing AI/ML models for generative protein design&lt;/li&gt;
&lt;li&gt;5-7+ years of industry experience in computational structural biology or a related field such as computational evolutionary biology, or protein engineering&lt;/li&gt;
&lt;li&gt;Demonstrated industry experience or academic achievement, as evidenced by publications in high impact journals, conference proceedings, or widely used codebase&lt;/li&gt;
&lt;li&gt;Proficiency with bioinformatics tools in the protein space (e.g. AlphaFold, Rosetta, etc.)&lt;/li&gt;
&lt;li&gt;Strong familiarity with topics of protein and macromolecular structures and interactions with other proteins&lt;/li&gt;
&lt;li&gt;Experience in developing &amp;amp; deploying machine learning platforms using modern Python frameworks for deep learning (e.g. PyTorch)&lt;/li&gt;
&lt;li&gt;Experience with cloud environments such as AWS&lt;/li&gt;
&lt;li&gt;Knowledge of best practices in software engineering for reproducibility and data management skills&lt;/li&gt;
&lt;li&gt;Ability to work in and adapt to a fast-paced environment&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Preferred Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Experience with protein co-evolution analysis&lt;/li&gt;
&lt;li&gt;Experience with NGS and bioinformatics tools&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;Flagship Pioneering is committed to&amp;nbsp;&lt;strong&gt;equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/p&gt;
&lt;/div&gt;
&lt;/div&gt;
&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/div&gt;
&lt;/div&gt;
&lt;/div&gt;

Pr. Scientist / Assoc. Dir.: Computational & Structural Biology

&lt;div class=&quot;content-intro&quot;&gt;&lt;p&gt;Vizgen, Inc. – Cambridge, MA&lt;/p&gt;
&lt;p&gt;&lt;br&gt;Vizgen is a rapidly growing company developing the next generation of spatially resolved genomic profiling tools that enable researchers to gain new insight into the biological systems that underlie human health and disease. The company&#x27;s groundbreaking MERFISH spatial transcriptomics technology images RNA molecules with high accuracy and unrivaled detection efficiency at subcellular resolution. MERFISH provides transformative insight into a wide range of tissue-scale basic research and translational medicine in oncology, immunology, neuroscience, infectious disease, developmental biology, and regenerative medicine. For more information, go to www.vizgen.com&lt;/p&gt;&lt;/div&gt;&lt;p&gt;&lt;strong&gt;Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Reporting to the Sr Director of Technology and Partnerships and working closely with Vizgen’s product development teams, the Senior Bioinformatician will be responsible for identifying and implementing areas to improve the quality of MERSCOPE data, working within cross disciplinary product development teams to evaluate the quality and consistency of MERFISH data, and designing intuitive performance metrics for a MERSCOPE measurement. We are seeking a bioinformatician with strong experience in quantitatively evaluating genomic data and image processing.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Evaluate and improve Vizgen’s staining and probe design strategies to optimize sensitivity and specificity to drive improvements to Vizgen’s MERSCOPE platform.&lt;/li&gt;
&lt;li&gt;Work closely with the wet lab team to evaluate data quality and identify ways the data can be improved computationally or experimentally.&lt;/li&gt;
&lt;li&gt;Establish pipelines to ingest publicly available datasets to evaluate the quality of internal datasets to identify relative strengths and weaknesses.&lt;/li&gt;
&lt;li&gt;Establish and implement intuitive quality metrics that quickly allow non-technical users to understand the quality of Vizgen’s data&lt;/li&gt;
&lt;li&gt;Quickly build, prototype and test code with an appropriately high level of engineering and good coding practices&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Requirements and Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Bachelor&#x27;s degree in&amp;nbsp;computational biology, mathematical biology, bioinformatics, biology&amp;nbsp;or related computational field and a minimum of 10 years of related experience&amp;nbsp;required.&lt;/li&gt;
&lt;li&gt;Or Master&#x27;s degree in&amp;nbsp;computational biology, mathematical biology, bioinformatics, biology&amp;nbsp;or related computational field and 8+ years of related experience&amp;nbsp;required.&lt;/li&gt;
&lt;li&gt;Or PhD degree in&amp;nbsp;computational biology, mathematical biology, bioinformatics, biology&amp;nbsp;or related computational field and 4+ years of related experience&amp;nbsp;highly preferred.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Equivalent combination of education and experience may be accepted in lieu of any required degree.&lt;/li&gt;
&lt;li&gt;4+ years of bioinformatics experience in the life sciences research industry&amp;nbsp;highly preferred.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Extensive background analyzing data from sequencing (single cell and bulk) and imaging (FISH and IHC) experiments.&lt;/li&gt;
&lt;li&gt;Extensive experience in Python and experience working in cloud computing environments&lt;/li&gt;
&lt;li&gt;Experience contributing to production bioinformatics pipelines.&lt;/li&gt;
&lt;li&gt;Experience working at the bench is a plus&lt;/li&gt;
&lt;li&gt;Excellent communication and presentation skills&lt;/li&gt;
&lt;li&gt;Enjoys working in entrepreneurial but collaborative team-oriented environment&lt;/li&gt;
&lt;li&gt;Highly proficient in the use of business platform tools including PowerPoint, Excel, Word, project management tools, documentation control, and other relevant software applications&lt;/li&gt;
&lt;/ul&gt;&lt;div class=&quot;content-conclusion&quot;&gt;&lt;p&gt;If you aren&#x27;t sure you meet every requirement but are excited about what you read here, please consider applying! We believe diversity drives innovation.&amp;nbsp; Above all, we&#x27;re looking for the right person with skills and talent to grow the company together all while enriching your professional and scientific experience.&lt;/p&gt;
&lt;p&gt;We offer a competitive salary, meaningful stock ownership, 401K, health benefits, a great work environment and the opportunity to enter a high-growth startup company. We are recruiting candidates who have demonstrated leadership and excellence throughout their careers and are excited by the prospect of tackling challenging technical problems.&lt;/p&gt;
&lt;p&gt;&lt;em&gt;This position may be subject to pre-employment checks, including driving history check, drug screening and a background check for any convictions directly related to its duties and responsibilities. All pre-employment checks will comply with all applicable federal, state, and local laws.&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;WE ARE AN EQUAL OPPORTUNITY/AFFIRMATIVE ACTION EMPLOYER&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Vizgen affords equal employment opportunity to all qualified persons regardless of race, color, religious creed, national origin, age, military status, sexual orientation, disability, genetic information, gender identity, gender expression or gender unless based upon a bona fide occupational qualification.&lt;/p&gt;&lt;/div&gt;

Senior Bioinformatician

&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;dhkj5-0-0&quot;&gt;
&lt;p&gt;&lt;strong&gt;Company Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;What if…&lt;/strong&gt;you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?&lt;/p&gt;
&lt;p&gt;&lt;a href=&quot;https://aprioribio.com/&quot;&gt;Apriori Bio&lt;/a&gt; is an early-stage biotechnology company with an ambitious and exciting mission: to lay the foundation for a Global Pathogen Shield protective interventions that that can neutralize a wide range of the most dangerous and rapidly evolving infectious pathogen threats.&amp;nbsp; The company is developing a revolutionary approach to this challenge and recruiting a team of top-tier scientists to build what it believes will be a powerful, first-in-category R&amp;amp;D platform.&lt;/p&gt;
&lt;p&gt;&lt;a href=&quot;https://aprioribio.com/&quot;&gt;Apriori Bio&lt;/a&gt; is a product of Flagship Pioneering’s venture creation engine, which has also given rise to companies such as Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), and Editas Medicines (NASDAQ: EDIT). Since Flagship’s founding in 2000, the firm has originated and fostered the development of more than 100 scientific ventures, resulting in over $34 billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents.&lt;/p&gt;
&lt;h3&gt;&lt;strong&gt;Job Description:&lt;/strong&gt;&lt;/h3&gt;
&lt;p&gt;Apriori Bio is seeking a &lt;strong&gt;Senior Scientist in Data Science&lt;/strong&gt; with a track record of developing and successfully applying analytical tools to high-throughput assays.&amp;nbsp; This role is positioned at a critical interface bridging high-throughput assays and computational methods designing variant-proof vaccines and antibodies against infectious disease. Experience in analysis of high-throughput functional genomics assays (e.g. deep mutational scanning) and data visualization is desired, as is technical expertise in protein engineering or structure, virology, vaccinology, and/or viral phylogenetics. The successful candidate will play a critical role in formulating and executing on a science &amp;amp; technology strategy that will allow the company to deliver against its near- and longer-term goals. This individual will join a dynamic, rapidly growing and collaborative team, and should also be comfortable in a fast-paced start-up environment.&amp;nbsp;&amp;nbsp;&lt;/p&gt;
&lt;h3&gt;&lt;strong&gt;Roles &amp;amp; Responsibilities:&lt;/strong&gt;&lt;/h3&gt;
&lt;ul&gt;
&lt;li&gt;Build robust computational tools to interpret data from viral deep mutational scanning experiments and apply learnings to product design&lt;/li&gt;
&lt;li&gt;Identify and source additional relevant external and internal datasets (e.g. viral sequence variation and phylogenetics, structural informatics) to augment the interpretation and application of viral deep mutational scanning data.&lt;/li&gt;
&lt;li&gt;Develop data visualizations to communicate learnings from analyses&lt;/li&gt;
&lt;li&gt;Collaborate with experimental and computational scientists to guide data analysis, interpret results, and build an iterative experimental cycle.&lt;/li&gt;
&lt;li&gt;Work with computational and experimental scientists to establish data management practices and SOPs to improve efficiency and reproducibility&lt;/li&gt;
&lt;li&gt;Provide technical input in support of company’s science &amp;amp; technology strategy, and monitor progress toward key strategic goals on an ongoing basis.&lt;/li&gt;
&lt;li&gt;Communicate insights and conclusions to colleagues in the scientific and leadership teams.&lt;/li&gt;
&lt;/ul&gt;
&lt;h3&gt;&lt;strong&gt;Qualifications:&lt;/strong&gt;&lt;/h3&gt;
&lt;ul&gt;
&lt;li&gt;Ph.D. or Master’s, with 5+ years of experience in computational biology, genomics, virology, immunology, or a related field.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Scientific or quantitative computing experience (python preferred) and bash scripting&lt;/li&gt;
&lt;li&gt;Experience in implementing best practices in reproducible scientific computing (git, documentation, object-oriented programming, etc.)&lt;/li&gt;
&lt;li&gt;Experience in exploratory data analysis, statistics, and statistical inference (such as machine learning, Bayesian inference, etc.)&lt;/li&gt;
&lt;li&gt;Demonstrated success in analyzing high-throughput functional assays in an industry setting&lt;/li&gt;
&lt;li&gt;Experience with protein engineering, viral antibody responses or vaccine design, phylogenetics and/or analysis of viral sequence variation.&amp;nbsp;&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Ability to work in and adapt to a fast-paced environment&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Preferred Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Previous work with viral entry proteins, biological sequence or protein structure datasets, or computational vaccine design&lt;/li&gt;
&lt;li&gt;Wet lab experience in molecular biology, genetics, or biochemistry&lt;/li&gt;
&lt;li&gt;Demonstrated experience developing visualization and/or phylogenetic software.&lt;/li&gt;
&lt;li&gt;Experience with bioinformatics and data engineering (i.e., SQL/noSQL) tools&lt;/li&gt;
&lt;li&gt;Familiarity with collaborative data science environments, such as jupyterhub, databricks, sagemaker, dataiku, or alteryx&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;Flagship Pioneering and our ecosystem companies are &lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;&lt;em&gt;Recruitment &amp;amp; Staffing Agencies:&lt;/em&gt;&lt;/strong&gt;&lt;em&gt; Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/p&gt;
&lt;/div&gt;

Senior Scientist, Data Science 

&lt;p&gt;&lt;strong&gt;What if…&lt;/strong&gt; you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies to transform human health and sustainability?&lt;/p&gt;
&lt;p&gt;Flagship Pioneering&#x27;s venture creation engine has conceived and created companies such as Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology (NASDAQ: SANA), Generate Biomedicines, and Tessera Therapeutics. Since its launch in 2000, Flagship has applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $212 billion in aggregate value. To date, Flagship has deployed over $2.5 billion in capital toward the founding and growth of its pioneering companies alongside more than $19 billion of follow-on investments from other institutions. In 2021, Flagship Pioneering was ranked 12thglobally on Fortune’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;The Company:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;FL86, Inc. is a privately held, early-stage company developing a novel genomics platform and therapeutics for diseases with a large unmet need.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Responsible for the translational validation of discovery platform targets in cell-based and in disease-relevant pharmacological models&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;The successful candidate will work both independently and as part of a team to design, plan and execute high-quality biochemical, cell-based and translational assays&lt;/li&gt;
&lt;li&gt;Lead the development and execution of cell-based assays to assess biological signaling pathways, the biological activity of small molecules, biologics or nucleotide-based compounds&lt;/li&gt;
&lt;li&gt;Define tissue and disease-specific target engagement levels, establish, and run biomarker plans and translational PK/PD assessment&lt;/li&gt;
&lt;li&gt;Critical data analysis, attention to detail, and troubleshooting abilities&lt;/li&gt;
&lt;li&gt;Mentor and train research associates as needed&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Ph.D. in Cell Biology, Molecular Biology, Biochemistry, Bioengineering or related discipline with 5+ years of experience in a biotech or pharmaceutical company (the title will be adjusted for the level of experience).&lt;/li&gt;
&lt;li&gt;Deep knowledge and understanding of cell biology. Proficient in experimental design, assay execution, troubleshooting, data analysis, and data interpretation.&lt;/li&gt;
&lt;li&gt;Extensive hands-on experience in mammalian cell culture including primary cells and in handling tissues.&lt;/li&gt;
&lt;li&gt;The ideal candidate has previous experience in cell-culture assays of cardiometabolic diseases (e.g., Diabetes, Heart Disease, Fatty Liver Disease) and relevant cell culture lines (e.g., Myocyte, Hepatocyte, pancreatic). Experience in RNA biochemistry and structural biology, cell-based genetic manipulations (e.g., siRNA, ASO) and RNA/DNA delivery is a plus.&lt;/li&gt;
&lt;li&gt;Experience in the following techniques is a plus: FACS, RT-qPCR, RNA-seq, cloning, cell culture, microscopy, IHC and quantitative image analysis, Meso Scale Discovery, HALO image analysis software.&lt;/li&gt;
&lt;li&gt;Strong written and oral presentation skills&lt;/li&gt;
&lt;li&gt;Execution focused, team oriented, and highly motivated.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Preferred Attributes:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Experience with translational cell-based and pharmacology models&amp;nbsp;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Location:&lt;/strong&gt; Cambridge, MA&amp;nbsp;&lt;/p&gt;
&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;Flagship Pioneering and our ecosystem companies are&amp;nbsp;&lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt;&amp;nbsp;regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/div&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;6ni4e-0-0&quot;&gt;&amp;nbsp;&lt;/div&gt;
&lt;/div&gt;
&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;
&lt;div class=&quot;public-DraftStyleDefault-block public-DraftStyleDefault-ltr&quot; data-offset-key=&quot;cpe78-0-0&quot;&gt;&lt;em&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/div&gt;
&lt;/div&gt;

Senior Scientist, Metabolic Cell Biology 

&lt;div class=&quot;content-intro&quot;&gt;&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;Who we are&lt;br&gt;&lt;/strong&gt;&lt;/span&gt;&lt;span class=&quot;normaltextrun&quot; style=&quot;font-size: 12pt;&quot;&gt;&lt;span style=&quot;color: black;&quot;&gt;At CarGurus (NASDAQ: CARG), our mission is to give people the power to reach their destination. We started as a small team of developers determined to bring trust and transparency to car shopping. Since then, our history of innovation and go-to-market acceleration has driven industry-leading growth. In fact, we’re the largest and fastest-growing automotive marketplace, and we’ve been profitable for over 15 years.&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;What we do&lt;/strong&gt;&lt;br&gt;The market is evolving, and we are too, moving the entire automotive journey online and guiding our customers through every step. That includes everything from the sale of an old car to the financing, purchase, and delivery of a new one. Today, tens of millions of consumers visit CarGurus.com each month, and ~30,000 dealerships use our products. But they&#x27;re not the only ones who love CarGurus—our employees do, too. We have a people-first culture that fosters&amp;nbsp;kindness, collaboration, and innovation, and empowers our Gurus with tools to fuel their career growth. Disrupting a trillion-dollar industry requires fresh and diverse perspectives. Come join us for the ride!&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;Role overview&lt;/strong&gt;&lt;/span&gt;&lt;br&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;We are looking for a &lt;strong&gt;Senior Analytics Engineer&lt;/strong&gt; with experience in data modeling to join the Data Engineering team at CarGurus as we revamp our data modeling framework in dbt. As a Senior Analytics Engineer at CarGurus, you will be responsible for transforming raw data in the data warehouse into clean, reliable, organized data models that allow our organization to make informed data-driven decisions. Our tech stack currently consists of Snowflake, dbt, and Looker, along with an in-house built ETL pipeline using Airflow.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;What you&#x27;ll do&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Design, build, and maintain scalable, modularized data models using dbt for our core data marts &lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Partner with analysts and non-technical stakeholders across the company to gather business requirements for modeling projects &lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Create explores in Looker to surface data models for self-service &lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Help create best practices and standards for data modeling, documentation, and testing &lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Coach junior team members on their modeling projects and assist with code reviews &lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Help with platform ownership tasks such as permissioning, metadata management, and maintenance for the data warehouse and Looker platform&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;What you&#x27;ll bring&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;4+ years of experience as an Analytics Engineer, Data Engineer, Product Analyst, or similar role &lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;1+ year of experience with building complex data models in dbt &lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Expert-level proficiency with SQL, including writing performant queries on large data sets &lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Experience working with cloud data warehouses (Snowflake, BigQuery, and/or Redshift) &lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Experience with Looker or a similar BI platform (Tableau, Mode) &lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Strong communication skills and ability to work effectively with both technical and non-technical stakeholders &lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Interest in coaching and mentoring junior engineers on the Analytics Engineering team &lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Bonus: Proficient with Python&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;&lt;div class=&quot;content-conclusion&quot;&gt;&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;Working at CarGurus&lt;/strong&gt; &lt;br&gt;We reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;We welcome all&lt;/strong&gt;&lt;br&gt;CarGurus strives to be a place to which people can bring the ultimate expression of themselves and their potential—starting with our hiring process. We do not discriminate based on race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation. We foster an inclusive environment that values people for their skills, experiences, and unique perspectives. That’s why we hope you’ll apply even if you don’t check every box listed in the job description. We want to know what only &lt;em&gt;you &lt;/em&gt;can bring to CarGurus.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot; data-lucid-type=&quot;application/vnd.lucid.text&quot; data-lucid-content=&quot;{&amp;quot;t&amp;quot;:&amp;quot;Working at CarGurus \nWe reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&amp;quot;,&amp;quot;m&amp;quot;:[{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;b&amp;quot;,&amp;quot;v&amp;quot;:true,&amp;quot;e&amp;quot;:19},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#000000ff&amp;quot;,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:19.999999999999996,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:19,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#1d1c1dff&amp;quot;,&amp;quot;e&amp;quot;:730},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:20,&amp;quot;e&amp;quot;:730}]}&quot;&gt;&lt;strong&gt;Additional information&lt;/strong&gt; &lt;br&gt;&lt;/span&gt;&lt;span data-lucid-type=&quot;application/vnd.lucid.text&quot; data-lucid-content=&quot;{&amp;quot;t&amp;quot;:&amp;quot;Working at CarGurus \nWe reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&amp;quot;,&amp;quot;m&amp;quot;:[{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;b&amp;quot;,&amp;quot;v&amp;quot;:true,&amp;quot;e&amp;quot;:19},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#000000ff&amp;quot;,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:19.999999999999996,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:19,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#1d1c1dff&amp;quot;,&amp;quot;e&amp;quot;:730},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:20,&amp;quot;e&amp;quot;:730}]}&quot;&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;US employees must provide proof of full vaccination against COVID-19 unless they have an approved medical or religious accommodation. &lt;/span&gt;&lt;span style=&quot;color: #ffffff;&quot;&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;#LI-H&lt;/span&gt;ybrid&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;

Senior Data Analytics Engineer

&lt;div class=&quot;content-intro&quot;&gt;&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;Who we are&lt;br&gt;&lt;/strong&gt;&lt;/span&gt;&lt;span class=&quot;normaltextrun&quot; style=&quot;font-size: 12pt;&quot;&gt;&lt;span style=&quot;color: black;&quot;&gt;At CarGurus (NASDAQ: CARG), our mission is to give people the power to reach their destination. We started as a small team of developers determined to bring trust and transparency to car shopping. Since then, our history of innovation and go-to-market acceleration has driven industry-leading growth. In fact, we’re the largest and fastest-growing automotive marketplace, and we’ve been profitable for over 15 years.&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;What we do&lt;/strong&gt;&lt;br&gt;The market is evolving, and we are too, moving the entire automotive journey online and guiding our customers through every step. That includes everything from the sale of an old car to the financing, purchase, and delivery of a new one. Today, tens of millions of consumers visit CarGurus.com each month, and ~30,000 dealerships use our products. But they&#x27;re not the only ones who love CarGurus—our employees do, too. We have a people-first culture that fosters&amp;nbsp;kindness, collaboration, and innovation, and empowers our Gurus with tools to fuel their career growth. Disrupting a trillion-dollar industry requires fresh and diverse perspectives. Come join us for the ride!&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;p&gt;&lt;strong&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Role overview&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;The Data Engineering team is looking for a highly motivated &lt;strong&gt;Principal Data Platform Engineer&lt;/strong&gt; to evolve our modern data warehousing platform to world-class levels! As CarGurus enters the next phase of dramatic growth with new data sources, new business lines, and business acquisitions, we are looking for a candidate who is interested in revamping how we do data at the company.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;What you&#x27;ll do&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Gain a deep understanding of our evolving data and analytics stack&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Define and drive tactical decisions around Data Platform domain while providing input into larger strategic decisions around data infrastructure, data quality, data observability and data governance&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Build robust and scalable data integration (ETL/ELT) pipelines using Python, SQL, dbt and Airflow&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Build and deliver high quality data architecture to support our team of Analytics Engineers, Data Analysts, Data Scientists, and various stakeholders throughout the company&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Be a technical mentor to junior engineers and expose the team to new opportunities&lt;/span&gt;&amp;nbsp;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;What you&#x27;ll bring&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;5+ years of experience as a software engineer, including 4+ years as a Data Engineer&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Professional experience developing and executing on a data warehouse and/or data platform strategy using a modern data stack – at CarGurus, we use Snowflake, dbt, airflow, and docker&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Confident and experienced looking at data platform architecture as a whole and helping to drive strategic roadmap decisions&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Ability to move quickly in a dynamic and cross-functional team environment&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Expertise in SQL, Python, and system architecture – with the ability to understand the context of a business need and build a system that addresses it&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;&lt;div class=&quot;content-conclusion&quot;&gt;&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;Working at CarGurus&lt;/strong&gt; &lt;br&gt;We reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;We welcome all&lt;/strong&gt;&lt;br&gt;CarGurus strives to be a place to which people can bring the ultimate expression of themselves and their potential—starting with our hiring process. We do not discriminate based on race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation. We foster an inclusive environment that values people for their skills, experiences, and unique perspectives. That’s why we hope you’ll apply even if you don’t check every box listed in the job description. We want to know what only &lt;em&gt;you &lt;/em&gt;can bring to CarGurus.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot; data-lucid-type=&quot;application/vnd.lucid.text&quot; data-lucid-content=&quot;{&amp;quot;t&amp;quot;:&amp;quot;Working at CarGurus \nWe reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&amp;quot;,&amp;quot;m&amp;quot;:[{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;b&amp;quot;,&amp;quot;v&amp;quot;:true,&amp;quot;e&amp;quot;:19},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#000000ff&amp;quot;,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:19.999999999999996,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:19,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#1d1c1dff&amp;quot;,&amp;quot;e&amp;quot;:730},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:20,&amp;quot;e&amp;quot;:730}]}&quot;&gt;&lt;strong&gt;Additional information&lt;/strong&gt; &lt;br&gt;&lt;/span&gt;&lt;span data-lucid-type=&quot;application/vnd.lucid.text&quot; data-lucid-content=&quot;{&amp;quot;t&amp;quot;:&amp;quot;Working at CarGurus \nWe reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&amp;quot;,&amp;quot;m&amp;quot;:[{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;b&amp;quot;,&amp;quot;v&amp;quot;:true,&amp;quot;e&amp;quot;:19},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#000000ff&amp;quot;,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:19.999999999999996,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:19,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#1d1c1dff&amp;quot;,&amp;quot;e&amp;quot;:730},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:20,&amp;quot;e&amp;quot;:730}]}&quot;&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;US employees must provide proof of full vaccination against COVID-19 unless they have an approved medical or religious accommodation. &lt;/span&gt;&lt;span style=&quot;color: #ffffff;&quot;&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;#LI-H&lt;/span&gt;ybrid&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;

Principal Data Platform Engineer

&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;dhkj5-0-0&quot;&gt;
&lt;p&gt;&lt;strong&gt;Company Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;What if…&lt;/strong&gt;you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?&lt;/p&gt;
&lt;p&gt;&lt;a href=&quot;https://aprioribio.com/&quot;&gt;Apriori Bio&lt;/a&gt; is an early-stage biotechnology company with an ambitious and exciting mission: to lay the foundation for Global Pathogen Shield protective interventions that that can neutralize a wide range of the most dangerous and rapidly evolving infectious pathogen threats.&amp;nbsp; The company is developing a revolutionary approach to this challenge and recruiting a team of top-tier scientists to build what it believes will be a powerful, first-in-category R&amp;amp;D platform.&lt;/p&gt;
&lt;p&gt;&lt;a href=&quot;https://aprioribio.com/&quot;&gt;Apriori Bio&lt;/a&gt; is a product of Flagship Pioneering’s venture creation engine, which has also given rise to companies such as Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), and Editas Medicines (NASDAQ: EDIT). Since Flagship’s founding in 2000, the firm has originated and fostered the development of more than 100 scientific ventures, resulting in over $34 billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents.&lt;strong&gt; &lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary&lt;/strong&gt;:&lt;/p&gt;
&lt;p&gt;We are seeking a highly motivated, collaborative, and detail-oriented Senior Scientist to join our growing team to develop the next generation of vaccines and antibody therapeutics for infectious disease. This is an excellent opportunity for a skilled molecular biologist to build additional skills in library-scale molecular biology, cutting-edge high throughput screening methods, and next generation sequencing. The role requires a strong background in molecular biology, attention to detail and organization, and comfort working in a fast-paced entrepreneurial environment. Experience with protein engineering, deep mutational scanning, or other functional genomics approaches is a plus. This individual will be an integral part of a highly collaborative and interdisciplinary team at the interface of virology, functional genomics, and vaccine design. This candidate should be comfortable in a fast-paced and collaborative start-up environment.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Establish robust, scalable workflows to design, clone, and characterize large scale DNA libraries.&lt;/li&gt;
&lt;li&gt;Collaborate with a larger team of scientists to leverage high throughput screening platforms (yeast/mammalian cell/viral display, etc.) to interrogate antigenicity and viral fitness at massive scale.&lt;/li&gt;
&lt;li&gt;Ensure library design, screening strategies, and analyses are tightly linked to protein structure/function and aligned with project goals.&lt;/li&gt;
&lt;li&gt;Collaborate with computational scientists to guide data analysis, interpret results, and build a rapid iterative experimental cycle.&lt;/li&gt;
&lt;li&gt;Analyze data promptly to clearly depict and communicate results to the cross-functional team and to leadership.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Basic Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Ph.D. with 5+ years of experience molecular biology, synthetic biology, genomics, bioengineering, or a related field&lt;/li&gt;
&lt;li&gt;Strong hands-on experience in molecular biology, including PCR, primer design, cloning, sequencing, sequence analysis, etc.&lt;/li&gt;
&lt;li&gt;Working knowledge of protein structure/function relationships&lt;/li&gt;
&lt;li&gt;Knowledge of modern cloning approaches (&lt;em&gt;e.g. &lt;/em&gt;Gibson, GoldenGate, etc.)&lt;/li&gt;
&lt;li&gt;Experience with next generation sequencing (Illumina, long-read, etc.)&lt;/li&gt;
&lt;li&gt;Stellar work ethic and a passion for benchwork&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Strong organizational and record-keeping skills&lt;/li&gt;
&lt;li&gt;Effective and proactive communication&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Preferred Qualifications: &lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Expertise in generating diverse DNA libraries, high-throughput cloning, and/or NGS&lt;/li&gt;
&lt;li&gt;Experience in high-throughput screening, functional genomics, and/or protein engineering&lt;/li&gt;
&lt;li&gt;Experience with antibody characterization, immunological assays, viral entry proteins, and/or cell-based functional assays&lt;/li&gt;
&lt;li&gt;Experience with automation or liquid handlers&amp;nbsp;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;Flagship Pioneering and our ecosystem companies are &lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt; regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;&lt;em&gt;Recruitment &amp;amp; Staffing Agencies:&lt;/em&gt;&lt;/strong&gt;&lt;em&gt; Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/p&gt;
&lt;/div&gt;

Senior Scientist, Molecular Biology 

&lt;div class=&quot;content-intro&quot;&gt;&lt;p&gt;Vizgen, Inc. – Cambridge, MA&lt;/p&gt;
&lt;p&gt;&lt;br&gt;Vizgen is a rapidly growing company developing the next generation of spatially resolved genomic profiling tools that enable researchers to gain new insight into the biological systems that underlie human health and disease. The company&#x27;s groundbreaking MERFISH spatial transcriptomics technology images RNA molecules with high accuracy and unrivaled detection efficiency at subcellular resolution. MERFISH provides transformative insight into a wide range of tissue-scale basic research and translational medicine in oncology, immunology, neuroscience, infectious disease, developmental biology, and regenerative medicine. For more information, go to www.vizgen.com&lt;/p&gt;&lt;/div&gt;&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Reporting to the VP of Operations, the Operations Data Engineer will lead programs to implement data warehousing/mining/management capability within Vizgen’s manufacturing operations, including production and inventory reporting, batch record warehousing and analysis, production floor statistical process control and customer complaint handling and feedback. This individual will work directly with Operations and corporate leadership to improve data analysis, visualization and interpretation and empower our team to achieve world-class operational capability and customer service.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Develop ERP-based (NetSuite) or ERP-linked systems for production reporting and inventory management that provide transparency into Manufacturing operations and agile response capability (Production Dashboards)&lt;/li&gt;
&lt;li&gt;Develop Quality Control data warehousing and mining systems that enable efficient manufacturing operations (e.g., automatic data logging), rapid response to customer issues and insight into instrument and reagent performance over time and across lots&lt;/li&gt;
&lt;li&gt;Develop production floor control systems such as Automated Batch Record systems and Statistical Process Control to enable achievement of world-class quality, delivery and cost levels&lt;/li&gt;
&lt;li&gt;Develop a robust Voice of Customer reporting system to enable effective feedback from field to factory floor&lt;/li&gt;
&lt;li&gt;Serve as a Subject Matter Expert on ERP queries and data mining (NetSuite)&lt;/li&gt;
&lt;li&gt;Develop systems for rapid implementation of approved changes into ERP&lt;/li&gt;
&lt;li&gt;Collaborate with scientists and engineers from R&amp;amp;D through manufacturing to establish effective data warehousing and analytics tools for all points in the value chain from material receipt through to customer service&lt;/li&gt;
&lt;li&gt;Assist Manufacturing Engineering in implementing an effective PM/Calibration database&lt;/li&gt;
&lt;li&gt;Assist Documentation Control with implementation of Arena Document Control Systems&lt;/li&gt;
&lt;li&gt;Develop interfaces with contract manufacturers to enable EDI for critical production and inventory information.&lt;/li&gt;
&lt;li&gt;Assist the organization with general ERP administration tasks&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Job Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;B.S. or M.S. in an Engineering, Life Sciences. Computer Sciences or Industrial Engineering field with 5+ years of industrial experience in data systems and data management&lt;/li&gt;
&lt;li&gt;Extensive experience with ERP systems, including data management, script programming and report generation a must. Familiarity with NetSuite a plus but not required.&lt;/li&gt;
&lt;li&gt;Experience with SQL databases and business analytics platforms (Power BI, QuickSight, etc.) is also a must&lt;/li&gt;
&lt;li&gt;Education or background in biotech manufacturing operations preferred&lt;/li&gt;
&lt;li&gt;Familiarity with Lean Manufacturing principles and practices strongly preferred&lt;/li&gt;
&lt;li&gt;Continuous Improvement mindset, driving he organization to optimize data management&lt;/li&gt;
&lt;li&gt;Excellent communication skills, able to explain complex data management systems in clear terms to leadership and peers&lt;/li&gt;
&lt;/ul&gt;&lt;div class=&quot;content-conclusion&quot;&gt;&lt;p&gt;If you aren&#x27;t sure you meet every requirement but are excited about what you read here, please consider applying! We believe diversity drives innovation.&amp;nbsp; Above all, we&#x27;re looking for the right person with skills and talent to grow the company together all while enriching your professional and scientific experience.&lt;/p&gt;
&lt;p&gt;We offer a competitive salary, meaningful stock ownership, 401K, health benefits, a great work environment and the opportunity to enter a high-growth startup company. We are recruiting candidates who have demonstrated leadership and excellence throughout their careers and are excited by the prospect of tackling challenging technical problems.&lt;/p&gt;
&lt;p&gt;&lt;em&gt;This position may be subject to pre-employment checks, including driving history check, drug screening and a background check for any convictions directly related to its duties and responsibilities. All pre-employment checks will comply with all applicable federal, state, and local laws.&lt;/em&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;WE ARE AN EQUAL OPPORTUNITY/AFFIRMATIVE ACTION EMPLOYER&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Vizgen affords equal employment opportunity to all qualified persons regardless of race, color, religious creed, national origin, age, military status, sexual orientation, disability, genetic information, gender identity, gender expression or gender unless based upon a bona fide occupational qualification.&lt;/p&gt;&lt;/div&gt;

Operations Data Engineer

&lt;p&gt;At Flagship Pioneering, we conceive, create, resource, and develop first-in-category life sciences companies to transform human health and sustainability. We’ve created over 100 scientific ventures, including the now familiar drug and vaccine innovator, Moderna Therapeutics.&lt;/p&gt;
&lt;p&gt;Since its inception in 2000, many of our companies have leveraged advances in computing, big data and AI. In recent years, this trend has accelerated with first-in-category life science companies such as Generate Biomedicines, Cellarity, Valo and many others that are creating breakthrough innovations using AI and ML technologies.&lt;/p&gt;
&lt;p&gt;We are looking for extraordinary computational scientists, engineers, and entrepreneurs to work alongside individuals within the Flagship Ecosystem focused on solving the most impactful challenges in AI and the life sciences.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt;Description&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;The ML Engineer will help shape the ML pipeline for our research scientists and Associates. They will take ownership of multiple code bases at different levels of production-readiness and contribute to growing the code bases. This is an exciting opportunity to be part of a fast-paced, highly dynamic entrepreneurial environment.&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Work with an interdisciplinary team of ML scientists, biologists and engineers to build the infrastructure and best practices for novel ML and DL pipelines applied to various biological problems and datasets.&lt;/li&gt;
&lt;li&gt;Work with a team to implement large machine learning models at scale on the cloud.&lt;/li&gt;
&lt;li&gt;Willingness to switch back and forth between a fast-paced prototype-heavy working environment, and a more rigorous production-oriented environment.&lt;/li&gt;
&lt;li&gt;Manage several git repositories, including organizing code merges.&lt;/li&gt;
&lt;li&gt;Ability to design, articulate, and implement best practices in software engineering across multiple projects.&lt;/li&gt;
&lt;li&gt;Monitor and evaluate new and emerging technologies and models, with an eye towards rapid prototyping and eventual integration into the full ML pipeline.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;Basic Requirements:&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;2+ years industry experience in ML Ops or equivalent.&lt;/li&gt;
&lt;li&gt;Fluency with AWS, GCP, or similar cloud-computing services.&lt;/li&gt;
&lt;li&gt;Fluency in python and standard ML tools and packages (e.g. PyTorch, PyG, &amp;nbsp;etc.).&lt;/li&gt;
&lt;li&gt;Experience with containerization and task orchestration tools (e.g. Docker, Kubernetes, Slurm)&lt;/li&gt;
&lt;li&gt;Motivated and team oriented, with an ability to thrive in a multidisciplinary environment.&lt;/li&gt;
&lt;li&gt;Ability to independently plan and implement ML engineering projects, while maintaining close communication with team members.&lt;/li&gt;
&lt;li&gt;Excellent collaboration skills. Must be able to think independently and contribute to an active intellectual environment.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;Preferred Requirements:&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Experience with a wide range of DL models (GANs, diffusion models, large language models, etc…), and the intricacies of managing experiments&lt;/li&gt;
&lt;li&gt;Familiarity with ETL pipelines for large datasets, and workflow managers (e.g. AirFlow, Prefect, etc…)&lt;/li&gt;
&lt;li&gt;Experience with data lakes&lt;/li&gt;
&lt;li&gt;Familiarity with full web-stack principles&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;Flagship Pioneering and our ecosystem companies are&amp;nbsp;&lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt;&amp;nbsp;regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Recruitment &amp;amp; Staffing Agencies&lt;/strong&gt;*: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.*&lt;/p&gt;

Machine Learning Engineer

&lt;div class=&quot;content-intro&quot;&gt;&lt;p&gt;&lt;strong&gt;About Inari...&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Inari is the SEEDesign™ company. We embrace the diversity and complexity of nature in every aspect of our business to drive innovation – to push the boundaries of what is possible. Through our unrivaled technology platform, Inari uses predictive design and advanced multiplex gene editing to develop step-change products. We are taking a nature positive approach to unlock the full potential of seed that will transform the food system. The results will lead to more productive acres delivering value creation for farmers and a more sustainable future for our planet.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Our success is dependent on great minds, collaborating to generate bright ideas and deliver exceptional outcomes.&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;We have over 270 employees, with research sites in Cambridge, MA (USA) and Ghent (Belgium), as well as a product development site in West Lafayette, IN (USA). We’ve deliberately built a team that brings diversity of thought to all aspects of our business, to generate new ideas, approaches, and ways of operating. And we&#x27;ve intentionally combined experience with potential, bringing agriculture industry experts with the desire to innovate together with bright minds from academia, human therapeutics, software, and consulting. If you want to be part of a diverse and inclusive team developing unique solutions to feed the world while protecting our planet’s natural resources, we’d love to hear from you!&lt;/p&gt;&lt;/div&gt;&lt;p&gt;&lt;strong&gt;About the Role&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;You will assist in the evaluation of novel RNA technology designed to facilitate genome editing in plants. The work includes&amp;nbsp;&lt;em&gt;in vitro&lt;/em&gt;&amp;nbsp;synthesis and characterization of RNA, evaluation of RNA performance in&amp;nbsp;both stable and transient systems, vector construction and characterization of genome edited plants.&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;As an intern, you will…&amp;nbsp;&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Assist in the design of&amp;nbsp;&lt;em&gt;in vitro&lt;/em&gt;transcription&amp;nbsp;plasmid templates&lt;/li&gt;
&lt;li&gt;Prepare and characterize&amp;nbsp;&lt;em&gt;in vitro&lt;/em&gt;transcribed RNA&lt;/li&gt;
&lt;li&gt;Support the evaluation of RNA application methods to different plant tissues&lt;/li&gt;
&lt;li&gt;Characterize treated plants for the presence of genome edits&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;As an intern, you bring....&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Basic experience in molecular biology techniques including plasmid preparation, restriction analysis, DNA ligation, DNA sequence analysis and PCR&lt;/li&gt;
&lt;li&gt;Very good aseptic laboratory technique&lt;/li&gt;
&lt;li&gt;Good record keeping skills.&lt;/li&gt;
&lt;li&gt;Knowledge of plant molecular biology techniques like leaf infiltration and plant transformation&lt;/li&gt;
&lt;li&gt;Experience with plant transient assay systems like hairy roots is a plus&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;

Intern, Plant Biology

&lt;div class=&quot;&quot; data-block=&quot;true&quot; data-editor=&quot;c12n7&quot; data-offset-key=&quot;dhkj5-0-0&quot;&gt;
&lt;p&gt;&lt;strong&gt;What if…&lt;/strong&gt;&amp;nbsp;you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?&lt;/p&gt;
&lt;p&gt;Metaphore Biotechnologies is an early-stage biotechnology company with an ambitious and exciting mission: to reimagine drug discovery and vaccine design. The company is developing a first-in-class platform for the intelligent design of molecular mimicry. Our platform integrates massively parallel assays with machine-learning-guided protein engineering to navigate the combinatorial space of molecular interactions and design protein-protein interfaces with exquisite precision.&lt;/p&gt;
&lt;p&gt;Metaphore Biotechnologies is a product of Flagship Pioneering&#x27;s venture creation engine, which has also given rise to companies such as Moderna Therapeutics (NASDAQ: MRNA), Editas Medicine (NASDAQ: EDIT), Omega Therapeutics (NASDAQ: OMGA), Seres Therapeutics (NASDAQ: MCRB), and Indigo Agriculture. Since its launch in 2000, Flagship has applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures. In 2021, Flagship Pioneering was ranked 12th globally on Fortune’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Position Summary:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Metaphore Biotechnologies is seeking an entrepreneurial and strategic Vice President, Head of Data Science. In this role, you will serve as a critical part of Metaphore&#x27;s R&amp;amp;D Leadership Team, crafting a scientific, technical, and strategic vision linking the department of Computational Science with Discovery / Protein Engineering and Translational Sciences. You will lead the computational team toward fulfilling the most impactful vision for Metaphore, accelerating and expanding the computational platform through scientific innovation, strategic decision-making, and operational excellence. The ideal candidate will bring substantial experience in the application of machine learning to the design of protein therapeutics such as monoclonal antibodies. Strong leadership and team building skills are essential, as are an innovative outlook and a propensity for leveraging and inventing novel technologies for the generation of new, transformative medicines.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Key Responsibilities:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Design a vision for a first-in-class computational and machine learning platform poised to unlock the therapeutic potential of molecular mimicry&lt;/li&gt;
&lt;li&gt;Collaborate with the broader leadership team to develop the company’s scientific strategy&lt;/li&gt;
&lt;li&gt;Oversee the development of computational infrastructure including integrations with lab automation, NGS data pipelines, databases, ETL services, and user interfaces&lt;/li&gt;
&lt;li&gt;Develop strategies to leverage data from high-throughput antibody discovery and library-based protein engineering to inform computational protein design&lt;/li&gt;
&lt;li&gt;Identify opportunities to expand the platform through commercial or in-house computational tools&lt;/li&gt;
&lt;li&gt;Collaborate closely with Discovery / Protein Engineering to establish capabilities to produce large datasets that optimally inform both machine learning and biophysical modeling&lt;/li&gt;
&lt;li&gt;Recruit and develop a top-performing computational team, supporting a creative, open culture motivated by the potential for scientific novelty and patient impact&lt;/li&gt;
&lt;li&gt;Support the continued protection, creation, and expansion of the company’s intellectual property&lt;/li&gt;
&lt;li&gt;Develop relationships with Flagship Pioneering’s broader data science community&lt;/li&gt;
&lt;li&gt;Establish and oversee external projects and scientific collaborations&lt;/li&gt;
&lt;li&gt;Identify, onboard, and leverage key external datasets&lt;/li&gt;
&lt;li&gt;Present to the company’s Board of Directors, Scientific Advisors, and external stakeholders&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Qualifications:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;12+ years of R&amp;amp;D experience across biotech/tech and academia including leadership of mid-size data science teams&lt;/li&gt;
&lt;li&gt;PhD or equivalent in computational biology, computer science, or a related field&lt;/li&gt;
&lt;li&gt;Experience applying machine learning to protein engineering&lt;/li&gt;
&lt;li&gt;Experience collaborating with wet lab scientists and managers&lt;/li&gt;
&lt;li&gt;Well-developed executive skills demonstrating sound business judgment, the willingness to seek and incorporate other perspectives, balance alternatives, the courage to make decisions based on incomplete information, establish priorities and apply resources effectively&lt;/li&gt;
&lt;li&gt;Ability to clearly and compellingly communicate Metaphore Biotechnologies&#x27; vision to external parties&lt;/li&gt;
&lt;li&gt;Demonstrated credibility in R&amp;amp;D and academic communities&lt;/li&gt;
&lt;li&gt;Demonstrated ability to work with highly technical teams in a fast-paced environment&lt;/li&gt;
&lt;li&gt;Ability to identify and creatively solve scientific and leadership challenges&lt;/li&gt;
&lt;li&gt;Ability to develop and recruit top scientific and engineering talent&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;Flagship Pioneering and our ecosystem companies are&amp;nbsp;&lt;strong&gt;committed to equal employment opportunity&lt;/strong&gt;&amp;nbsp;regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;&lt;em&gt;Recruitment &amp;amp; Staffing Agencies&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.&lt;/em&gt;&lt;/p&gt;
&lt;/div&gt;

Head of Data Science 

&lt;div class=&quot;content-intro&quot;&gt;&lt;p&gt;&lt;strong&gt;About Inari...&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Inari is the SEEDesign™ company. We embrace the diversity and complexity of nature in every aspect of our business to drive innovation – to push the boundaries of what is possible. Through our unrivaled technology platform, Inari uses predictive design and advanced multiplex gene editing to develop step-change products. We are taking a nature positive approach to unlock the full potential of seed that will transform the food system. The results will lead to more productive acres delivering value creation for farmers and a more sustainable future for our planet.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Our success is dependent on great minds, collaborating to generate bright ideas and deliver exceptional outcomes.&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;We have over 230 employees, with research sites in Cambridge, MA (USA) and Ghent (Belgium), as well as a product development site in West Lafayette, IN (USA). We’ve deliberately built a team that brings diversity of thought to all aspects of our business, to generate new ideas, approaches, and ways of operating. And we&#x27;ve intentionally combined experience with potential, bringing agriculture industry experts with the desire to innovate together with bright minds from academia, human therapeutics, software, and consulting. If you want to be part of a diverse and inclusive team developing unique solutions to feed the world while protecting our planet’s natural resources, we’d love to hear from you!&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;We are looking for a highly-motivated and dedicated Bioinformatics Data Analyst to join our fast-growing team at Inari Cambridge site. The Bioinformatics Data Analyst will support bioinformatics pipeline and tool development on the science platform and provide data analysis support for the connection with product development. She/he, In this role, you will provide bioinformatics programming and data analysis support for multiple projects, and work with other scientists and data analysts on the science platform, and the engineering team for internal bioinformatics tool development, and support bioinformatics pipeline development to meet the needs for&amp;nbsp; science projects and cross functional collaboration. She/he will be able to clearly communicate bioinformatics code and pipeline to different audiences.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;The right candidate must be well organized and efficient to deliver the high quality code and results. The ability to take initiative and be willing to explore new things are essential for this role. She/he must enjoy a &quot;start-up&quot; atmosphere and be willing to take on additional tasks and responsibilities as needed to achieve goals and deliverables. We are committed and passionate about developing and commercializing 21st-century solutions to address global food challenges, and we are looking for people who share that passion. The role will be based in Cambridge, MA.&amp;nbsp;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;KEY RESPONSIBILITIES:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;The Bioinformatics Data Analyst will support designing, implementing and maintaining bioinformatics pipelines and tools.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Work with Project Lead and other Scientists to develop the pipeline and execute the data analysis related to science projects&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Work with Platform Lead to provide bioinformatics programming and data analysis support for platform internal tool development and for cross functional collaborations&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Build and maintain custom reproducible bioinformatics pipelines and reports to support new scientific initiatives&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Develop bioinformatics code to continue improving guide nomination toolbox to meet new needs for science projects and product development&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Implement bioinformatics algorithms and models to predict editing and editing outcome&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Meta-analysis of gene editing data across science and product development for specific purpose&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Diagnostic the editing pattern, sequence signature and chromatin environment to understand DNA repair outcomes&amp;nbsp;&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Help analyze, track, and report on overall pipeline capacity, making recommendations for where and how we can improve&amp;nbsp;&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Proactively fill in the gaps and adapt to change in a fast paced, dynamic research environment&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Maintain detailed and organized analysis records including datasets and codes as required&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Actively troubleshoot and develop effective solutions when problems occur&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Participate in scientific discussions and present research outcomes to peers and management&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;REQUIRED SKILLS/EXPERIENCE:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;BS or MS in Computer Science, Bioinformatics, Genetics, Genomics, Mathematics, Statistics, Plant Breeding, or other relevant scientific field&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Experience with data science tools, pipeline development and ability to design and build bioinformatics pipelines and tools&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Proficient coding in Python and or R&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Familiar with cloud computing environments&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Understanding of genome science, molecular biology and bioinformatics concepts, processes, and tools&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Ability to communicate computational concepts and explain your work to a wide variety of audiences&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Strong track record of developing creative solutions to complex problems&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;An efficient and well organized approach to deliver high quality results on time&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;A strong sense of purpose and drive to develop unique, high impact solutions.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Adaptability and enthusiasm for new challenges, innate curiosity, and a passion for learning.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Creative and strategic thinking, willingness to be bold and take risks, and the ability to recognize and learn from failure.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;A collaborative mindset that is open to giving and receiving ideas, perspectives, and feedback.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Ability to work both independently and deliver on responsibilities within a highly collaborative environment.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Ability to effectively communicate with a diverse range of individuals and audiences.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;ADDITIONAL DESIRED SKILLS/EXPERIENCE:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Experience in the industry&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Experience with machine learning libraries like TensorFlow and/or PyTorch&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Previous experience working with plant genomic data&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Knowledge and experience with genome editing technologies&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Experience with single cell data analysis&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;

Bioinformatics Data Analyst

&lt;div class=&quot;content-intro&quot;&gt;&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;Who we are&lt;br&gt;&lt;/strong&gt;&lt;/span&gt;&lt;span class=&quot;normaltextrun&quot; style=&quot;font-size: 12pt;&quot;&gt;&lt;span style=&quot;color: black;&quot;&gt;At CarGurus (NASDAQ: CARG), our mission is to give people the power to reach their destination. We started as a small team of developers determined to bring trust and transparency to car shopping. Since then, our history of innovation and go-to-market acceleration has driven industry-leading growth. In fact, we’re the largest and fastest-growing automotive marketplace, and we’ve been profitable for over 15 years.&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;What we do&lt;/strong&gt;&lt;br&gt;The market is evolving, and we are too, moving the entire automotive journey online and guiding our customers through every step. That includes everything from the sale of an old car to the financing, purchase, and delivery of a new one. Today, tens of millions of consumers visit CarGurus.com each month, and ~30,000 dealerships use our products. But they&#x27;re not the only ones who love CarGurus—our employees do, too. We have a people-first culture that fosters&amp;nbsp;kindness, collaboration, and innovation, and empowers our Gurus with tools to fuel their career growth. Disrupting a trillion-dollar industry requires fresh and diverse perspectives. Come join us for the ride!&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;Role overview&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;CarGurus is looking for a &lt;strong&gt;Director of Engineering &lt;/strong&gt;to lead multiple areas including our Cloud Center of Excellence, Site Reliability, Database engineering and Observability teams. Reporting to the VP of Platform Engineering and working closely with Engineering peers, you will be responsible for transitioning our core infrastructure team into a modern cloud center of excellence.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Additionally, you will be responsible for the overall reliability and availability of our core product and surrounding applications running in our cloud environments (AWS, Kubernetes). You’ll own and develop our SRE tactics, observability tools, and services, directly engage with the rest of the Platform, Data, and Product Engineering teams to improve uptime, reliability, and resiliency of our application stack. You’ll also own the building of self-service tooling and automation to supervise the health of our applications and infrastructure.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;What you&#x27;ll do&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Lead multiple teams including Cloud center of excellence, Site Reliability Engineering (SRE), Observability (o11y), and Database as a Service (DBaaS).&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Be a thought leader around AWS best practices, governance models and helping CarGurus get the most out of its AWS partnership.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Advance Site Reliability Engineering as a practice across Engineering especially during the transition from a monolith to microservices.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Be passionate about growing careers and mentoring engineers across both the individual contributor and manager tracks.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Use Agile scrum to deliver on the team’s commitments and strengthen the team&#x27;s velocity over time.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Guide the team on standard methodologies as they deliver on their goals around distributed tracing&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Work with the team to set quarterly departmental goals and metrics for the team.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Coach, mentor, train and develop a growing engineering team. Engineers feel motivated when they feel like they are valued, delivering and learning. Help make that happen.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;What you&#x27;ll bring&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Previous experience leading/running multiple teams of Cloud, SRE and/or observability engineers.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Strong practitioner of Agile scrum methodology and ability to mentor the team on best practices as and when needed.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Making sure there is organization-wide alignment on Cloud and SRE practices across C-level executives as well as various engineering leaders.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Experience driving metrics for the organization&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Experience with affecting change and establishing standard methodologies where needed.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Broad exposure in Cloud, SRE, o11y and DB tools such as AWS, Prometheus, grafana, alertmanager, honeycomb, Graylog, MySQL, clusterControl, opsGenie, Looker, Terraform, k8s&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;You&#x27;re comfortable talking about SLOs, SLIs, SLAs, incident management, and building a culture of reliability and transparency. You have empathy for our customers and our engineers who use our systems and are eager to make improvements for them.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Experience with Business and how to balance the business needs, RTO, RPO, and cost.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Broadly familiar with information security, configuration management, and infrastructure orchestration.&lt;/span&gt;&lt;/li&gt;
&lt;li&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;Ability to translate broad company strategies into clear, specific objectives and impactful plans.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;&lt;div class=&quot;content-conclusion&quot;&gt;&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;Working at CarGurus&lt;/strong&gt; &lt;br&gt;We reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;&lt;strong&gt;We welcome all&lt;/strong&gt;&lt;br&gt;CarGurus strives to be a place to which people can bring the ultimate expression of themselves and their potential—starting with our hiring process. We do not discriminate based on race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation. We foster an inclusive environment that values people for their skills, experiences, and unique perspectives. That’s why we hope you’ll apply even if you don’t check every box listed in the job description. We want to know what only &lt;em&gt;you &lt;/em&gt;can bring to CarGurus.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-size: 12pt;&quot; data-lucid-type=&quot;application/vnd.lucid.text&quot; data-lucid-content=&quot;{&amp;quot;t&amp;quot;:&amp;quot;Working at CarGurus \nWe reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&amp;quot;,&amp;quot;m&amp;quot;:[{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;b&amp;quot;,&amp;quot;v&amp;quot;:true,&amp;quot;e&amp;quot;:19},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#000000ff&amp;quot;,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:19.999999999999996,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:19,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#1d1c1dff&amp;quot;,&amp;quot;e&amp;quot;:730},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:20,&amp;quot;e&amp;quot;:730}]}&quot;&gt;&lt;strong&gt;Additional information&lt;/strong&gt; &lt;br&gt;&lt;/span&gt;&lt;span data-lucid-type=&quot;application/vnd.lucid.text&quot; data-lucid-content=&quot;{&amp;quot;t&amp;quot;:&amp;quot;Working at CarGurus \nWe reward our Gurus’ curiosity and passion with best-in-class benefits and compensation, including equity for all employees, both when they start and as they continue to grow with us. Our career development and corporate giving programs, as well as our employee resource groups (ERGs) and communities, help people build connections while making an impact in personally meaningful ways. A flexible hybrid model and robust time off policies encourage work-life balance and individual well-being. Thoughtful perks like daily free lunch, a new car discount, meditation and fitness apps, commuting cost coverage, and more help our people create space for what matters most in their personal and professional lives.&amp;quot;,&amp;quot;m&amp;quot;:[{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;b&amp;quot;,&amp;quot;v&amp;quot;:true,&amp;quot;e&amp;quot;:19},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#000000ff&amp;quot;,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:0,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:19.999999999999996,&amp;quot;e&amp;quot;:21},{&amp;quot;s&amp;quot;:19,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;a&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;left&amp;quot;},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;p&amp;quot;,&amp;quot;v&amp;quot;:1.1036906734302876},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;c&amp;quot;,&amp;quot;v&amp;quot;:&amp;quot;#1d1c1dff&amp;quot;,&amp;quot;e&amp;quot;:730},{&amp;quot;s&amp;quot;:21,&amp;quot;n&amp;quot;:&amp;quot;s&amp;quot;,&amp;quot;v&amp;quot;:20,&amp;quot;e&amp;quot;:730}]}&quot;&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;US employees must provide proof of full vaccination against COVID-19 unless they have an approved medical or religious accommodation. &lt;/span&gt;&lt;span style=&quot;color: #ffffff;&quot;&gt;&lt;span style=&quot;font-size: 12pt;&quot;&gt;#LI-H&lt;/span&gt;ybrid&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;

Data Engineer Jobs in Cambridge